関: 抗トポイソメラーゼI抗体

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 抗核抗体染色パターンおよび関連自己抗体の臨床的意義clinical significance of antinuclear antibody staining patterns and associated autoantibodies [show details]
…individuals. In patients with diffuse SSc, anti-Scl70 antibodies are associated with the presence of interstitial pulmonary fibrosis . Anti-Ku antibodies are rare, with an estimated prevalence of 0 …
2. 抗核抗体の測定および臨床的意義measurement and clinical significance of antinuclear antibodies [show details]
… immunofluorescence if anti-Ro60 is the only autoantibody present in serum . Similarly, antibodies directed against ribosomal P antigens may be difficult to detect using the HEp-2 cell substrate . Anti-ribosomal… antigens used in solid phase assays may include all or some of the following: Ro, La, Sm, U1 RNP, Scl-70, PM-Scl, Jo-1, centromere, histone, ribosomal P, and DNA. Diluted human serum is incubated with the …
3. 若年性特発性関節炎：疫学と免疫病態学juvenile idiopathic arthritis epidemiology and immunopathogenesis [show details]
… these antibodies are present in other rheumatic diseases . Anticollagen , antiretinal , and anti-T cell antibodies have been described,… Antibodies to many antigens typical for other rheumatic diseases (eg, the extractable nuclear protein, centromere proteins, topoisomerase [Scl-70],…
4. 成人における全身性硬化症（強皮症）の診断および鑑別診断diagnosis and differential diagnosis of systemic sclerosis scleroderma in adults [show details]
… the diagnosis if positive: Antinuclear antibody (ANA) Antitopoisomerase I (anti-Scl-70) antibody; Anticentromere antibody (ACA) Anti-RNA polymerase III antibody; Additional studies focusing on specific …
5. 強皮症の概要および分類overview and classification of scleroderma disorders [show details]
…percent), and in healthy persons (7 percent). Unlike testing for antibodies to topoisomerase I (anti-Scl-70), a commercial assay for anti-topoisomerase II is not available. It has been observed that other …