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Leiden
City and municipality
Flag Coat of arms
Location in South Holland
Coordinates: 52°10′N 4°29′E
Country	Netherlands
Province	South Holland
Government
• Body	Municipal council
• Mayor	Henri Lenferink (PvdA)
Area
• Municipality	23.27 km2 (8.98 sq mi)
• Land	21.91 km2 (8.46 sq mi)
• Water	1.36 km2 (0.53 sq mi)
Elevation	0 m (0 ft)
Population  (Municipality, January 2019; Urban and Metro, May 2014)
• Municipality	124,899
• Density	5,701/km2 (14,770/sq mi)
• Urban	258,923
• Metro	344,299
Demonym(s)	Leidenaar
Time zone	UTC+1 (CET)
• Summer (DST)	UTC+2 (CEST)
Postcode	2300–2334
Area code	071
Website	Official website

Topographic map of Leiden.

Leiden (/ˈlaɪdən/, Dutch: [ˈlɛi̯də(n)] (listen); in English and archaic Dutch also Leyden) is a city and municipality in the province of South Holland, Netherlands. The municipality of Leiden had a population of 123,856 in August 2017, but the city forms one densely connected agglomeration with its suburbs Oegstgeest, Leiderdorp, Voorschoten and Zoeterwoude with 206,647 inhabitants. The Netherlands Central Bureau of Statistics (CBS) further includes Katwijk in the agglomeration which makes the total population of the Leiden urban agglomeration 270,879, and in the larger Leiden urban area also Teylingen, Noordwijk, and Noordwijkerhout are included with in total 348,868 inhabitants. Leiden is located on the Oude Rijn, at a distance of some 20 kilometres (12 miles) from The Hague to its south and some 40 km (25 mi) from Amsterdam to its north. The recreational area of the Kaag Lakes (Kagerplassen) lies just to the northeast of Leiden.

A university city since 1575, Leiden has been one of Europe's most prominent scientific centres for more than four centuries. Leiden is a typical university city, university buildings are scattered throughout the city and the many students from all over the world give the city a bustling, vivid and international atmosphere. Many important scientific discoveries have been made here, giving rise to Leiden's motto: ‘City of Discoveries’. The city houses Leiden University, the oldest university of the Netherlands, and Leiden University Medical Center. Leiden University is one of Europe's top universities, with thirteen Nobel Prize winners. It is a member of the League of European Research Universities and positioned highly in all international academic rankings. It is twinned with Oxford, the location of the United Kingdom's oldest university. Leiden University and Leiden University of Applied Sciences (Leidse Hogeschool) together have around 35,000 students. Modern scientific medical research and teaching started in the early 18th century in Leiden with Boerhaave.

Leiden is a city with a rich cultural heritage, not only in science, but also in the arts. One of the world's most famous painters, Rembrandt, was born and educated in Leiden. Other famous Leiden painters include Lucas van Leyden, Jan van Goyen and Jan Steen.

History

See also: Timeline of Leiden

Historical population

Year	Pop.	±% p.a.
1398	5,000	—
1497	11,000	+0.80%
1514	14,250	+1.53%
1574	12,456	−0.22%
1581	12,144	−0.36%
1622	44,745	+3.23%
1632	44,000	−0.17%
1665	67,000	+1.28%
1732	70,000	+0.07%
1750	38,105	−3.32%
1795	30,955	−0.46%
Source: Lourens & Lucassen 1997, pp. 112–114

Leiden was formed on an artificial hill (today called the Burcht van Leiden) at the confluence of the rivers Oude and Nieuwe Rijn (Old and New Rhine). In the oldest reference to this, from circa 860, the settlement was called Leithon. The name is said to be from Germanic *leitha- "canal" in dative pluralis, thus meaning "at the canals". "Canal" is actually not the completely proper word. A leitha (later "lede") was a human-modified natural river, partly natural, partly artificial.

Leiden has in the past erroneously been associated with the Roman outpost Lugdunum Batavorum. This particular castellum was thought to be located at the Burcht of Leiden, and the city's name was thought to be derived from the Latin name Lugdunum. However the castellum was in fact closer to the town of Katwijk, whereas the Roman settlement near modern-day Leiden was called Matilo.

