関: TNFR-I、TNFR1、tumor necrosis factor receptor

WordNet

write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
(biology) the taxonomic group whose characteristics are used to define the next higher taxon
a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
all of the tokens of the same symbol; "the word `element contains five different types of character"
printed characters; "small type is hard to read"
identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
the 9th letter of the Roman alphabet (同)i
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
『私は』私が
iodineの化学記号
=sense organ / 受信装置

UpToDate Contents

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1. 腫瘍壊死因子受容体-1関連周期性発熱症候群（TRAPS） tumor necrosis factor receptor 1 associated periodic syndrome traps
2. 体液性免疫応答 the humoral immune response
3. 周期性発熱症候群およびその他の自己炎症性疾患：概要 periodic fever syndromes and other autoinflammatory diseases an overview
4. 1型糖尿病の予防 prevention of type 1 diabetes mellitus
5. 移植免疫 transplantation immunobiology

English Journal

Inflammatory cytokine receptor blockade in a rodent model of mild traumatic brain injury.

Perez-Polo JR1, Rea HC1, Johnson KM1, Parsley MA1, Unabia GC1, Xu GY1, Prough D1, DeWitt DS1, Paulucci-Holthauzen AA1, Werrbach-Perez K1, Hulsebosch CE1.
Journal of neuroscience research.J Neurosci Res.2016 Jan;94(1):27-38. doi: 10.1002/jnr.23617. Epub 2015 Jul 14.
In rodent models of traumatic brain injury (TBI), both Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNFα) levels increase early after injury to return later to basal levels. We have developed and characterized a rat mild fluid percussion model of TBI (mLFP injury) that results in righting
PMID 26172557

P2X7 Receptor Expression in Peripheral Blood Monocytes Is Correlated With Plasma C-Reactive Protein and Cytokine Levels in Patients With Type 2 Diabetes Mellitus: a Preliminary Report.

Wu H1, Nie Y2, Xiong H1, Liu S1, Li G1, Huang A3, Guo L1, Wang S1, Xue Y1, Wu B1, Peng L1, Song M1, Li G1, Liang S4.
Inflammation.Inflammation.2015 Dec;38(6):2076-81. doi: 10.1007/s10753-015-0189-y.
Chronic inflammation plays a major role in development of type 2 diabetes mellitus (T2DM). C-reactive protein (CRP) and inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin 1β (IL-1β) are directly involved in the occurrence of insulin resistance. Increased extracellular
PMID 26021292

Protective effects of the angiotensin type 1 receptor antagonist losartan in infection-induced and arthritis-associated alveolar bone loss.

Queiroz-Junior CM1,2, Silveira KD2, de Oliveira CR1,2, Moura AP1, Madeira MF1,3, Soriani FM4, Ferreira AJ5, Fukada SY6, Teixeira MM2, Souza DG3, da Silva TA1.
Journal of periodontal research.J Periodontal Res.2015 Dec;50(6):814-23. doi: 10.1111/jre.12269. Epub 2015 Mar 5.
BACKGROUND AND OBJECTIVE: The angiotensin type 1 (AT1) receptor has been implicated in the pathogenesis of inflammatory bone disorders. This study aimed to investigate the effect of an AT1 receptor antagonist in infection-induced and arthritis-associated alveolar bone loss in mice.MATERIAL AND METHO
PMID 25753377

Japanese Journal

Irciniastatin A Induces Potent and Sustained Activation of Extracellular Signal-Regulated Kinase and Thereby Promotes Ectodomain Shedding of Tumor Necrosis Factor Receptor 1 in Human Lung Carcinoma A549 Cells

Quach Hue Tu,Hirano Seiya,Fukuhara Sayuri [他],Watanabe Tsubasa,Kanoh Naoki,Iwabuchi Yoshiharu,Usui Takeo,Kataoka Takao
Biological and Pharmaceutical Bulletin 38(6), 941-946, 2015
… Irciniastatin A is a pederin-type marine product that potently inhibits translation. … We have recently shown that irciniastatin A induces ectodomain shedding of tumor necrosis factor (TNF) receptor 1 with slower kinetics than other translation inhibitors. …
NAID 130005072659

Macrophage-mediated glucolipotoxicity via myeloid-related protein 8/toll-like receptor 4 signaling in diabetic nephropathy.

Kuwabara Takashige,Mori Kiyoshi,Mukoyama Masashi,Kasahara Masato,Yokoi Hideki,Nakao Kazuwa
Clinical and experimental nephrology 18(4), 584-592, 2014-08
… Dyslipidemia is an independent risk factor for the development and progression of diabetic nephropathy (DN). … We focus especially upon toll-like receptor 4 (TLR4) and one of its endogenous ligands, myeloid-related protein 8 (MRP8 or S100A8), since we have found that their mRNA levels are commonly increased in glomeruli of type 1 (streptozotocin [STZ]-induced) and type 2 (A-ZIP/F-1 lipoatrophic) diabetic mice. …
NAID 120005474441

Increased Interleukin-18 in the Gingival Tissues Evokes Chronic Periodontitis after Bacterial Infection

Yoshinaka Kotaro,Shoji Noriaki,Nishioka Takashi,Sugawara Yumiko,Hoshino Tomoaki,Sugawara Shunji,Sasano Takashi
The Tohoku Journal of Experimental Medicine 232(3), 215-222, 2014
… IL-18Tg and wild-type mice were inoculated intraorally with Porphyromonas (P.) gingivalis, which has been implicated in the etiology of chronic periodontitis. … Periodontal bone loss was evoked in IL-18Tg mice, but not in wild-type mice. … Interestingly, levels of bone-resorptive cytokines, including IL-1α, IL-1β, tumor necrosis factor-α, and IL-6, were unchanged in the gingival tissues of IL-18Tg mice infected with P. …
NAID 130004822404