- 関
- Fusobacterium nucleatum
WordNet
- the 6th letter of the Roman alphabet (同)f
PrepTutorEJDIC
- farad / forte
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/20 14:51:53」(JST)
[Wiki en表示]
| Fusobacterium nucleatum |
| Scientific classification |
| Domain: |
Bacteria |
| Phylum: |
Fusobacteria |
| Order: |
Fusobacteriales |
| Family: |
Fusobacteriaceae |
| Genus: |
Fusobacterium |
| Species: |
F. nucleatum |
Fusobacterium nucleatum is an oral bacterium, indigenous to the human oral cavity, that plays a role in periodontal disease. This organism is commonly recovered from different monomicrobial and mixed infections in humans and animals. It is a key component of periodontal plaque due to its abundance and its ability to coaggregate with other species in the oral cavity.[1][2]
See also: Chronic periodontitis
Contents
- 1 Preterm Births
- 2 Colonic Adenomas
- 3 See also
- 4 References
Preterm Births
Research implicates periodontal disease caused by F. nucleatum with preterm births in humans. In many studies, F. nucleatum cells have been isolated from the amniotic fluid, placenta, and chorioamnionic membranes of women delivering prematurely. Moreover, laboratory mice inoculated with F. nucleatum have been found to deliver prematurely, and the pathology of the infection seems to mirror observations in humans.[3] Together, this research provides strong evidence for a causal connection between F. nucleatum-caused periodontal disease and at least some cases of preterm delivery.
Colonic Adenomas
F. nucleatum has a demonstrated association with colon cancer; in addition, a mechanism has been described by which F. nucleatum induces tumor growth without the more general mechanism of inducing inflammation or otherwise irritating the colon tissue. This suggests direct and specific carcinogenesis.[4]
See also
- List of bacterial vaginosis microbiota
References
- ^ Kapatral V et al. (2002). "Genome sequence and analysis of the oral bacterium 'Fusobacterium nucleatum' strain ATCC 25586.". J Bacteriol 184 (7): 2005–2018. doi:10.1128/JB.184.7.2005-2018.2002. PMC 134920. PMID 11889109.
- ^ Signat B et al. (2011). "Fusobacterium nucleatum in Periodontal Health and Disease". Curr Iss Mol Biol 13 (2): 25–36.
- ^ http://iai.asm.org/cgi/content/short/72/4/2272
- ^ Kostic, AD; Chun, E; Robertson, L; Glickman, JN; Gallini, CA; Michaud, M; Clancy, TE; Chung, DC; Lochhead, P; Hold, GL; El-Omar, EM; Brenner, D; Fuchs, CS; Meyerson, M; Garrett, WS (Aug 14, 2013). "Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment.". Cell host & microbe 14 (2): 207–15. doi:10.1016/j.chom.2013.07.007. PMID 23954159.
- Infectious diseases
- Bacterial diseases: BV4 non-proteobacterial G- (primarily A00–A79, 001–041, 080–109)
|
|
| Spirochaete |
| Spirochaetaceae |
| Treponema |
- Treponema pallidum
- Treponema carateum (Pinta)
- Treponema denticola
|
|
| Borrelia |
- Borrelia burgdorferi/Borrelia afzelii
- Lyme disease
- Erythema chronicum migrans
- Neuroborreliosis
- Borrelia recurrentis (Louse borne relapsing fever)
- Borrelia hermsii/Borrelia duttoni/Borrelia parkeri (Tick borne relapsing fever)
|
|
|
| Leptospiraceae |
| Leptospira |
- Leptospira interrogans (Leptospirosis)
|
|
|
| Spirillaceae |
| Spirillum |
- Spirillum minus (Rat-bite fever/Sodoku)
|
|
|
|
| Chlamydiaceae |
| Chlamydophila |
- Chlamydophila psittaci (Psittacosis)
- Chlamydophila pneumoniae
|
|
| Chlamydia |
- Chlamydia trachomatis
- Chlamydia
- Lymphogranuloma venereum
- Trachoma
|
|
|
| Bacteroidetes |
- Bacteroides fragilis
- Tannerella forsythia
- Capnocytophaga canimorsus
- Porphyromonas gingivalis
- Prevotella intermedia
|
|
| Fusobacteria |
- Fusobacterium necrophorum (Lemierre's syndrome)
- Fusobacterium nucleatum
- Fusobacterium polymorphum
- Streptobacillus moniliformis (Rat-bite fever/Haverhill fever)
|
|
|
Index of bacterial disease
|
|
| Description |
|
|
| Disease |
- Gram-positive firmicutes
- Gram-positive actinobacteria
- Gram-negative proteobacteria
- Gram-negative non-proteobacteria
- Cholera
- Tuberculosis
|
|
| Treatment |
- Antibiotics
- cell wall
- nucleic acid
- mycobacteria
- protein synthesis
- other
- Antibodies
|
|
|
UpToDate Contents
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English Journal
- Quantitative analysis of microbiota in saliva, supragingival, and subgingival plaque of Chinese adults with chronic periodontitis.
