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intelligent somewhat arboreal ape of equatorial African forests (同)chimp, Pan_troglodytes

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Identification and functional comparison of seven-transmembrane G-protein-coupled BILF1 receptors in recently discovered nonhuman primate lymphocryptoviruses.

Spiess K1, Fares S2, Sparre-Ulrich AH2, Hilgenberg E3, Jarvis MA4, Ehlers B3, Rosenkilde MM5.
Journal of virology.J Virol.2015 Feb;89(4):2253-67. doi: 10.1128/JVI.02716-14. Epub 2014 Dec 10.
Coevolution of herpesviruses with their respective host has resulted in a delicate balance between virus-encoded immune evasion mechanisms and host antiviral immunity. BILF1 encoded by human Epstein-Barr virus (EBV) is a 7-transmembrane (7TM) G-protein-coupled receptor (GPCR) with multiple immunomod
PMID 25505061

African great apes are naturally infected with roseoloviruses closely related to human herpesvirus 7.

Lavergne A1, Donato D1, Gessain A2, Niphuis H3, Nerrienet E4, Verschoor EJ3, Lacoste V5.
Journal of virology.J Virol.2014 Nov;88(22):13212-20. doi: 10.1128/JVI.01490-14. Epub 2014 Sep 3.
Primates are naturally infected with herpesviruses. During the last 15 years, the search for homologues of human herpesviruses in nonhuman primates allowed the identification of numerous viruses belonging to the different herpesvirus subfamilies and genera. No simian homologue of human herpesvirus 7
PMID 25187544

The effect of adjuvanting cancer vaccines with herpes simplex virus glycoprotein D on melanoma-driven CD8+ T cell exhaustion.

Zhang Y1, Ertl HC2.
Journal of immunology (Baltimore, Md. : 1950).J Immunol.2014 Aug 15;193(4):1836-46. doi: 10.4049/jimmunol.1302029. Epub 2014 Jul 14.
Two vaccines expressing CD4(+) and CD8(+) T cell epitopes of melanoma-associated Ags (MAAs) by a chimpanzee-derived replication-defective AdC68 vector were compared in a mouse model of melanoma. In one vaccine, termed AdC68-gDMelapoly, the epitopes were expressed as a fusion protein within HSV-1 gly
PMID 25024391