L-aspartyl-L-phenylalanine methyl ester

アスパルチルフェニルアラニンメチルエステル

WordNet

1. formed by reaction between an acid and an alcohol with elimination of water
2. the 12th letter of the Roman alphabet (同)l
3. an essential amino acid found in proteins and needed for growth of children and for protein metabolism in children and adults; abundant in milk and eggs; it is normally converted to tyrosine in the human body
4. the univalent radical CH3- derived from methane (同)methyl_group, methyl radical

PrepTutorEJDIC

1. エステル(酸とアルコールから水を分離してできる化合物の総称)
2. lira(イタリアの貨幣単位リラ)
3. liter[s]

UpToDate Contents

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English Journal

• Prooxidative effects of aspartame on antioxidant defense status in erythrocytes of rats.

• Prokic MD1, Paunovic MG, Matic MM, Djordjevic NZ, Ognjanovic BI, Stajn AS, Saicic ZS.
• Journal of biosciences.J Biosci.2014 Dec;39(5):859-66.
• Since aspartame (L-aspartyl-L-phenylalanine methyl ester, ASP) is one of the most widely used artificial sweeteners, the aim of the present study was to investigate its effects on serum glucose and lipid levels as well as its effects on oxidative/antioxidative status in erythrocytes of rats. The exp
• PMID 25431414

• Application of protein N-terminal amidase in enzymatic synthesis of dipeptides containing acidic amino acids specifically at the N-terminus.

• Arai T1, Noguchi A, Takano E, Kino K.
• Journal of bioscience and bioengineering.J Biosci Bioeng.2013 Apr;115(4):382-7. doi: 10.1016/j.jbiosc.2012.10.024. Epub 2012 Dec 4.
• Dipeptides exhibit unique physiological functions and physical properties, e.g., l-aspartyl-l-phenylalanine-methyl ester (Asp-Phe-OMe, aspartame) as an artificial sweetener, and functional studies of peptides have been carried out in various fields. Therefore, to establish a manufacturing process fo
• PMID 23218487

• Effects of site-directed mutagenesis of Asn116 in the β-hairpin of the N-terminal domain of thermolysin on its activity and stability.

• Menach E1, Yasukawa K, Inouye K.
• Journal of biochemistry.J Biochem.2012 Sep;152(3):231-9. doi: 10.1093/jb/mvs064. Epub 2012 May 29.
• In the N-terminal domain of thermolysin, two anti-parallel β-strands, Asn112-Ala113-Phe114-Trp115 and Ser118-Gln119-Met120-Val121-Tyr122 are connected by an Asn116-Gly117 turn to form a β-hairpin structure. In this study, we examined the role of Asn116 in the activity and stability of thermolysin
• PMID 22648563

Japanese Journal

• Application of protein N-terminal amidase in enzymatic synthesis of dipeptides containing acidic amino acids specifically at the N-terminus(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)

• Arai Toshinobu,Noguchi Atsushi,Takano Eriko [他],Kino Kuniki
• Journal of bioscience and bioengineering 115(4), 382-387, 2013-04
• … Dipeptides exhibit unique physiological functions and physical properties, e.g., L-aspartyl-L-phenylalanine-methyl ester (Asp-Phe-OMe, aspartame) as an artificial sweetener, and functional studies of peptides have been carried out in various fields. …
• NAID 110009603684

• Effects of Site-Directed Mutagenesis of the Loop Residue of the N-Terminal Domain Gly117 of Thermolysin on Its Catalytic Activity

• Menach Evans,Yasukawa Kiyoshi,Inouye Kuniyo
• Bioscience, biotechnology, and biochemistry 74(12), 2457-2462, 2010-12-23
• … G117E exhibited lower activity in the hydrolysis of N-[3-(2-furyl)acryloyl]-glycyl-L-leucine amide and higher activity in the hydrolysis of N-carbobenzoxy-L-aspartyl-L-phenylalanine methyl ester than the wild-type thermolysin. …
• NAID 10027728151

• Screening, purification, and identification of the enzyme producing N-(L-α-L-aspartyl)-L-phenylalanine methyl ester from L-isoasparagine and L-phenylalanine methyl ester(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)

• Kira Ikuo,Asano Yasuhisa,Yokozeki Kenzo
• Journal of bioscience and bioengineering 108(3), 190-193, 2009-09
• … Screening was carried out for microorganisms able to produce N-(L-α-L-aspartyl)-L-phenylalanine methyl ester [APM] from L-isoasparagine and L-phenylalanine methyl ester hydrochloride. …
• NAID 110007386280

Related Links

• N-L-α-アスパルチル-L-フェニルアラニン-1-メチルエステル ...

試薬名（別名） N-L-α-アスパルチル-L-フェニルアラニン-1-メチルエステル 英名 N-L-α-Aspartyl-L-phenylalanine-1-methyl ester 品番 10344-0415 ((M)SDS) CAS No. 22839-47 ...

• L-Aspartyl-L-phenylalanine methyl ester - Dietary supplement ...

Aspartame (L-alpha-aspartyl-L-phenylalanine methyl ester) is a low-calorie sweetener used to sweeten... ... Aspartame (L-alpha-aspartyl-L-phenylalanine methyl ester) is a low-calorie sweetener used to sweeten a wide variety of low ...

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★リンクテーブル★

リンク元	「アスパルチルフェニルアラニンメチルエステル」
関連記事	「L」「phenylalanine」

「アスパルチルフェニルアラニンメチルエステル」

　　[★]

英

L-aspartyl-L-phenylalanine methyl ester

関

アスパルテーム

「L」

　　[★]

• リシジン
• リンキング数
• ロイシン
• free ligand concentration

　 　

「phenylalanine」

　　[★] フェニルアラニン