WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

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Selective programming of CCR10(+) innate lymphoid cells in skin-draining lymph nodes for cutaneous homeostatic regulation.

Yang J1, Hu S1, Zhao L1, Kaplan DH2, Perdew GH3, Xiong N1.
Nature immunology.Nat Immunol.2016 Jan;17(1):48-56. doi: 10.1038/ni.3312. Epub 2015 Nov 2.
Innate lymphoid cells (ILCs) 'preferentially' localize into barrier tissues, where they function in tissue protection but can also contribute to inflammatory diseases. The mechanisms that regulate the establishment of ILCs in barrier tissues are poorly understood. Here we found that under steady-sta
PMID 26523865

TSLP Directly Interacts with Skin-Homing Th2 Cells Highly Expressing its Receptor to Enhance IL-4 Production in Atopic Dermatitis.

Tatsuno K1, Fujiyama T1, Yamaguchi H1, Waki M1, Tokura Y1.
The Journal of investigative dermatology.J Invest Dermatol.2015 Dec;135(12):3017-24. doi: 10.1038/jid.2015.318. Epub 2015 Aug 19.
Thymic stromal lymphopoietin (TSLP) is overtly expressed on skin lesions of atopic dermatitis (AD), and the initiative role of TSLP-activated DCs in AD has gained much attention in the past few years, while its actions on other immune cells such as T cells have been given less notice. We aimed to cl
PMID 26288354

CCR6(+) Th cell populations distinguish ACPA positive from ACPA negative rheumatoid arthritis.

Paulissen SM1, van Hamburg JP2, Davelaar N3, Vroman H4, Hazes JM5, de Jong PH6, Lubberts E7.
Arthritis research & therapy.Arthritis Res Ther.2015 Nov 30;17:344. doi: 10.1186/s13075-015-0800-5.
INTRODUCTION: Patients with rheumatoid arthritis (RA) can be separated into two major subpopulations based on the absence or presence of serum anti-citrullinated protein antibodies (ACPAs). The more severe disease course in ACPA(+) RA and differences in treatment outcome between these subpopulations
PMID 26617177