- He J, Huang W, Pan Z, Cui H, Qi G, Zhou X, Chen H.SourceInstitute of Biotechnology, Zhejiang University, Hangzhou, China.
- Clinical oral investigations.Clin Oral Investig.2011 Dec 16. [Epub ahead of print]
- OBJECTIVE: The aim of this study was to determine the profiles of periodontopathogenic bacteria in a Chinese population using quantitative real-time polymerase chain reaction (qRT-PCR).MATERIALS AND METHODS: Twenty-four periodontally healthy Chinese subjects and 60 patients with chronic periodontiti
- PMID 22169888
- The adhesion of oral bacteria to modified titanium surfaces: role of plasma proteins and electrostatic forces.
- Badihi Hauslich L, Sela MN, Steinberg D, Rosen G, Kohavi D.SourceOral Microbiology and Ecology Lab, Betty and Walter Cohen Chair for Periodontal Research, The Hebrew, Jerusalem, Israel.
- Clinical oral implants research.Clin Oral Implants Res.2011 Dec 13. doi: 10.1111/j.1600-0501.2011.02364.x. [Epub ahead of print]
- OBJECTIVES: Modifications of titanium (Ti) implant surfaces have a significant effect on early biofilm formation and the outcome of implant procedures. The aim of this study was to examine the role of plasma proteins and electrostatic forces in the adhesion mechanism of oral bacteria to modified Ti
- PMID 22150723
Japanese Journal
- 文献と臨床の橋わたし 歯周病とがん(第2回)Fusobacterium nucleatumと大腸癌
- A-8 フィチン酸含有試作セメントの細菌増殖抑制効果(セメント,一般講演(口頭発表),第63回日本歯科理工学会学術講演会)
- 笹本 洋平,建部 二三,遠藤 一彦,越智 守生
- 日本歯科理工学会誌 33(2), 90, 2014-03-25
- … nucleatum. …
- NAID 110009815429
- Prevotella intermedia Induces Severe Bacteremic Pneumococcal Pneumonia in Mice with Upregulated Platelet-Activating Factor Receptor Expression
- Nagaoka Kentaro,Yanagihara Katsunori,Morinaga Yoshitomo,Nakamura Shigeki,Harada Tatsuhiko,Hasegawa Hiroo,Izumikawa Koichi,Ishimatsu Yuji,Kakeya Hiroshi,Nishimura Masaharu,Kohno Shigeru
- Infection and Immunity 82(2), 587-593, 2014-02
- … Similar effects were not observed in the supernatants of Porphyromonas gingivalis or Fusobacterium nucleatum. …
- NAID 120005439024
Related Links
- 株の内訳を菌種レベルで見ると，F. nucleatum 80 株，F. necrophorum 18株，Fusobacterium varium 5 株，Fusobacterium mortiferum 4株，Fusobacterium 24 川村千鶴子他 感染症学雑誌 第76巻 第1号 Table 1 Fusobacterium ...
- め，F.nucleatumとPrevotella菌株のAI-2産生につ いて，VibrioharveyiBB170の発光量をMicrotech-Nichion社のAuto-LUMI-counterで測定して調べ た。AI-2産生は，菌株によって違いがあるもののいず れの供試菌株にも認めた。しかし ...
- Oral infections F. nucleatum is one of the most abundant species in the oral cavity, in both diseased and healthy individuals [7–10]. It is implicated in various forms of periodontal diseases including the mild reversible form of gingivitis ...
★リンクテーブル★
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フソバクテリウム・ヌクレアタム、フゾバクテリウム・ヌクレアタム
- 関
- F. nucleatum
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- ラ
- Fusobacterium nucleatum、F. nucleatum
- 関
- フゾバクテリウム・ヌクレアタム
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フェニルアラニン phenylalanine
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