Windmill museum De Valk

The landlord of Leiden, situated in a stronghold on the hill (motte), was initially subject to the Bishop of Utrecht but around 1100 the burgraves became subject to the county of Holland. This county got its name in 1101 from a domain near the stronghold: Holtland or Holland.

Leiden was sacked in 1047 by Emperor Henry III. Early 13th century, Ada, Countess of Holland took refuge here when she was fighting in a civil war against her uncle, William I, Count of Holland. He besieged the stronghold and captured Ada.

Leiden received city rights in 1266. In 1389, its population had grown to about 4,000 persons.

Siege of 1420

In 1420, during the Hook and Cod wars, Duke John III of Bavaria along with his army marched from Gouda in the direction of Leiden in order to conquer the city since Leiden did not pay the new Count of Holland Jacqueline, Countess of Hainaut, his niece and only daughter of Count William VI of Holland.

Burgrave Filips of Wassenaar and the other local noblemen of the Hook faction assumed that the duke would besiege Leiden first and send small units out to conquer the surrounding citadels. But John of Bavaria chose to attack the citadels first.

He rolled the cannons along with his army but one which was too heavy went by ship. By firing at the walls and gates with iron balls the citadels fell one by one. Within a week John of Bavaria conquered the castles of Poelgeest, Ter Does, Hoichmade, de Zijl, ter Waerd, Warmond and de Paddenpoel.

On 24 June the army appeared before the walls of Leiden. On 17 August 1420, after a two-month siege the city surrendered to John of Bavaria. The burgrave Filips of Wassenaar was stripped of his offices and rights and lived out his last years in captivity.

16th to 18th centuries

Relief of Leiden (1574), painting by Otto van Veen. Inundated meadows allow the Dutch fleet access to the Spanish infantry positions.

17th-century houses along the Herengracht

Town hall and bridge (de Koornbrug)

The 1852 Sijthoff printing office, Leiden

Leiden's west gate, the Morspoort

Leiden's east gate, the Zijlpoort

The Singel at night, showing the chimney of the Light Factory

Leiden flourished in the 16th and 17th century. At the close of the 15th century the weaving establishments (mainly broadcloth) of Leiden were very important. After the expulsion of the Spaniards, Leiden cloth, Leiden baize and Leiden camlet were familiar terms. In the same period, Leiden developed an important printing and publishing industry. The influential printer Christoffel Plantijn lived there at one time. One of his pupils was Lodewijk Elzevir (1547–1617), who established the largest bookshop and printing works in Leiden, a business continued by his descendants through 1712 and the name subsequently adopted (in a variant spelling) by contemporary publisher Elsevier.

In 1572, the city sided with the Dutch revolt against Spanish rule and played an important role in the Eighty Years' War. Besieged from May until October 1574 by the Spanish, Leiden was relieved by the cutting of the dikes, thus enabling ships to carry provisions to the inhabitants of the flooded town. As a reward for the heroic defence of the previous year, the University of Leiden was founded by William I of Orange in 1575. Yearly on 3 October, the end of the siege is still celebrated in Leiden. Tradition tells that the citizens were offered the choice between a university and a certain exemption from taxes and chose the university. The siege is notable also for being the first instance in Europe of the issuance of paper money, with paper taken from prayer books being stamped using coin dies when silver ran out.

Leiden is also known as the place where the Pilgrims (as well as some of the first settlers of New Amsterdam) lived (and operated a printing press) for a time in the early 17th century before their departure to Massachusetts and New Amsterdam in the New World.

In the 17th century, Leiden prospered, in part because of the impetus to the textile industry by refugees from Flanders. While the city had lost about a third of its 15,000 citizens during the siege of 1574, it quickly recovered to 45,000 inhabitants in 1622, and may have come near to 70,000 circa 1670. During the Dutch Golden Era, Leiden was the second largest city of Holland, after Amsterdam. Particularly due to the work by Herman Boerhaave (1668–1738), it played a crucial role in the establishment of modern chemistry and medicine.

