English Journal

Bone Marrow Mesenchymal Stromal Cells Induce Proliferative, Cytokinic and Molecular Changes During the T Cell Response: The Importance of the IL-10/CD210 Axis.

Najar M1, Raicevic G, Fayyad-Kazan H, De Bruyn C, Bron D, Toungouz M, Lagneaux L.
Stem cell reviews.Stem Cell Rev.2015 Jun;11(3):442-52. doi: 10.1007/s12015-014-9567-3.
BACKGROUND: Bone marrow mesenchymal stromal cells (BM-MSCs) display immunomodulatory features, representing a promising tool for cell-based therapies. However, the mechanisms used by MSCs to regulate T cell fate remain unclear.AIMS: We investigated the potential of BM-MSCs to modulate T cell activat
PMID 25326368

Development of asthmatic response upon bronchial allergen challenge is associated with dynamic changes of interleukin-10-producing and interleukin-10-responding CD4+ T cells.

Moniuszko M1, Grubczak K, Kowal K, Eljaszewicz A, Rusak M, Jeznach M, Jablonska E, Dabrowska M, Bodzenta-Lukaszyk A.
Inflammation.Inflammation.2014 Dec;37(6):1945-56. doi: 10.1007/s10753-014-9927-9.
The role of adaptive immune system in regulation of asthmatic responses remains elusive. Here, we performed a comprehensive time-course analysis of mutual relationships between development of asthmatic response following allergen challenge and changes in several CD4+ T cell subsets which we characte
PMID 24865466

Content of IL-10 and CD4+CD210+ cells in mice with adjuvant arthritis before and after treatment with cryopreserved placental cells.

Lutsenko ED1, Bondarovich NA, Gol'tsev AN.
Bulletin of experimental biology and medicine.Bull Exp Biol Med.2014 Sep;157(5):673-6. doi: 10.1007/s10517-014-2641-7. Epub 2014 Sep 27.
We analyzed the serum level of IL-10, blood content of CD4+СD210+ cells, and expression of IL-10 receptors in adjuvant arthritis before and after treatment with native and cryopreserved placental cells. In animals with experimental adjuvant arthritis, a negative correlation was found between the in
PMID 25257438