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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/10/22 15:06:48」(JST)
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- Effects of periodontal afferent inputs on corticomotor excitability in humans.
- Zhang Y1, Boudreau S, Wang M, Wang K, Sessle B, Arendt-Nielsen L, Svensson P.Author information 1Department of Anatomy & Physiology, School of Stomatology, The Fourth Military Medical University, Xi'an, China.AbstractThe aim of the present study was to determine in humans whether local anaesthesia (LA) or nociceptive stimulation of the periodontal ligaments affects the excitability of the face primary motor cortex (MI) related to the tongue and jaw muscles, as measured by transcranial magnetic stimulation (TMS). Twelve healthy volunteers (11 men, 1 woman, 25.3 +/- 4.2 years) participated in two 3-h sessions separated by 7 days. The LA carbocain or the nociceptive irritant capsaicin was randomly injected into the periodontal ligament of the lower right central incisor. In both sessions, TMS-motor evoked potential (MEP) stimulus-response curves and corticomotor maps were acquired for the tongue and masseter muscles before (baseline) and at 5, 30 and 60 min post-application of carbocain or capsaicin. Transcranial magnetic stimulation-MEP stimulus-response curves were also acquired at these time points for the first dorsal interosseous (FDI) as an internal control. Burning pain intensity and mechanical sensitivity ratings to a von Frey filament applied to the application site were recorded on an electronic visual analogue scale (VAS). All subjects reported a decreased mechanical sensitivity (anova: P = 0.004) in the LA session and a burning pain sensation (VAS peak pain: 6.4 +/- 1.0) in the capsaicin session. No significant changes in cortical excitability of the MI, as reflected by TMS-MEP stimulus-response curves or corticomotor maps for the tongue, masseter or FDI were found between baseline and post-injection for the LA (anovas: P > 0.22) or capsaicin (anovas: P > 0.16) sessions. These findings suggest that a transient loss or perturbation in periodontal afferent input to the brain from a single incisor is insufficient to cause changes in corticomotor excitability of the face MI, as measured by TMS in humans.
- Journal of oral rehabilitation.J Oral Rehabil.2010 Jan;37(1):39-47. doi: 10.1111/j.1365-2842.2009.02016.x. Epub 2009 Oct 30.
- The aim of the present study was to determine in humans whether local anaesthesia (LA) or nociceptive stimulation of the periodontal ligaments affects the excitability of the face primary motor cortex (MI) related to the tongue and jaw muscles, as measured by transcranial magnetic stimulation (TMS).
- PMID 19889035
- Transurethral resection of the prostate after intraprostatic injections of mepivacain epinephrine: a preliminary communication.
- Schelin S.Author information Urology Section, Department of Surgery, Kalmar County Hospital, Kalmar, Sweden. sonny.schelin@telia.comAbstractOBJECTIVE: Transurethral resection of the prostate (TURP) has been the gold standard for treatment of obstructive benign prostatic hyperplasia since the 1970s. Intraprostatic injections of mepivacain epinephrine (ME) (Carbocain-Adrenalin) before Core Therm (Prostalund feedback treatment) have been used to anaesthetize the gland and reduce the intraprostatic blood flow, thereby reducing discomfort, treatment time and energy consumption during transurethral microwave thermotherapy. As a result of this experience, use of this technique before TURP, to reduce perioperative bleeding and blood loss during TURP surgery, was investigated. This paper presents the author's first clinical experiences using the Schelin Catheter to add intraprostatic infiltrations of ME before TURP.
- Scandinavian journal of urology and nephrology.Scand J Urol Nephrol.2009;43(1):63-7. doi: 10.1080/00365590802465061.
- OBJECTIVE: Transurethral resection of the prostate (TURP) has been the gold standard for treatment of obstructive benign prostatic hyperplasia since the 1970s. Intraprostatic injections of mepivacain epinephrine (ME) (Carbocain-Adrenalin) before Core Therm (Prostalund feedback treatment) have been u
- PMID 19085323
- Effect of local anaesthetics on wound healing. An experimental study with special reference to carbocain. Acta Anaesth. Scandinav. 1957, 2, 87-99.
- Nilsson E, Wendeberg B.
- Acta anaesthesiologica Scandinavica.Acta Anaesthesiol Scand.2007 Sep;51(8):991-1003; discussion 1004.
- PMID 17697292
Japanese Journal
- 血液透析患者の糖尿病性神経障害に対する星状神経節ブロック（ＳＧＢ）療法の効果
- 日本透析医学会雑誌 27(10), 1309-1312, 1994
- NAID 130003874570
- 口腔内浸潤麻酔時転換性障害を思わせるような不快症状を呈した１例
- 日本歯科心身医学会雑誌 8(2), 129-134, 1993
- NAID 130004308152
- ケトプロフェン注射剤と各種局所麻酔剤との配合変化
- 病院薬学 12(4), 333-342, 1986-08-20
- NAID 110001798240
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