From the late 17th century onwards Leiden slumped, mainly due to the decline of the cloth industries. In the beginning of the 19th century the baize manufacture was altogether given up, although industry remained central to Leiden economy. This decline is painted vividly by the fall in population. The population of Leiden had sunk to 30,000 between 1796 and 1811, and in 1904 was 56,044.

From the 17th to the early 19th century, Leiden was the publishing place of one of the most important contemporary journals, Nouvelles Extraordinaires de Divers Endroits, known also as Gazette de Leyde.

19th and 20th centuries

On 12 January 1807, a catastrophe struck the city when a boat loaded with 17,400 kilograms (38,360 pounds) of gunpowder blew up in the middle of Leiden. 151 people were killed, over 2,000 were injured and some 220 homes were destroyed. King Louis Bonaparte personally visited the city to provide assistance to the victims. Although located in the centre of the city, the area destroyed remained empty for many years. In 1886 the space was turned into a public park, the Van der Werff park.

In 1842, the railroad from Leiden to Haarlem was inaugurated and one year later the railway to Den Haag was completed, resulting in some social and economic improvement. Perhaps the most important piece of Dutch history contributed by Leiden was the Constitution of the Netherlands. Johan Rudolf Thorbecke (1798–1872) wrote the Dutch Constitution in April 1848 in his house at Garenmarkt 9 in Leiden.

Leiden's reputation as the "city of books" continued through the 19th century with the establishment of publishing dynasties by Evert Jan Brill and Albertus Willem Sijthoff. Sijthoff, who rose to prominence in the trade of translated books, wrote a letter in 1899 to Queen Wilhelmina regarding his opposition to becoming a signatory to the Berne Convention for the Protection of Literary and Artistic Works. He felt that international copyright restrictions would stifle the Dutch publishing industry.

Leiden grew 12-fold in size between 1896 and 1981, annexing land from neighboring municipalities

Leiden began to expand beyond its 17th-century moats around 1896 and the number of citizens surpassed 50,000 in 1900. After 1920, new industries were established in the city, such as the canning and metal industries. During World War II, Leiden was hit hard by Allied bombardments. The areas surrounding the railway station and Marewijk were almost completely destroyed.

Leiden today

The city's biggest and most popular annual festival is celebrated at 3 October and is called simply 3 Oktober. The people of Leiden celebrate the end of the Spanish siege of 1574. It typically takes place over the course of two to three days (usually two but three if there's a Sunday involved) and includes parades, a hutspot feast, historical reenactments, a funfair and other events. The city has recently started to host the Leiden International Film Festival, the fastest growing festival of its type in the Netherlands.

Leiden has important functions as a shopping and trade centre for communities around the city. The University of Leiden is famous for its many discoveries including Snells law (by Willebrord Snellius),

the famous Leyden jar, a capacitor made from a glass jar, invented in Leiden by Pieter van Musschenbroek in 1746. Another development was in cryogenics: Heike Kamerlingh Onnes (1913 Nobel prize winner in physics) liquefied helium for the first time (1908) and later managed to reach a temperature of less than one degree above the absolute minimum. Albert Einstein also spent some time at Leiden University during his early to middle career.

The city also houses the Eurotransplant, the international organization responsible for the mediation and allocation of organ donation procedures in Austria, Belgium, Croatia, Germany, Luxembourg, the Netherlands and Slovenia. Leiden also houses the headquarters of Airbus, a global pan-European aerospace and defence corporation and a leading defence and military contractor worldwide. The group includes Airbus, the leading manufacturer of commercial aircraft worldwide.

Rivers, canals and parks

Canal near Leiden - May 1978

The two branches of the Oude Rijn, which enter Leiden on the east, unite in the centre of the city. The city is further intersected by numerous small canals with tree-bordered quays. On the west side of the city, the Hortus Botanicus and other gardens extend along the old Singel, or outer canal. The Leidse Hout park, which contains a small deer park, lies on the northwest border with Oegstgeest. The Van der Werf Park is named after the mayor Pieter Adriaansz. van der Werff, who defended the city against the Spaniards in 1574. The city was beleaguered for months and many died from famine. The open space for the park was formed by the accidental explosion of a ship loaded with gunpowder in 1807, which destroyed hundreds of houses, including that of the Elsevier family of printers.

