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1. ミトコンドリアミオパシー：臨床的特徴および診断 mitochondrial myopathies clinical features and diagnosis
2. 敗血症の病態生理 pathophysiology of sepsis
3. Chapter 5A：遠位尿細管と接合部分 chapter 5a distal tubule and connecting segment
4. 補体経路 complement pathways
5. B群レンサ球菌：病原性因子および発症機序 group b streptococcus virulence factors and pathogenic mechanisms

English Journal

Recombinant Chicken Interferon-α Inhibits H9N2 Avian Influenza Virus Replication In Vivo by Oral Administration.

Meng S, Yang L, Xu C, Qin Z, Xu H, Wang Y, Sun L, Liu W.Source1 CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology , Chinese Academy of Sciences, Beijing, People's Republic of China .
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.J Interferon Cytokine Res.2011 Jul;31(7):533-8. Epub 2011 Feb 16.
Chicken interferon-alpha (ChIFN-α) has been demonstrated to be an important cytokine in antiviral immunity. However, the preventive or therapeutic effect of ChIFN-α as an oral antiviral agent on avian influenza virus (AIV) infection has not been fully clarified in chickens systemically. In the pre
PMID 21323426

Use of modelling & simulation techniques to support decision making on the progression of PF-04878691, a TLR7 agonist being developed for Hepatitis C.

Jones HM, Chan PL, van der Graaf PH, Webster R.SourcePfizer Worldwide R&D, Department of Pharmacokinetics, Dynamics and Metabolism, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK. Pfizer Worldwide R&D, Global Clinical Pharmacology, Pharmacometrics, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK.
British journal of clinical pharmacology.Br J Clin Pharmacol.2011 Jun 21. doi: 10.1111/j.1365-2125.2011.04047.x. [Epub ahead of print]
What is already known about the subject; While several clinical studies have been published using TLR7 agonists, there is no information on the quantitative link between 2',5'-oligoadenylate synthetase (OAS) and antiviral efficacy (viral load). What this paper adds: This study provides the only quan
PMID 21689140

Differentiating between bacterial and viral infection by measuring both C-reactive protein and 2'-5'-oligoadenylate synthetase as inflammatory markers

SASAKI Kazuya,FUJITA Ichiro,HAMASAKI Yuhei,MIYAZAKI Sumio
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 8(1), 76-80, 2002-03-01
NAID 10013892334

Crystal Structure of Asparagine Synthetase Reveals a Close Evolutionary Relationship to Class II Aminoacyl-tRNA Synthetase (MOLECULAR BIOFUNCTION-Functional Molecular Conversion)

Nakatsu Toru,Kato Hiroaki,Oda Jun'ichi
ICR annual report 4, 44-45, 1998-03
… coli asparagine synthetase has been determined by X-ray diffraction analysis at 2.5 A resolution. … The overall structure of the enzyme is remarkably similar to that of the catalytic domain of yeast aspartyl-tRNA synthetase despite low sequence similarity. …
NAID 120000885601