ADP-ribosyl cyclase

ADPリボシルシクラーゼ

関

ADPR cyclase、cADPR hydrolase、cyclic ADP-ribose hydrolase

WordNet

1. the 1st letter of the Roman alphabet (同)a
2. the blood group whose red cells carry the A antigen (同)type_A, group A
3. in the Christian era; used before dates after the supposed year Christ was born; "in AD 200" (同)A.D., anno_Domini

PrepTutorEJDIC

1. answer / ampere

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• 1. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
• 2. Chapter 6A：ホルモンの作用機序 chapter 6a mechanisms of hormone action
• 3. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation
• 4. 心筋における興奮収縮連関 excitation contraction coupling in myocardium
• 5. 心不全および心筋梗塞における遺伝子療法および細胞療法 genetic and cellular therapy in heart failure and myocardial infarction

English Journal

• Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate.

• Ikeda T, Takasawa S, Noguchi N, Nata K, Yamauchi A, Takahashi I, Yoshikawa T, Sugawara A, Yonekura H, Okamoto H.SourceDepartment of Biochemistry, Kanazawa Medical University School of Medicine, 1-1 Daigaku, Uchinada, Kahoku-gun, Ishikawa, 920-0293, Japan, tikeda@kanazawa-med.ac.jp.
• Molecular and cellular biochemistry.Mol Cell Biochem.2012 Mar 16. [Epub ahead of print]
• Cyclic ADP-ribose (cADPR), a metabolite of NAD(+), is known to function as a second messenger for intracellular Ca(2+) mobilization in various vertebrate and invertebrate tissues. In this study, we isolated two Xenopus laevis cDNAs (frog cd38 and cd157 cDNAs) homologous to the one encoding the huma
• PMID 22422046

• The role of CD38 in Fc gamma receptor (FcγR)-mediated phagocytosis in murine macrophages.

• Kang J, Park KH, Kim JJ, Jo EK, Han MK, Kim UH.SourceChonbuk National University Medical School, Korea, Republic of;
• The Journal of biological chemistry.J Biol Chem.2012 Mar 6. [Epub ahead of print]
• Phagocytosis is a crucial event in the immune system that allows cells to engulf and eliminate pathogens. This is mediated through the action of immunoglobulin (IgG)- opsonized microbes acting on Fcγ receptors (FcγR) on macrophages, which results in sustained levels of intracellular Ca2+ through t
• PMID 22396532

Japanese Journal

• 社会性記憶と自閉症：末梢オキシトシン投与による症状改善とCD38の一塩基置換

• 東田 陽博
• Drug Delivery System 28(4), 310-317, 2013
• オキシトシンは脳内に放出され、扁桃体をはじめとする「社会脳」領域を介して社会性行動、特に信頼を基礎とするあらゆる人間相互間活動に影響を与える。オキシトシン遺伝子や受容体、オキシトシンの脳内分泌を制御するCD38などがそれらの機能を司る。オキシトシンの鼻腔単回投与により健常人、自閉症スペクトラム障害者ともに、目を見るなどの対人関係行動の改善や促進があり、連続投与により、社会性障害症状の改善が報告され …
• NAID 130003384381

• Social memory, amnesia, and autism: Brain oxytocin secretion is regulated by NAD + metabolites and single nucleotide polymorphisms of CD38

• Higashida Haruhiro,Yokoyama Shigeru,Huang Jian-Jun,Liu Li,Ma Wen-Jie,Akther Shirin,Higashida Chiharu,Kikuchi Mitsuru,Minabe Yoshio,Munesue Toshio
• Neurochemistry International 61(6), 828-838, 2012-11
• … Previously, we demonstrated that CD38, a transmembrane protein with ADP-ribosyl cyclase activity, plays a critical role in mouse social behavior by regulating the release of oxytocin (OXT), which is essential for mutual recognition. …
• NAID 120004966608

• CD38 and its role in oxytocin secretion and social behavior

• Higashida Haruhiro,Yokoyama Shigeru,Kikuchi Mitsuru,Munesue Toshio
• Hormones and Behavior 61(3), 351-358, 2012-03
• … Here, we review the functional roles of cyclic ADP-ribose and CD38, a transmembrane protein with ADP-ribosyl cyclase activity, in mouse social behavior via the regulation of oxytocin (OXT) release, an essential component of social cognition. …
• NAID 120003959468

Related Links

• Effect of estrogen upon cyclic ADP ribose metabolism: β ...

In our previous study we observed that all-trans-retinoic acid stimulates cADPR synthesis by ADP ribose cyclase (ADPR cyclase) in cultured epithelial cells. We have now investigated whether cADPR may play ...

• DrugBank: ADP-ribosyl cyclase 2

General Function Involved in NAD+ nucleosidase activity Specific Function Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth Pathways Not ...

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★リンクテーブル★

リンク元	「cADPR hydrolase」「ADPリボシルシクラーゼ」「cyclic ADP-ribose hydrolase」「ADPR cyclase」「ADP-リボシルシクラーゼ」
関連記事	「ADP」「A」「cyclase」「AD」

「cADPR hydrolase」

　　[★]

cADPR加水分解酵素、cADPRヒドロラーゼ、サイクリックADPリボースヒドロラーゼ

関

ADP-ribosyl cyclase、ADPR cyclase、cyclic ADP-ribose hydrolase

「ADPリボシルシクラーゼ」

　　[★]

英

ADP-ribosyl cyclase、ADPR cyclase

関

ADP-リボシルシクラーゼ、サイクリックADPリボースヒドロラーゼ

「cyclic ADP-ribose hydrolase」

　　[★]

サイクリックADPリボースヒドロラーゼ

関

ADP-ribosyl cyclase、ADPR cyclase、cADPR hydrolase

「ADPR cyclase」

　　[★]

ADPリボシルシクラーゼ

関

ADP-ribosyl cyclase、cADPR hydrolase、cyclic ADP-ribose hydrolase

「ADP-リボシルシクラーゼ」

　　[★]

英

ADP-ribosyl cyclase

関

ADPリボシルシクラーゼ

「ADP」

　　[★]

• アデノシン二リン酸 adenosine diphosphate adenosine 5'-diphosphate
• 5-aminolevulinic acid dehydratase porphyria
• 母指内転筋 adductor pollicis

「A」

　　[★]

• アデニン adenine
• アデノシン adenosine
• アラニン alanine

　 　 　

「cyclase」

　　[★]

シクラーゼ、サイクレース、環化酵素

「AD」

　　[★]

• atopic dermatitis
• advance directives