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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/10 16:14:29」(JST)

Indolo[3,2-c]quinoline G-Quadruplex Stabilizers: a Structural Analysis of Binding to the Human Telomeric G-Quadruplex.

Lavrado J1, Ohnmacht SA, Correia I, Leitão C, Pisco S, Gunaratnam M, Moreira R, Neidle S, Santos DJ, Paulo A.
ChemMedChem.ChemMedChem.2015 May;10(5):836-49. doi: 10.1002/cmdc.201500067. Epub 2015 Mar 26.
A library of 5-methylindolo[3,2-c]quinolones (IQc) with various substitution patterns of alkyldiamine side chains were evaluated for G-quadruplex (G4) binding mode and efficiency. Fluorescence resonance energy transfer melting assays showed that IQcs with a positive charge in the heteroaromatic nucl
PMID 25820698

How to define a significant deviation from the expected internal quality control result.

Ceriotti F, Brugnoni D, Mattioli S.
Clinical chemistry and laboratory medicine : CCLM / FESCC.Clin Chem Lab Med.2015 May 1;53(6):913-8. doi: 10.1515/cclm-2014-1149.
BACKGROUND: Internal quality control (IQC) is an everyday practice described in several documents. Its planning requires the definition of quality goals and a documentation system able to provide alarms as soon as the goals are not reached. We propose the use of the uncertainty approach to develop a
PMID 25870962

Establishing a reference range for thrombin generation using a standard plasma significantly improves assay precision.

Bagot CN1, Leishman E2.
Thrombosis research.Thromb Res.2015 Apr 22. pii: S0049-3848(15)00192-9. doi: 10.1016/j.thromres.2015.04.020. [Epub ahead of print]
BACKGROUND: Thrombin generation is a global coagulation assay which appears to be an effective method for assessing the potential for an individual's plasma to coagulate. However for this assay to become accepted in routine clinical practice it requires standardization.OBJECTIVES: To establish a ref
PMID 25956288