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- Haemophilus ducreyi
WordNet
- the 8th letter of the Roman alphabet (同)h
PrepTutorEJDIC
- hydrogenの化学記号
- 鉛筆の硬度 / 《俗》heroin
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/07 10:19:57」(JST)
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| Haemophilus ducreyi |
|
| Photomicrograph of H. ducreyi |
| Scientific classification |
| Kingdom: |
Bacteria |
| Phylum: |
Proteobacteria |
| Class: |
Gamma Proteobacteria |
| Order: |
Pasteurellales |
| Family: |
Pasteurellaceae |
| Genus: |
Haemophilus |
| Species: |
H. ducreyi |
| Binomial name |
Haemophilus ducreyi
(Neveu-Lemaire 1921)
Bergey et al. 1923 |
Haemophilus ducreyi is a fastidious gram-negative coccobacillus causing the sexually transmitted disease chancroid, a major cause of genital ulceration in developing countries characterized by painful sores on the genitalia. Another early symptom is dark or light-green shears in excrement. Chancroid starts as an erythematous papular lesion that breaks down into a painful bleeding ulcer with a necrotic base and ragged edge.
H. ducreyi can be cultured on chocolate agar. It is best treated with a macrolide like azithromycin and a third-generation cephalosporin like ceftriaxone. H. ducreyi gram stain appears as "school of fish."
Contents
- 1 Pathogenesis
- 2 Diagnosis
- 3 See also
- 4 References
- 5 External Links
Pathogenesis
Haemophilus ducreyi is an opportunistic microorganism that infects its host by way of breaks in the skin or epidermis. Inflammation then takes place as the area of infection is inundated with lymphocytes, macrophages, and granulocytes. This pyrogenic inflammation causes regional lymphadenitis in the sexually transmitted bacillus chancroid.[1]
Diagnosis
Although antigen detection, serology, and genetic amplification methods are sometimes used to diagnose infections with H. ducreyi and the genetic tests have greater sensitivity, they are not widely available, so cultures are currently considered the "gold standard" test.[2]
See also
- Sexually transmitted disease
References
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1256. ISBN 1-4160-2999-0.
- ^ Alfa, Michelle (2005). "The laboratory diagnosis of Haemophilus ducreyi". Canadian Journal of Infectious Disease & Medicine Microbiology 16 (1): 34–35. PMC 2095004. PMID 18159525.
External Links
- "Haemophilus ducreyi". NCBI Taxonomy Browser. 730.
- Infectious diseases
- Bacterial disease: Proteobacterial G−
- primarily A00–A79, 001–041, 080–109
|
|
| α |
| Rickettsiales |
Rickettsiaceae/
(Rickettsioses) |
| Typhus |
- Rickettsia typhi
- Rickettsia prowazekii
- Epidemic typhus, Brill–Zinsser disease, Flying squirrel typhus
|
|
Spotted
fever |
| Tick-borne |
- Rickettsia rickettsii
- Rocky Mountain spotted fever
- Rickettsia conorii
- Rickettsia japonica
- Rickettsia sibirica
- Rickettsia australis
- Rickettsia honei
- Flinders Island spotted fever
- Rickettsia africae
- Rickettsia parkeri
- Rickettsia aeschlimannii
- Rickettsia aeschlimannii infection
|
|
| Mite-borne |
- Rickettsia akari
- Orientia tsutsugamushi
|
|
| Flea-borne |
|
|
|
|
| Anaplasmataceae |
- Ehrlichiosis: Anaplasma phagocytophilum
- Human granulocytic anaplasmosis, Anaplasmosis
- Ehrlichia chaffeensis
- Human monocytotropic ehrlichiosis
- Ehrlichia ewingii
- Ehrlichiosis ewingii infection
|
|
|
| Rhizobiales |
| Brucellaceae |
|
|
| Bartonellaceae |
- Bartonellosis: Bartonella henselae
- Bartonella quintana
- either henselae or quintana
- Bartonella bacilliformis
- Carrion's disease, Verruga peruana
|
|
|
|
| β |
| Neisseriales |
| M+ |
- Neisseria meningitidis/meningococcus
- Meningococcal disease, Waterhouse–Friderichsen syndrome, Meningococcal septicaemia
|
|
| M- |
- Neisseria gonorrhoeae/gonococcus
|
|
| ungrouped: |
- Eikenella corrodens/Kingella kingae
- Chromobacterium violaceum
- Chromobacteriosis infection
|
|
|
| Burkholderiales |
- Burkholderia pseudomallei
- Burkholderia mallei
- Burkholderia cepacia complex
- Bordetella pertussis/Bordetella parapertussis
|
|
|
| γ |
Enterobacteriales
(OX-) |
| Lac+ |
- Klebsiella pneumoniae
- Rhinoscleroma, Klebsiella pneumonia
- Klebsiella granulomatis
- Klebsiella oxytoca
- Escherichia coli: Enterotoxigenic
- Enteroinvasive
- Enterohemorrhagic
- O157:H7
- O104:H4
- Hemolytic-uremic syndrome
- Enterobacter aerogenes/Enterobacter cloacae
|
|
| Slow/weak |
- Serratia marcescens
- Citrobacter koseri/Citrobacter freundii
|
|
| Lac- |
| H2S+ |
- Salmonella enterica
- Typhoid fever, Paratyphoid fever, Salmonellosis
|
|
| H2S- |
- Shigella dysenteriae/sonnei/flexneri/boydii
- Shigellosis, Bacillary dysentery
- Proteus mirabilis/Proteus vulgaris
- Yersinia pestis
