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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/06/23 09:32:41」(JST)

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Controlled porosity osmotic pump system for the delivery of diclofenac sodium: in-vitro and in-vivo evaluation.

Emara LH1, Taha NF, El-Ashmawy AA, Raslan HM, Mursi NM.
Pharmaceutical development and technology.Pharm Dev Technol.2014 Sep;19(6):681-91. doi: 10.3109/10837450.2013.823990.
The objective of this study was to develop controlled porosity osmotic pump (CPOP) tablets of diclofenac sodium (DS). The influence of different cores (polymers and osmogens) and coats (thickness and porosigen content) on DS release were studied. Results revealed that decreasing HPMC viscosity grade
PMID 24320694

Adoption of polymeric micelles to enhance the oral bioavailability of dexibuprofen: formulation, in-vitro evaluation and in-vivo pharmacokinetic study in healthy human volunteers.

Abdelbary G1, Makhlouf A.
Pharmaceutical development and technology.Pharm Dev Technol.2014 Sep;19(6):717-27. doi: 10.3109/10837450.2013.823994. Epub 2013 Aug 13.
This work aimed to incorporate Dexibuprofen (DXI), the pharmacologically active and more potent form of ibuprofen, into polymeric micelles based tablets with enhanced oral bioavailability. Thin film hydration technique was employed to prepare DXI polymeric micelles using Pluronic® F127 and/or P123
PMID 23937590

Novel delivery approach for ketotifen fumarate: dissofilms formulation using 3² experimental design: in vitro/in vivo evaluation.

Fahmy RH1, Badr-Eldin SM.
Pharmaceutical development and technology.Pharm Dev Technol.2014 Aug;19(5):521-30. doi: 10.3109/10837450.2013.800108. Epub 2013 May 28.
Orally dissolving films (dissofilms) have gained increasing popularity and attention due to their ease of administration and avoidance of first pass metabolism. Ketotifen fumarate (KF) bioavailability is reported to be only ~ 50% due to hepatic first-pass metabolism. Aiming to surmount this drawback
PMID 23713715