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English Journal
- [Cytokines in bone diseases. Genetic defects of PTH/PTHrP receptor in chondrodysplasia].
- Ogata N1.
- Clinical calcium.Clin Calcium.2010 Oct;20(10):1481-8. doi: CliCa101014811488.
- Parathyroid hormone-related protein (PTHrP) signaling plays important roles in regulating the differentiation of chondrocytes in endochondral bone development. PTHrP signaling functions as an inhibitory effect on chondrocyte hypertrophy which is a terminal stage of differentiation at a growth plate.
- PMID 20890029
- Absence of functional type 1 parathyroid hormone (PTH)/PTH-related protein receptors in humans is associated with abnormal breast development and tooth impaction.
- Wysolmerski JJ1, Cormier S, Philbrick WM, Dann P, Zhang JP, Roume J, Delezoide AL, Silve C.
- The Journal of clinical endocrinology and metabolism.J Clin Endocrinol Metab.2001 Apr;86(4):1788-94.
- Recent studies in transgenic mice have demonstrated that PTH-related protein (PTHrP), signaling through the type 1 PTH/PTHrP receptor (PTHR1), regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Recently, it has been s
- PMID 11297619
Japanese Journal
- Rat wild-type parathyroid hormone receptor (PTH-R) and mutant PTH-RP132L show the different intracellular localization in vitro
Related Links
- Blomstrand’s lethal chondrodysplasia Authors: Doctor Caroline Silve1 and Doctor Harald Jüppner2 Creation Date: January 2005 Scientific Editor: Doctor Valérie Cormier-Daire 1INSERM U. 426, Faculté de Médecine Xavier Bichat, 16 ...
- Blomstrand Lethal Chondrodysplasia is a neonatal osteosclerotic dysplasia characterized by advanced endochondral bone maturation, very short limbs ... What are the other Names for this Condition? (Also known as ...
★リンクテーブル★
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- 関
- deadly、fatal、fatally、lethally、mortal、vital
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- 関
- Skeletal dysplasia