- Yersinia enterocolitica
- Yersinia pseudotuberculosis
- Far East scarlet-like fever
|
|
|
|
| Pasteurellales |
| Haemophilus: |
- H. influenzae
- Haemophilus meningitis
- Brazilian purpuric fever
- H. ducreyi
- H. parainfluenzae
|
|
| Pasteurella multocida |
- Pasteurellosis
- Actinobacillus
|
|
| Aggregatibacter actinomycetemcomitans |
|
|
|
| Legionellales |
- Legionella pneumophila/Legionella longbeachae
- Coxiella burnetii
|
|
| Thiotrichales |
|
|
| Vibrionaceae |
- Vibrio cholerae
- Vibrio vulnificus
- Vibrio parahaemolyticus
- Vibrio alginolyticus
- Plesiomonas shigelloides
|
|
| Pseudomonadales |
- Pseudomonas aeruginosa
- Moraxella catarrhalis
- Acinetobacter baumannii
|
|
| Xanthomonadaceae |
- Stenotrophomonas maltophilia
|
|
| Cardiobacteriaceae |
|
|
| Aeromonadales |
- Aeromonas hydrophila/Aeromonas veronii
|
|
|
| ε |
| Campylobacterales |
- Campylobacter jejuni
- Campylobacteriosis, Guillain–Barré syndrome
- Helicobacter pylori
- Peptic ulcer, MALT lymphoma, Gastric cancer
- Helicobacter cinaedi
|
|
|
|
Index of bacterial disease
|
|
| Description |
|
|
| Disease |
- Gram-positive firmicutes
- Gram-positive actinobacteria
- Gram-negative proteobacteria
- Gram-negative non-proteobacteria
- Cholera
- Tuberculosis
|
|
| Treatment |
- Antibiotics
- cell wall
- nucleic acid
- mycobacteria
- protein synthesis
- other
- Antibodies
|
|
|
UpToDate Contents
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- 1. 軟性下疳 chancroid
- 2. 性器潰瘍患者へのアプローチ approach to the patient with genital ulcers
- 3. 性感染症の予防 prevention of sexually transmitted infections
- 4. 外陰部病変：形態に基づく鑑別診断 vulvar lesions differential diagnosis based on morphology
- 5. リンパ肉芽腫性病 lymphogranuloma venereum
English Journal
- Defining Potential Vaccine Targets of Haemophilus ducreyi Trimeric Autotransporter Adhesin DsrA.
- Fusco WG1, Choudhary NR, Stewart SM, Alam SM, Sempowski GD, Elkins C, Leduc I.
- Monoclonal antibodies in immunodiagnosis and immunotherapy.Monoclon Antib Immunodiagn Immunother.2015 Apr;34(2):73-82. doi: 10.1089/mab.2014.0054.
- Haemophilus ducreyi is the causative agent of the sexually transmitted genital ulcer disease chancroid. Strains of H. ducreyi are grouped in two classes (I and II) based on genotypic and phenotypic differences, including those found in DsrA, an outer membrane protein belonging to the family of multi
- PMID 25897604
- Mass treatment with single-dose azithromycin for yaws.
- Mitjà O1, Houinei W, Moses P, Kapa A, Paru R, Hays R, Lukehart S, Godornes C, Bieb SV, Grice T, Siba P, Mabey D, Sanz S, Alonso PL, Asiedu K, Bassat Q.
- The New England journal of medicine.N Engl J Med.2015 Feb 19;372(8):703-10. doi: 10.1056/NEJMoa1408586.
- BACKGROUND: Mass treatment with azithromycin is a central component of the new World Health Organization (WHO) strategy to eradicate yaws. Empirical data on the effectiveness of the strategy are required as a prerequisite for worldwide implementation of the plan.METHODS: We performed repeated clinic
- PMID 25693010
- A cross-sectional study of 'yaws' in districts of Ghana which have previously undertaken azithromycin mass drug administration for trachoma control.
- Ghinai R1, El-Duah P2, Chi KH3, Pillay A3, Solomon AW4, Bailey RL4, Agana N5, Mabey DC4, Chen CY3, Adu-Sarkodie Y2, Marks M4.
- PLoS neglected tropical diseases.PLoS Negl Trop Dis.2015 Jan 29;9(1):e0003496. doi: 10.1371/journal.pntd.0003496. eCollection 2015.
- Yaws, caused by Treponema pallidum ssp. pertenue, is reportedly endemic in Ghana. Mass distribution of azithromycin is now the cornerstone of the WHO yaws eradication campaign. Mass distribution of azithromycin at a lower target dose was previously undertaken in two regions of Ghana for the control
- PMID 25632942
Japanese Journal
- A CdtA-CdtC complex can block killing of HeLa cells by Haemophilus ducreyi cytolethal distending toxin
- The Haemophilus ducreyi cytolethal distending toxin induces DNA double-strand breaks and promotes ATM-dependent activation of RhoA
- The cytolethal distending toxin of Haemophilus ducreyi inhibits endothelial cell proliferation
Related Links
- "This photograph shows that a chancroid infection has spread to the inguinal lymph nodes, which have enlarged forming buboes. Caused by the sexually transmitted bacterium, Haemophilus ducreyi, in about half of the untreated ...
- The surveillance of antimicrobial susceptibility in H. ducreyi is complicated by the technical difficulties of performing sensitivity testing. Data are available from very few centres. H. ducreyi has developed resistance to a number of different antibiotics but with the exception of two strains isolated ...
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