Buildings of interest

Because of the economic decline from the end of the 17th until the middle of the 19th century, much of the 16th- and 17th-century city centre is still intact. It is the second largest 17th-century town centre in the Netherlands, the largest being Amsterdam's city centre.

A hundred buildings in the centre are decorated with large murals of poetry, part of a wall poem project active from 1992, and still ongoing.

• Shakespeare
  on a Leiden wall

• Langston Hughes
  on a Leiden wall

• e.e. cummings

• Waring Cuney

Fortifications

At the strategically important junction of the two arms of the Oude Rijn stands the old castle de Burcht, a circular tower built on an earthen mound. The mound probably was a refuge against high water before a small wooden fortress was built on top of it in the 11th century. The citadel is a so-called motte-and-bailey castle. Of Leiden's old city gates only two are left, the Zijlpoort and the Morspoort, both dating from the end of the 17th century. Apart from one small watch tower on the Singel nothing is left of the town's city walls. Another former fortification is the Gravensteen. Built as a fortress in the 13th century it has since served as house, library and prison. Presently it is one of the University's buildings.

Churches

Hooglandse Kerk, Leiden

Church (de Sint Lodewijkskerk)

The chief of Leiden's numerous churches are the Hooglandse Kerk (or the church of St Pancras, built in the 15th century and containing a monument to Pieter Adriaansz. van der Werff) and the Pieterskerk (church of St Peter (1315)) with monuments to Scaliger, Boerhaave and other famous scholars. From a historical perspective the Marekerk is interesting too. Arent van 's Gravesande designed that church in 1639. Other fine examples of his work in Leiden are in the Stedelijk Museum De Lakenhal (the municipal museum of fine arts), and the Bibliotheca Thysiana. The growing city needed another church and the Marekerk was the first Protestant church to be built in Leiden (and in Holland) after the Reformation. It is an example of Dutch Classicism. In the drawings by Van 's Gravesande the pulpit is the centrepiece of the church. The pulpit is modelled after the one in the Nieuwe Kerk at Haarlem (designed by Jacob van Campen). The building was first used in 1650, and is still in use. The Heilige Lodewijkkerk is first catholic church in Leiden that was built after the Reformation. This church was given to the Catholics after the gunpowder explosion in 1807, which killed 150 inhabitants and destroyed a large part of the city centre. The 'Waalse Kerk' (Breestraat 63) was originally part of the Katharina Hospital. In 1584 it became the church of Protestant refugees from the Southern Netherlands (Brugge) and France. Later churches in the centre include the St. Joseph in expressionistic style.

University buildings

The 1860 Leiden Observatory, after restoration (2013)

The city centre contains many buildings that are in use by the University of Leiden. The Academy Building is housed in a former 16th-century convent. Among the institutions connected with the university are the national institution for East Indian languages, ethnology and geography; the botanical gardens, founded in 1587; the observatory (1860); the museum of antiquities (Rijksmuseum van Oudheden); and the ethnographical museum, of which P. F. von Siebold's Japanese collection was the nucleus (Rijksmuseum voor Volkenkunde). This collection is now housed in a separate museum called the SieboldHuis. The Bibliotheca Thysiana occupies an old Renaissance building of the year 1655. It is especially rich in legal works and vernacular chronicles. Noteworthy are also the many special collections at Leiden University Library among which those of the Society of Dutch Literature (1766) and the collection of casts and engravings. In recent years the university has built the Leiden Bio Science Park at the city's outskirts to accommodate the Science departments.

