- 同
- T antigen, Thomsen-Friedenreich anti- gen
English Journal
- CD176 single-chain variable antibody fragment inhibits the adhesion of cancer cells to endothelial cells and hepatocytes.
- Liu J1,2, Yi B1,2, Zhang Z1,2, Cao Y3.
- Frontiers of medicine.Front Med.2016 Jun;10(2):204-11. doi: 10.1007/s11684-016-0443-1. Epub 2016 Apr 18.
- CD176 (Thomsen-Friedenreich antigen) is a tumor-associated carbohydrate epitope (glycotope) functionally involved in blood spread and liver metastasis of cancer cells by mediating the adhesion of cancer cells to endothelial cells and hepatocytes, respectively. CD176 could be a promising target for a
- PMID 27090911
- p53 determines prognostic significance of the carbohydrate stem cell marker TF1 (CD176) in ovarian cancer.
- Heublein S1,2, Page SK3, Mayr D4, Ditsch N3, Jeschke U3.
- Journal of cancer research and clinical oncology.J Cancer Res Clin Oncol.2016 Jun;142(6):1163-70. doi: 10.1007/s00432-016-2126-3. Epub 2016 Mar 2.
- INTRODUCTION: The oncofoetal Thomsen-Friedenreich (TF1, CD176) epitope is a carbohydrate cancer stem cell (CSC) antigen, and TF1-mediated cancer progression can be widely reversed by anti-TF1 antibodies. Particularly, CSC-like cells are regarded to be tumorigenic and chemoresistant. Aberrant p53 is
- PMID 26935926
- Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides.
- Rodriguez MC1,2, Yegorova S2, Pitteloud JP2, Chavaroche AE2, André S3, Ardá A4, Minond D2, Jiménez-Barbero J4,5, Gabius HJ3, Cudic M1.
- Biochemistry.Biochemistry.2015 Jul 28;54(29):4462-74. doi: 10.1021/acs.biochem.5b00555. Epub 2015 Jul 20.
- A shift to short-chain glycans is an observed change in mucin-type O-glycosylation in premalignant and malignant epithelia. Given the evidence that human galectin-3 can interact with mucins and also weakly with free tumor-associated Thomsen-Friedenreich (TF) antigen (CD176), the study of its interac
- PMID 26129647
Japanese Journal
- ドキュメント アスベスト禁止をめぐる世界の動き イギリス・アスベスト作業管理規則改正の再提案 : Consultative Document CD176, HSC, U.K., 2001.11.21
- 安全センター情報 (284), 30-37, 2002-03
- NAID 40020665938
Related Links
- Antibodies Antibodies applied were anti-CD44 mAb [G44-26 (mouse IgG2b); BD Biosciences, Franklin Lakes, NJ, USA], anti-CD133 mAb [ANC9C5 (mouse IgG); Ancell, Bayport, MN, USA], anti-CD176 mAb [NM-TF2 ...
- CD176 æƒ…å ±æº ãƒ¡ãƒ¼ã‚«ãƒ¼, ä¾¡æ ¼ ... Formalin-fixed, paraffin-embedded human colon adenocarcinoma stained with Thomsen-Friedenreich Antigen antibody using peroxidase-conjugate and DAB chromogen.
Related Pictures
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| 関連記事 | 「CD1」 |
「CD1」
- 同
- leucine-6, CD1A through E
種類
- CD1a, CD1b, CD1c, CD1d
発現組織
- 胸腺皮質、ランゲルハンス細胞、樹状細胞、B細胞(CD1c)、腸上皮、平滑筋、血管上皮(CD1d)
分子量
- 43-49
機能
- MHC class I-like molecule, associated with β2-microgloulin. Has specialized role in presentation of lipid antigens