WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

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Selective and potent inhibitory effect of docosahexaenoic acid (DHA) on U46619-induced contraction in rat aorta

Sato Kyosuke,Chino Daisuke,Kobayashi Tomoya,Obara Keisuke,Miyauchi Seiji,Tanaka Yoshio
Journal of Smooth Muscle Research 49(0), 63-77, 2013
… DHA also significantly diminished PGF2α-induced contraction but did not show any appreciable inhibitory effects on the contractions to both phenylephrine (PE) and high-KCl. … Similarly, EPA exhibited significant inhibitory effects against the contractions induced by both U46619 and PGF2α without substantially affecting either PE- or high-KCl-induced contractions. … However, both DHA and EPA generated more potent inhibitions against contractions induced by U46619 than those by PGF2α. …
NAID 130003382356

玉置淳
東京女子医科大学雑誌 82(2), 92-96, 2012-04-25
… やされているのが現状である.そこで重症難治性喘息の管理・克服は今後の重要な課題であり,そのための新しい治療手段の1つとして様々な生物学的製剤が開発されている.これらはIgE抗体やIL-5抗体,あるいはTNFαを標的とした抗体や可溶性受容体であり,いずれも好酸球性あるいは好中球性気道炎症を分子レベルで治療しようというコンセプトの薬剤である.最近の臨床試験によれば,これらの薬剤は重症難治性喘息の呼吸 …
NAID 110009004311

杉山和久,東出朋巳,大久保真司,新田耕治,武田久,奥田徹彦,桜井真由美,長田敦,斎藤代志明,高橋真美,前田有,辻屋壮介,室谷英治,若林祐佳,高延琳,中谷雄介,馬渡嘉郎,川口一朗,川口千晶,岡村均,可児一孝,樋田一徳,岩瀬愛子,川瀬和秀,兼子博章,福平由佳子
日本眼科學会雜誌 116(3), 233-268, 2012-03-10
… We evaluated the relationship between the genetic polymorphisms of the adrenergic receptor (ADR) and the diurnal IOP in untreated NTG patients. … For Del 301-303 in α2B-ADR, De1322-325 in α2C-ADR, and S 49G (A/G) in βl-ADR, the major homozygotes and minor carriers had parallel diurnal IOP curves, but significantly different diurnal IOP levels. …
NAID 10030249484