De Waag (1900)

Other buildings

• Stadhuis (City Hall), a 16th-century building that was badly damaged by a fire in 1929 but has its Renaissance façade designed by Lieven de Key still standing
• Gemeenlandshuis van Rijnland (1596, restored in 1878)
• De Waag (weigh house in Dutch), built by Pieter Post
• Gravensteen – a former 15th century jail at the Gerecht square (former court-house)
• Stedelijk Gymnasium (aka Latijnse School) – the old gymnasium (1599)
• Stadstimmerwerf – the city carpenter's yard and wharf (1612), both built by Lieven de Key (c. 1560–1627)
• Heilige Geest Weeshuis (a former Holy Spirit Orphanage) – a complex of 16th century buildings.
• Molen de Valk – a corn-grinding windmill, now home to a museum (1743)
• Pesthuis, which was built during 1657–1661 at that time just outside the city for curing patients suffering the bubonic plague. However, after it was built the feared disease did not occur in the Netherlands anymore so it was never used for its original purpose. The building has been used as a military hospital, prison, national asylum and army museum. It now serves as the entrance of Naturalis, one of the largest natural history museums in the world.

Public transport

Leiden, central railway station

Bus transport in Leiden is provided by Arriva.

Railway stations within the municipality of Leiden are:

• Leiden Centraal
• Leiden Lammenschans
• De Vink

Notable inhabitants

See also: Category:People from Leiden

The following is a selection of important Leidenaren throughout history:

William II, Count of Holland in the Lakenhal

Public thinking & Public Service

• William II, Count of Holland (1228–1256) Count of Holland 1234-1256
• Floris V, Count of Holland (1254–1296) Count of Holland and Zeeland 1256–1296.
• John of Leiden (1509–1536) leader of the Anabaptist Münster Rebellion
• William Brewster (1568–1644) pilgrim, Mayflower passenger in 1620
• Daniel Heinsius (1580–1655) a famous scholar of the Dutch Renaissance
• William Bradford (1590–1657) pilgrim, leader of the American Plymouth Colony in Massachusetts
• Franciscus Junius (1591–1677) a pioneer of Germanic philology
• Isaac Elzevir (1596–1651) a Dutch publisher and printer, co-founder of House of Elzevir
• Love Brewster (1611–1650/1) pilgrim and founder of Bridgewater, Massachusetts
• Isaac Vossius (1618–1689) a scholar, manuscript collector and Canon at Windsor Castle
• Nicolaas Heinsius the Elder (1620–1681) a Dutch classical scholar and poet
• Johann Bachstrom (1688–1742) writer, scientist and Lutheran theologian
• Gottfried, Freiherr van Swieten (1733-1803) diplomat, friend and patron of several great composers
• Jan Bake (1787–1864) a Dutch philologist and critic
• Reinhart Dozy (1820–1883) a Dutch scholar of Arabic of Huguenot origin
• Cornelis Tiele (1830–1902) a Dutch theologian and scholar
• J. P. B. de Josselin de Jong (1886–1964) a museum curator, founding father of modern Dutch anthropology and structural anthropology and an academic
• Hans de Koster (1914–1992) a Dutch politician, diplomat and businessman
• twins Alfred Kossmann (1922–1998) a poet and prose writer & Ernst Kossmann (1922–2003) an historian.
• Leendert Ginjaar (1928–2003) a Dutch politician and chemist
• Laurens Jan Brinkhorst (born 1937) a retired Dutch politician and diplomat
• Ankie Broekers-Knol (born 1946) a Dutch politician, jurist and Minister
• Carel Stolker (born 1954) is rector magnificus and president of Leiden University since 2013
• Princess Laurentien of the Netherlands (born 1966) the wife of Prince Constantijn
• Kajsa Ollongren (born 1967) a Dutch-Swedish politician, Deputy Prime Minister of the Netherlands
• Julius Terpstra (born 1989) a Dutch politician

The Arts

Rembrandt van Rijn, ca.1655

Willem van de Velde II, ca.1660)

