WordNet

any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
a Spanish courtesy title or form of address for a woman; "Dona Marguerita"
United States pathologist (born in Austria) who discovered human blood groups (1868-1943) (同)Karl Landsteiner

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1. 寒冷凝集素症 cold agglutinin disease
2. 赤血球抗原および抗体 red blood cell antigens and antibodies
3. 発作性寒冷血色素尿症 paroxysmal cold hemoglobinuria
4. 自己免疫性溶血性貧血の病因：寒冷凝集素症 pathogenesis of autoimmune hemolytic anemia cold agglutinin disease
5. 自己免疫性溶血性貧血の病因：温暖凝集素と薬剤 pathogenesis of autoimmune hemolytic anemia warm agglutinins and drugs

Whipple NS1, Moreau DA2, Moulds JM3, Hankins JS1, Wang WC1, Nottage KA1.
Pediatric blood & cancer.Pediatr Blood Cancer.2015 Nov;62(11):2044-6. doi: 10.1002/pbc.25591. Epub 2015 Jun 5.
Paroxysmal cold hemoglobinuria (PCH) is an autoimmune hemolytic anemia (AIHA) characterized by the presence of a Donath-Landsteiner (D-L) antibody. PCH occurs most commonly in young children and is associated with acute, often self-limited hemolytic anemia. The D-L antibody is classically a biphasic
PMID 26053459

Akpoguma AO1, Carlisle TL1, Lentz SR1.
BMC hematology.BMC Hematol.2015 Feb 13;15:3. doi: 10.1186/s12878-015-0023-7. eCollection 2015.
BACKGROUND: Paroxysmal cold hemoglobinuria is caused by a biphasic IgG autoantibody that triggers complement-mediated intravascular hemolysis. Paroxysmal cold hemoglobinuria has not previously been reported to occur in association with pregnancy.CASE PRESENTATION: We report a case of an 18 year old
PMID 25699184

Slemp SN1, Davisson SM2, Slayten J2, Cipkala DA3, Waxman DA4.
Laboratory medicine.Lab Med.2014 Summer;45(3):253-8; quiz e92. doi: 10.1309/LMWD51B2KIFSBLBJ.
Paroxysmal cold hemoglobinuria (PCH) is an acquired hemolytic anemia caused by immunoglobulin G (IgG) antibodies that sensitize red blood cells (RBCs) at cold temperatures by fixing complement to the RBCs causing intravascular hemolysis on rewarming. PCH usually appears in young children as recurren
PMID 25051079

横山智央,宮澤啓介,須永和代,鈴木茂,田野倉ちずる,日ヶ久保利昭,西里吉則,福武勝幸,大屋敷一馬
臨床血液 44(6), 375-380, 2003
… 直接・間接Coombs試験陽性，Donath-Landsteiner抗体は寒冷凝集素価高値のため，当初は偽陽性を示したが，その後，抗I自己抗体による寒冷凝集素症(CAD)と診断した。 …
NAID 130004500855

三島清司,岩田由守,柴田宏,益田順一
日本輸血学会雑誌 47(3), 390-394, 2001
… Testing for Donath-Landsteiner antibody proved negative and cold hemagglutinin test was normal. … DAT became negative concomitantly with the recovery from anemia and muscle weakness.The absorption of purified GM3 resulted in remarkably weak reactivity, indicating the affinity of anti-GM3 antibody with the erythrocyte membrane in this patient. …
NAID 130003707025