WordNet

the 13th letter of the Roman alphabet (同)m
the imperial dynasty of China from 1368 to 1644 (同)Ming dynasty
a form of address for a woman (同)Ms.

PrepTutorEJDIC

Mach number / mark[s] / Monsieur
(中国の)明,明朝(1368‐1644)
mendeleviumの化学記号

English Journal

Phospholipase A and glycerophosphodiesterase activities in the cell membrane of Mycoplasma hyorhinis.

Kornspan JD, Rottem S.SourceDepartment of Microbiology and Molecular Genetics, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
FEMS microbiology letters.FEMS Microbiol Lett.2012 Apr 16. doi: 10.1111/j.1574-6968.2012.02571.x. [Epub ahead of print]
Mycoplasma hyorhinis, the major contaminant of tissue cultures, has been implicated in a variety of diseases in swine. Most human and animal mycoplasmas remain attached to the surface of epithelial cells. Nonetheless, we have recently shown that M. hyorhinis is able to invade and survive within non-
PMID 22507126

Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues.

Vande Voorde J, Gago F, Vrancken K, Liekens S, Balzarini J.AbstractWe demonstrate that the cytostatic and antiviral activity of pyrimidine nucleoside analogues is markedly decreased by a Mycoplasma hyorhinis infection and show that the phosphorolytic activity of the mycoplasmas is responsible for this. Since mycoplasmas are (i) an important cause of secondary infections in immunocompromised (e.g. HIV-infected) patients, and (ii) known to preferentially colonize tumor tissue in cancer patients, catabolic mycoplasma enzymes may compromise efficient chemotherapy of virus infections and cancer. In the genome of M. hyorhinis, a thymidine phosphorylase (TP) gene has been annotated. This gene was cloned, expressed in Escherichia coli and kinetically characterized. Whereas the mycoplasma TP efficiently catalyzes the phosphorolysis of thymidine (Km = 473 µM) and deoxyuridine (Km = 578 µM), it prefers uridine (Km = 92 µM) as a substrate. Our kinetic data and sequence analysis revealed that the annotated M. hyorhinis TP belongs to the nucleoside phosphorylase (NP)-II class pyrimidine nucleoside phosphorylases (PyNP), and is distinct from the NP-II class TP and NP-I class uridine phosphorylases (UP). M. hyorhinis PyNP also markedly differs from TP and UP in its substrate specificity towards therapeutic nucleoside analogues and susceptibility to clinically relevant drugs. Several kinetic properties of mycoplasma PyNP were explained by in silico analyses.
The Biochemical journal.Biochem J.2012 Apr 4. [Epub ahead of print]
We demonstrate that the cytostatic and antiviral activity of pyrimidine nucleoside analogues is markedly decreased by a Mycoplasma hyorhinis infection and show that the phosphorolytic activity of the mycoplasmas is responsible for this. Since mycoplasmas are (i) an important cause of secondary infec
PMID 22475552

Japanese Journal

Mycoplasma hyorhinis実験感染豚における病態と抗体検出ELISA (第37回日本マイコプラズマ学会学術集会) -- (シンポジウムモリキューテスの宿主適応進化とユニークな病態/病原機構ヒト・動物マイコプラズマ感染症の病態)

片山宜郎,奥田陽,近田須美子 [他]
日本マイコプラズマ学会雑誌 (37), 65-68, 2010-06-10
NAID 40018819697

Nitric Oxide Causes Anoikis through Attenuation of E-Cadherin and Activation of Caspase-3 in Human Gastric Carcinoma AZ-521 Cells Infected with Mycoplasma hyorhinis

OBARA Hisato,HARASAWA Ryô
Journal of Veterinary Medical Science advpub(0), 1002130166, 2010
… Mycoplasma hyorhinis (M. … hyorhinis) infection leads the cultured cells to various biological alterations on cell metabolisms including apoptosis. … hyorhinis has mainly been considered due to mycoplasmal endonucleases. … hyorhinis was enhanced by addition of L-ascorbic acid to the cell cultures. … hyorhinis infection activated cellular iNOS, we examined the hypothesis that nitric oxide (NO) exerts apoptotic effect to M. …
NAID 130000264282