関: メタロプロテアーゼ組織阻害物質、組織メタロプロテアーゼ

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1. 胸部大動脈瘤解離の疫学、危険因子、発症機序、自然経過epidemiology risk factors pathogenesis and natural history of thoracic aortic aneurysm and dissection [show details]
… and B) levels; local overexpression of tissue inhibitor of matrix metalloproteinases, produced by retrovirus-infected smooth muscle cells, can prevent aneurysmal degeneration and rupture . Familial TAA …
2. 慢性関節リウマチにおける滑膜異常synovial pathology in rheumatoid arthritis [show details]
…of active metalloproteinases in synovial tissue are associated with erosive disease . Gelatinases have also been identified in RA synovial tissues. The tissue inhibitors of metalloproteinases are naturally …
3. 変形性関節症のマネージメントへの研究的アプローチinvestigational approaches to the management of osteoarthritis [show details]
…focused on inhibiting nerve growth factor. There is evidence supporting the role of nerve growth factor in the development of sensory neurons such as nociceptors, which are involved in sensing tissue damage… IL-1 is capable of inducing expression of matrix metalloproteinases (MMPs) and other catabolic genes,…
4. 慢性閉塞性肺疾患（COPD）：危険因子およびリスク低減chronic obstructive pulmonary disease risk factors and risk reduction [show details]
… Matrix metalloproteinases (MMPs) are a family of zinc-dependent enzymes that degrade extracellular matrix proteins. The activity of MMPs is regulated by tissue inhibitors of metalloproteinase (TIMPs) …
5. 肝線維症の非侵襲的評価：血清学的検査および画像診断noninvasive assessment of hepatic fibrosis overview of serologic and radiographic tests [show details]
…surface mechanisms for functional activity. They are in turn inhibited by tissue inhibitors of metalloproteinases (TIMPs). Matrix metalloproteinases – The observation that MMPs are expressed in liver injury …