Leoni Jansen, 2013

• Cornelis Engebrechtsz. (ca.1462–1527) an early Dutch painter
• Lucas van Leyden (1494–1533) a Dutch painter and printmaker in engraving and woodcut
• Jan van Goyen (1596–1656) a Dutch landscape painter
• Justus van Egmont (1601–1674) a painter and tapestry designer
• Rembrandt van Rijn (1606– 1669) a Dutch draughtsman, painter and printmaker
• Willem van de Velde the Elder (1610/11–1693) a Dutch Golden Age seascape painter
• Frans Post (1612–1680) a Dutch Golden Age painter
• Gerard Dou (1613–1675) a Dutch Golden Age painter
• Jan Steen (ca.1626–1679) a Dutch Golden Age genre painter
• Gabriel Metsu (1629–1667) painter of history paintings, still life, portraits and genre works
• Willem van de Velde the Younger (1633-1707) a Dutch marine painter
• Frans van Mieris the Elder (1635–1681) a Dutch Golden Age genre and portrait painter
• Jan Gaykema Jacobsz. (1798–1875) a Dutch painter, draughtsman and botanical illustrator
• Jan Elias Kikkert (1843–1925) a Dutch lithographer and watercolorist of street scenes of Leiden
• Coenraad V. Bos (1875–1955) a Dutch pianist, an accompanist to singers of lieder
• Theo van Doesburg (1883–1931) a Dutch artist, founder and leader of De Stijl
• Ernst Winar (1894–1978) a Dutch actor and film director
• Nina Foch (1924–2008) a Dutch American actress and drama teacher
• Michel Waisvisz (1949–2008) a Dutch composer, performer, inventor of experimental electronic musical instruments and artistic director of STEIM 1981-2008
• Leoni Jansen (born 1955) a TV personality and anchor-woman, singer and stage-director
• Daniel Reuss (born 1961) a Dutch conductor, primarily a choral conductor
• Isa Hoes (born 1967) a Dutch actress and voice actress
• Eva Dorrepaal (born 1970) a Dutch actress
• Armin van Buuren (born 1976) a Dutch DJ, record producer and remixer
• Carice van Houten (born 1976) a Dutch actress and singer
• Dyro (born 1992) a Dutch DJ and Electronic dance music producer

Science

Herman Boerhaave

Johannes Diderik van der Waals

• Charles de L'Écluse (1526–1609) botanist, horticulturist and director of Hortus Botanicus Leiden
• Ludolph van Ceulen (1540–1610) mathematician, computed the number π, Pi
• Willebrord Snellius (1580–1626) a Dutch astronomer and mathematician >
• Herman Boerhaave (1668–1738) a botanist, chemist, Christian humanist and physician
• Bernhard Siegfried Albinus (1697–1770) a German-born Dutch anatomist
• Gerard van Swieten (1700–1772) a Dutch physician, personal physician of Maria Theresa
• Petrus Camper FRS (1722–1789) a Dutch physician, anatomist, physiologist, midwife, zoologist, anthropologist, palaeontologist and a naturalist
• Philipp Franz von Siebold (1796–1866) a German physician and botanist, studied Japanese flora and fauna
• Johannes Diderik van der Waals (1837–1923) a Dutch theoretical physicist, winner of the 1910 Nobel prize in Physics
• Hendrik Lorentz (1853–1928) a Dutch physicist, joint winner of the 1902 Nobel Prize in Physics
• Heike Kamerlingh Onnes (1853–1926) a Dutch physicist and winner of the 1913 Nobel prize in Physics
• Willem Einthoven (1860–1927) a Dutch physician and physiologist
• Pieter Zeeman (1865–1943) a Dutch physicist, joint winner of the 1902 Nobel Prize in Physics
• Willem de Sitter (1872–1934) a Dutch mathematician, physicist and astronomer
• Albert Einstein (1879–1955) lecturer/researcher at Leiden University, variously between 1916 and 1930
• Paul Ehrenfest (1880–1933) an Austrian/Dutch theoretical physicist, contributed to statistical mechanics
• Geertruida de Haas-Lorentz (1885–1973) a female Dutch physicist, worked on Brownian motion and electrical noise theory
• Jan Oort (1900–1992) a Dutch astronomer, pioneer in radio astronomy
• Hendrik Casimir (1909–2000) a Dutch physicist
• Ewine van Dishoeck (born 1955) a Dutch astronomer, chemist, molecular astrophysicist and academic

