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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/12/04 02:20:59」(JST)
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| Systematic (IUPAC) name | |
|---|---|
| 6α,9-difluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone,21-acetate | |
| Clinical data | |
| Trade names | Lidex |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| MedlinePlus | a601054 |
| Pregnancy cat. |
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| Legal status |
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| Routes | topical |
| Pharmacokinetic data | |
| Metabolism | hepatic |
| Identifiers | |
| CAS number | 356-12-7 Y |
| ATC code | C05AA11 D07AC08 |
| PubChem | CID 9642 |
| DrugBank | DB01047 |
| ChemSpider | 9265 Y |
| UNII | 2W4A77YPAN Y |
| KEGG | D00325 Y |
| ChEMBL | CHEMBL1501 Y |
| Chemical data | |
| Formula | C26H32F2O7 |
| Mol. mass | 494.525 g/mol |
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| Y (what is this?) (verify) | |
Fluocinonide (Fluonex, Lidex, Lidex-E, Lonide, Lyderm, and Vanos)[1] is a potent glucocorticoid steroid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort.
The usual prescription concentration is 0.05% as a topical cream, ointment, or gel. The application area should normally not be covered after application. In certain cases, the physician may recommend the use of an occlusive dressing after application to increase the rate and depth of absorption. The frequency of application depends on the condition being treated and the area affected, but most often it should be applied 2 to 4 times a day.[2]
Fluocinonide ranks as a "high-potency" (second-highest rank) topical corticosteroid. Minimal amounts should be used for a minimal length of time to avoid the occurrence of adverse effects.[medical citation needed]. Fluocinonide should not be used more than two times a day, though usually one application per day is sufficient [3]
Fluocinonide should not be used if infection is present. It should not be applied to the eyes or to sensitive areas such as the genitals or anus.[medical citation needed]
A common potential adverse effect is skin atrophy (thinning of the skin). Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal axis (HPA) suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.
Fluocinonide should be used with caution when treating children, pregnant women, nursing mothers, and anyone using the medication for longer than two weeks.
Fluocinonide is used in veterinary medicine. It is a treatment for allergies in dogs.[4] Natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure.[5]
References
- ^ MedlinePlus Drug Information: Fluocinonide Topical
- ^ "Fluocinonide Topical". MedlinePlus. US National Library of Medicine, NIH. Retrieved 6 March 2014.
- ^ Template:BNF 64, British National Formulary, September 2012
- ^ Dog Allergies www.squidoo.com/dogallergy
- ^ Zenoble RD, Kemppainen RJ . (1987-09-15). "Adrenocortical suppression by topically applied corticosteroids in healthy dogs". J Am Vet Med Assoc 191 (6): 685–8. PMID 2824410.
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Related Links
- fluocinonide (redirected from Fluonex) Also found in: Dictionary, Wikipedia. Related to Fluonex: fluocinonide, Lidex fluocinonide [floo″o-sin´o-nīd] a synthetic corticosteroid used topically for the relief of inflammation and pruritus in ...
- Find patient medical information for Fluonex topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis ...
Related Pictures
★リンクテーブル★
| リンク元 | 「フルオシノニド」 |
「フルオシノニド」
- 合成副腎皮質ホルモン剤の外用薬
- 糖質コルチコイド;強力な抗炎症作用;外用