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1. 骨転移の機序mechanisms of bone metastases [show details]
… Bone is the third most frequent site of tumor metastasis; it is estimated that 280,000 patients in the United States are living with bone metastases . Bone is the preferred site for breast and prostate …
2. 糖尿病における骨疾患bone disease in diabetes mellitus [show details]
… The effects of diabetes on bone are complex. While most studies agree that fracture risk is increased in diabetes, bone mineral density (BMD) may not reflect bone fragility, particularly in type 2 diabetes …
3. 骨代謝の生理学および生化学的マーカーbone physiology and biochemical markers of bone turnover [show details]
… (tartrate-resistant acid phosphatase, TRAP). The osteoclasts attach to the bone surface and secrete acid and hydrolytic enzymes that resorb bone, releasing bone minerals and fragments of collagen. Some of the collagen is …
4. 抗てんかん剤と骨疾患antiepileptic drugs and bone disease [show details]
… AEDs are associated with adverse effects on bone health. Persons with epilepsy treated with AEDs have increased rates of bone loss and abnormalities in bone and mineral metabolism . These adverse effects …
5. 骨サルコイドーシスsarcoidosis of bone [show details]
…specifically involving bone is uncertain; it has been postulated that antigenic particles are spread hematogenously or through the lymphatics, creating granulomas within the bone, bone marrow, and other organs …