トリメチルアンモニウム

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1. 抗利尿ホルモン不適合分泌（SIADH）症候群の病態生理および病因 pathophysiology and etiology of the syndrome of inappropriate antidiuretic hormone secretion siadh
2. 子宮外妊娠：メトトレキサート療法 ectopic pregnancy methotrexate therapy
3. 再発性または難治性多発性骨髄腫の治療 treatment of relapsed or refractory multiple myeloma
4. 免疫グロブリン軽鎖（AL）アミロイドーシスおよび軽鎖重鎖沈着症の予後および治療 prognosis and treatment of immunoglobulin light chain al amyloidosis and light and heavy chain deposition diseases
5. 多発性骨髄腫患者のマネージメントの概要 overview of the management of multiple myeloma

Central muscarinic cholinergic activation alters interaction between splenic dendritic cell and CD4+CD25- T cells in experimental colitis.

Munyaka P1, Rabbi MF1, Pavlov VA2, Tracey KJ2, Khafipour E3, Ghia JE4.
PloS one.PLoS One.2014 Oct 8;9(10):e109272. doi: 10.1371/journal.pone.0109272. eCollection 2014.
BACKGROUND: The cholinergic anti-inflammatory pathway (CAP) is based on vagus nerve (VN) activity that regulates macrophage and dendritic cell responses in the spleen through alpha-7 nicotinic acetylcholine receptor (a7nAChR) signaling. Inflammatory bowel disease (IBD) patients present dysautonomia
PMID 25295619

Activation of central muscarinic receptor type 1 prevents development of endotoxin tolerance in rat liver.

Eftekhari G1, Hajiasgharzadeh K1, Ahmadi-Soleimani SM1, Dehpour AR2, Semnanian S1, Mani AR3.
European journal of pharmacology.Eur J Pharmacol.2014 Oct 5;740:436-41. doi: 10.1016/j.ejphar.2014.06.050. Epub 2014 Jul 4.
Endotoxin tolerance is a mechanism in which cells receiving low doses of endotoxin, enter a transient phase with less inflammatory response to the next endotoxin challenges. Central nervous system is known to modulate systemic inflammation through activation of the cholinergic system; however, the r
PMID 25008070

Regulation of persistent activity in hippocampal mossy cells by inhibitory synaptic potentials.

Anderson RW1, Strowbridge BW.
Learning & memory (Cold Spring Harbor, N.Y.).Learn Mem.2014 Apr 15;21(5):263-71. doi: 10.1101/lm.033829.113.
The hippocampal formation receives strong cholinergic input from the septal/diagonal band complex. Although the functional effects of cholinergic activation have been extensively studied in pyramidal neurons within the hippocampus and entorhinal cortex, less is known about the role of cholinergic re
PMID 24737918