Sport

Alfons Groenendijk, 2017

Kjeld Nuis, 2018

• Willem Slijkhuis (1923–2003) a Dutch middle distance runner, won two bronze medals in the 1948 Summer Olympics
• Sandra Le Poole (born 1959) a retired field hockey player, team gold medallist at the 1984 Summer Olympics
• Ronald Florijn (born 1961) a former rower, twice team gold medallist, at the 1988 and 1996 Summer Olympics
• Carina Benninga (born 1962) & Taco van den Honert (born 1966) former Dutch field hockey players, team gold medallist at the 1984 Summer Olympics and team bronze medallist at the 1988 Summer Olympics
• Alfons Groenendijk (born 1964) a former footballer with 413 club caps and current manager
• Gerritjan Eggenkamp (born 1975) a Dutch rower, team silver medallist at the 2004 Summer Olympics
• Rodney Glunder (born 1975) a retired kickboxer, mixed martial artist, professional wrestler and boxer
• Tim de Cler (born 1978) a Dutch former footballer with 361 club caps
• Erik van den Doel (born 1979) a Dutch chess Grandmaster
• Merel Witteveen (born 1985) a sailor, team silver medallist at the 2008 Summer Olympics
• Biurakn Hakhverdian (born 1985) & Iefke van Belkum (born 1986) Dutch water polo players, team gold medallist at the 2008 Summer Olympics
• Gegard Mousasi (born 1985) a Dutch mixed martial artist and former kickboxer
• Laurine van Riessen (born 1987) a long track speed skater and track cyclist, bronze medallist at the 2010 Winter Olympics
• Kjeld Nuis (born 1989) a Dutch speed skater, world record holder and gold medallist at the 2018 Winter Olympics over 1000 metre and 1500 metre

Buurtpoes Bledder

• Chantal de Ridder (born 1989) a Dutch football striker, 46 caps with the Netherlands women's national football team
• Esmee Visser (born 1996) a long distance speed skater, gold medallist in the 2018 Winter Olympics in the women's 5000 metres

Others

• Maria Swanenburg (1839–1915) a Dutch serial killer, murdered at least 27 people and suspected of killing more than 90
• Marinus van der Lubbe (1909–1934) executed for the Reichstag fire in Berlin in 1933
• Buurtpoes Bledder (2011–2013) a male domestic cat, media star for his exploits in the city

International relations

Twin cities – sister cities

Leiden is twinned with:

Buffalo City, Eastern Cape, South Africa Juigalpa, Chontales, Nicaragua Krefeld, North Rhine-Westphalia, Germany

Nagasaki, Japan Oxford, United Kingdom Toruń, Poland

Miscellaneous

Eastern gate 'Zijlpoort' at the Singel

• The coat of arms of Leiden is two red keys, crossed in an X-shape on a white background. These keys are the Keys of Heaven held by St. Peter, for whom a large church in the city centre is named. Because of this coat of arms, Leiden is referred to as the "Sleutelstad" ("the key city").
• For a time Leiden held the title "The Coldest Place on Earth" because of the developments in cryogenics in a laboratory there. Heike Kamerlingh Onnes (1913 Nobel prize winner in physics) liquefied helium for the first time (1908), and later managed to reach a temperature of less than one degree above Absolute zero.
• The Norwegian cheese "nøkkelost" ("key cheese") is named after the keys in coat of arms of Leyden, as it is a variation of Leyden cheese.
• The following places and things are named after this city:
  • Leyden, New York, USA
  • Leyden, Massachusetts, USA
  • Leyden High School District 212 in Franklin Park, Illinois, USA.
  • Leiden scale, for measuring extreme low temperatures.
  • Factor V Leiden is named after the city of Leiden where it was discovered in 1994.
  • The Leyden jar, a capacitor made from a glass jar, was invented here by Pieter van Musschenbroek in 1746. It was actually first invented by Ewald Georg von Kleist the year before, but the name "Leyden jar" stuck.
• Leiden's Stadhuis (Town Hall) has a poem in the form of a cryptogram on its façade that records the date 1574 in Roman numerals, the year of the "Black Famine" or Spanish siege (W equals two Vs):

The poem on Leiden's Stadhuis

Nae zWarte HVnger-noot
GebraCht had tot de doot
bInaest zes-dVIzent MensChen;

aLst god den heer Verdroot
gaf hI Vns Weder broot
zo VeeL WI CVnsten WensChen.

