English Journal

First ex vivo study demonstrating that (99m)Tc-NTP 15-5 radiotracer binds to human articular cartilage.

Cachin F, Boisgard S, Vidal A, Filaire M, Auzeloux P, Culot D, Askienazy S, Madelmont JC, Chezal JM, Miot-Noirault E.SourceNuclear Medicine Department, Jean Perrin Cancer Centre, Clermont-Ferrand, France, florent.cachin@cjp.fr.
European journal of nuclear medicine and molecular imaging.Eur J Nucl Med Mol Imaging.2011 Aug 4. [Epub ahead of print]
PURPOSE: Preclinical data pointed to (99m)Tc-NTP 15-5 as a good candidate for single photon emission computed tomography (SPECT) imaging of cartilaginous disease. We set out to investigate and quantify (99m)Tc-NTP 15-5 ex?vivo uptake by human articular cartilage relative to bone (99m)Tc-hydroxymeth
PMID 21814851

Shoulder surface temperature and bone scintigraphy findings in patients with rotator cuff tears.

Koike Y, Sano H, Kinjyo T, Imamura I, Masahiro O, Goto M, Ooyama M, Kita A, Itoi E.SourceDepartment of Orthopaedic Surgery, Japanese Red Cross Sendai Hospital, Yagiyama Honcyo, Taihaku-Ku, Sendai, Miyagi, Japan. yokoike@gmail.com
Upsala journal of medical sciences.Ups J Med Sci.2011 May;116(2):142-7. Epub 2011 Feb 16.
BACKGROUND: Complex regional pain syndrome (CRPS) is one of the serious complications after surgical treatment of a rotator cuff tear. Both a measurement of body surface temperature and bone scintigraphy have been used as diagnostic tools for the early phase of CRPS.Unfortunately, few studies have b
PMID 21323485

Japanese Journal

三浦頌太,小田島智
日本放射線技術學會雜誌 68(6), 697-703, 2012-06-20
… The doses in the anterior and lateral areas of the patients were measured following administration of 99mTc-hydroxymethyl enebisphosphonic acid (HMDP), 131I, 18F-fluoro-2-deoxy-d-glucose (18F-FDG), and 99mTc-galactosyl-human serum albumin-diethylenetriamine-pentaacetic acid (GSA). … L/A was 52% with 99mTc-HMDP, 51% with 131I, 58% with 18F-FDG, and 33% with 99mTc-GSA, and radiation doses were found to be reduced by approximately 50% when interaction with patients was from the lateral side rather than the anterior side. …
NAID 10030496593

齋藤享子,高橋康幸,嶋田博孝,有坂有紀子,樋口徹也,織内昇
群馬県立県民健康科学大学紀要 7, 75-82, 2012-03
… ファントムを独自に作成し,^<99m>Tc-HMDPの集積比(1:1.5)とHot rods サイズ(φ=4〜19mm)を変化させ検出性を確認した.次に健常例では,投与後30〜180分のSPECT撮像したMIP像と投与後180分のWhole body像の画質を比較した.さらに,乳がん患者17例につき集積部位の検出性を医師より視覚評価した.結果:MIP画像は4mmまで検出可能であった.健常例および臨床例では90分で^<99m>Tc-HMDPの集積が良好で,両画像の全ての所見 …
NAID 110008914259

小川数馬
薬学雑誌 132(10), 1151-1157, 2012
… 99mTc-HYNIC-HBP gave higher levels of radioactivity in bone than 99mTc-HMDP. … There was no significant difference in clearance from blood between 99mTc-HYNIC-HBP and 99mTc-HMDP. … Consequently, 99mTc-HYNIC-HBP showed a higher bone-to-blood ratio than 99mTc-HMDP. …
NAID 130001871977