Mycoplasma hyorhinis

マイコプラズマ・ハイオリニス、マイコプラズマ・ヒオリニス

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M. hyorhinis

WordNet

1. any of a group of small parasitic bacteria that lack cell walls and can survive without oxygen; can cause pneumonia and urinary tract infection

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/12/20 07:52:20」(JST)

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Mycoplasma hyorhinis
Scientific classification
Kingdom:	Bacteria
Division:	Firmicutes
Class:	Mollicutes
Order:	Mycoplasmatales
Family:	Mycoplasmataceae
Genus:	Mycoplasma
Species:	M. hyorhinis

Mycoplasma hyorhinis is a member of the Mycoplasmatales family. This bacterium is often found as a commensal in the respiratory tract of pigs. It is thought to facilitate and exacerbate the development of diseases such as porcine enzootic pneumonia and porcine reproductive and respiratory syndrome (PRRS). Rarely, it may cause mycoplasma arthritis, mycoplasmal polyserositis or mycoplasma septicaemia in piglets without the involvement of other bacteria. This presents as polyarthritis or polyserositis.

Clinical signs and diagnosis

A variety of clinical signs are seen in piglets less than 10-weeks old.

Lameness, polyserositis and joint swelling are the most common symptoms. A foul-smelling discharge from the ears can occur secondary to otitis. Less specific signs include poor coat quality, pyrexia, cardiovascular, gastrointestinal, neurological and respiratory signs.

Bacterial culture, immunofluorescent antibody testing (IFAT), complement fixation test and haemagglutination can all be used to confirm the diagnosis.

Treatment

Antibiotics are the treatment of choice.

See also

• Mycoplasma

References

• "Mycoplasma hyorhinis". Wikivet. http://en.wikivet.net/Mycoplasma_hyorhinis. Retrieved 13 September 2011.

UpToDate Contents

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• 1. 小児におけるマイコプラズマ肺炎感染 mycoplasma pneumoniae infection in children
• 2. 成人における肺炎マイコプラズマ感染症 mycoplasma pneumoniae infection in adults
• 3. 小児および思春期における急性感染性咽頭炎の診断へのアプローチ approach to diagnosis of acute infectious pharyngitis in children and adolescents
• 4. 難治性肺炎 nonresolving pneumonia
• 5. 成人における急性気管支炎 acute bronchitis in adults

English Journal

• Phospholipase A and glycerophosphodiesterase activities in the cell membrane of Mycoplasma hyorhinis.

• Kornspan JD, Rottem S.SourceDepartment of Microbiology and Molecular Genetics, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
• FEMS microbiology letters.FEMS Microbiol Lett.2012 Apr 16. doi: 10.1111/j.1574-6968.2012.02571.x. [Epub ahead of print]
• Mycoplasma hyorhinis, the major contaminant of tissue cultures, has been implicated in a variety of diseases in swine. Most human and animal mycoplasmas remain attached to the surface of epithelial cells. Nonetheless, we have recently shown that M. hyorhinis is able to invade and survive within non-
• PMID 22507126

• Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues.

• Vande Voorde J, Gago F, Vrancken K, Liekens S, Balzarini J.AbstractWe demonstrate that the cytostatic and antiviral activity of pyrimidine nucleoside analogues is markedly decreased by a Mycoplasma hyorhinis infection and show that the phosphorolytic activity of the mycoplasmas is responsible for this. Since mycoplasmas are (i) an important cause of secondary infections in immunocompromised (e.g. HIV-infected) patients, and (ii) known to preferentially colonize tumor tissue in cancer patients, catabolic mycoplasma enzymes may compromise efficient chemotherapy of virus infections and cancer. In the genome of M. hyorhinis, a thymidine phosphorylase (TP) gene has been annotated. This gene was cloned, expressed in Escherichia coli and kinetically characterized. Whereas the mycoplasma TP efficiently catalyzes the phosphorolysis of thymidine (Km = 473 µM) and deoxyuridine (Km = 578 µM), it prefers uridine (Km = 92 µM) as a substrate. Our kinetic data and sequence analysis revealed that the annotated M. hyorhinis TP belongs to the nucleoside phosphorylase (NP)-II class pyrimidine nucleoside phosphorylases (PyNP), and is distinct from the NP-II class TP and NP-I class uridine phosphorylases (UP). M. hyorhinis PyNP also markedly differs from TP and UP in its substrate specificity towards therapeutic nucleoside analogues and susceptibility to clinically relevant drugs. Several kinetic properties of mycoplasma PyNP were explained by in silico analyses.
• The Biochemical journal.Biochem J.2012 Apr 4. [Epub ahead of print]
• We demonstrate that the cytostatic and antiviral activity of pyrimidine nucleoside analogues is markedly decreased by a Mycoplasma hyorhinis infection and show that the phosphorolytic activity of the mycoplasmas is responsible for this. Since mycoplasmas are (i) an important cause of secondary infec
• PMID 22475552

Japanese Journal

• Mycoplasma hyorhinis実験感染豚における病態と抗体検出ELISA (第37回日本マイコプラズマ学会学術集会) -- (シンポジウム モリキューテスの宿主適応進化とユニークな病態/病原機構 ヒト・動物マイコプラズマ感染症の病態)

• 片山 宜郎,奥田 陽,近田 須美子 [他]
• 日本マイコプラズマ学会雑誌 (37), 65-68, 2010-06-10
• NAID 40018819697

• Nitric Oxide Causes Anoikis through Attenuation of E-Cadherin and Activation of Caspase-3 in Human Gastric Carcinoma AZ-521 Cells Infected with Mycoplasma hyorhinis

• OBARA Hisato,HARASAWA Ryô
• Journal of Veterinary Medical Science advpub(0), 1002130166, 2010
• … Mycoplasma hyorhinis (M. … hyorhinis) infection leads the cultured cells to various biological alterations on cell metabolisms including apoptosis. … hyorhinis has mainly been considered due to mycoplasmal endonucleases. … hyorhinis was enhanced by addition of L-ascorbic acid to the cell cultures. …
• NAID 130000264282

Related Links

• Mycoplasma hyorhinis - Wikipedia, the free encyclopedia

[edit] Introduction. Mycoplasma hyorhinis is a member of the Mycoplasmatales family. This bacterium is often found as a commensal in the respiratory tract of pigs. It is thought to facilitate and exacerbate the development of diseases such as ...

• Mycoplasma hyorhinis - Should We Care? | Health content from ...

5 Jul 2011 ... Bacterial diseases have a significant economic impact in today's swine industry by causing an increase in mortality rates and a reduction in feed efficiency and growth.

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Mycoplasma hyorhinis、M. hyorhinis

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マイコプラズマ・ヒオリニス

「マイコプラズマ・ヒオリニス」

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Mycoplasma hyorhinis

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マイコプラズマ・ハイオリニス

「M. hyorhinis」

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• マイコプラズマ・ハイオリニス

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Mycoplasma hyorhinis