(Dutch: "When the Black Famine had brought to the death nearly six thousand persons, then God the Lord repented, and gave bread again as much as we could wish".)

Sports

• Zorg en Zekerheid Leiden is the basketball club of Leiden. In 2011 and 2013 they won the National Title, in 2010 and 2012 the National Cup and in 2011 and 2012 the National Super Cup. The club also played in the FIBA EuroChallenge and reached the Second Round (Best 16) in 2011/2012.

See also

• Leiden Classical A distributed computing project
• Oudt Leyden, former Michelin starred restaurant
• Wireless Leiden

References

Sources

• Lourens, Piet; Lucassen, Jan (1997). Inwonertallen van Nederlandse steden ca. 1300–1800. Amsterdam: NEHA. ISBN 9057420082.

Further reading

Further information: Bibliography of the history of Leiden

External links

• Chisholm, Hugh, ed. (1911). "Leiden" . Encyclopædia Britannica. 16 (11th ed.). Cambridge University Press.
• Official website
• Scenic video 'Leiden Sleutelstad' ('Leiden, city of keys') (time lapse)

UpToDate Contents

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• 1. 血友病の遺伝学 genetics of the hemophilias
• 2. 血友病の臨床症状および診断 clinical manifestations and diagnosis of hemophilia
• 3. 回虫症の肺症状 pulmonary manifestations of ascariasis
• 4. コカイン乱用の肺合併症 pulmonary complications of cocaine abuse
• 5. 肺好酸球増多症の原因 causes of pulmonary eosinophilia

English Journal

• Perspectives on the Etiology of Violence in Later Life.

• Mysyuk Y1, Westendorp RG2, Lindenberg J3.
• Journal of interpersonal violence.J Interpers Violence.2016 Nov;31(18):3039-3062. Epub 2015 May 8.
• This article focuses on the development of a conceptual framework for explaining the etiology of violence in later life by various groups involved in the field of elder abuse. In this study, we explore this through eight focus groups with different professionals involved in the field of elder abuse
• PMID 25957060

• Hemiplegic Shoulder Pain Reduces Quality of Life After Acute Stroke: A Prospective Population-Based Study.

• Adey-Wakeling Z1, Liu E, Crotty M, Leyden J, Kleinig T, Anderson CS, Newbury J.
• American journal of physical medicine & rehabilitation / Association of Academic Physiatrists.Am J Phys Med Rehabil.2016 Oct;95(10):758-63. doi: 10.1097/PHM.0000000000000496.
• OBJECTIVE: Hemiplegic shoulder pain is a common complication of stroke. The primary aim of this study was to determine the association of hemiplegic shoulder pain with health-related quality of life at 12 months after first stroke in a population-based registry. The secondary aim was to identify oth
• PMID 27003204

• Prediction of early mortality following hip fracture surgery in frail elderly: The Almelo Hip Fracture Score (AHFS).

• Nijmeijer WS1, Folbert EC2, Vermeer M3, Slaets JP4, Hegeman JH2.
• Injury.Injury.2016 Oct;47(10):2138-2143. doi: 10.1016/j.injury.2016.07.022. Epub 2016 Jul 20.
• BACKGROUND: Hip fractures are common in the elderly and have a high risk of early mortality. Identification of patients at high risk of early mortality could contribute to enhanced quality of care. A simple scoring system is essential for preoperative identification of patients at high risk of early
• PMID 27469403

Japanese Journal

• 気管支擦過細胞診にてアレルギー性気管支肺アスペルギルス症が疑われた 1 例

• 日本臨床細胞学会雑誌 54(3), 221-222, 2015
• NAID 130005078154

• Schizophyllum commune (スエヒロタケ)によるアレルギー性気管支肺真菌症の1例

• 日本臨床細胞学会雑誌 52(6), 583-588, 2013-11-22
• NAID 10031203535

• レンブラントとリューカス・ファン・レイデン : 「エッケ・ホモ」を中心に(第六十三回美学会全国大会発表要旨)

• 美學 63(2), 142, 2012-12-31
• NAID 110009578785

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