transgenic mouse model

• 遺伝子導入マウスモデル、トランスジェニックマウスモデル、形質転換マウスモデル

WordNet

1. display (clothes) as a mannequin; "model the latest fashion"
2. the act of representing something (usually on a smaller scale) (同)modelling, modeling
3. representation of something (sometimes on a smaller scale) (同)simulation
4. a representative form or pattern; "I profited from his example" (同)example
5. a person who poses for a photographer or painter or sculptor; "the president didnt have time to be a model so the artist worked from photos" (同)poser
6. someone worthy of imitation; "every child needs a role model" (同)role model
7. a hypothetical description of a complex entity or process; "the computer program was based on a model of the circulatory and respiratory systems" (同)theoretical account, framework
8. a type of product; "his car was an old model"
9. construct a model of; "model an airplane" (同)mock up
10. form in clay, wax, etc; "model a head with clay" (同)mold, mould
11. plan or create according to a model or models (同)pattern
12. assume a posture as for artistic purposes; "We dont know the woman who posed for Leonardo so often" (同)pose, sit, posture
13. create a representation or model of; "The pilots are trained in conditions simulating high-altitude flights" (同)simulate
14. manipulate the mouse of a computer
15. a hand-operated electronic device that controls the coordinates of a cursor on your computer screen as you move it around on a pad; on the bottom of the device is a ball that rolls on the surface of the pad; "a mouse takes much more room than a trackball" (同)computer mouse
16. any of numerous small rodents typically resembling diminutive rats having pointed snouts and small ears on elongated bodies with slender usually hairless tails
17. person who is quiet or timid
18. a particular functioning condition or arrangement; "switched from keyboard to voice mode"
19. the most frequent value of a random variable (同)modal value
20. any of various fixed orders of the various diatonic notes within an octave (同)musical mode
21. relating to a recently developed fashion or style; "their offices are in a modern skyscraper"; "tables in modernistic designs"; (同)modern, modernistic
22. a British teenager or young adult in the 1960s; noted for their clothes consciousness and opposition to the rockers

PrepTutorEJDIC

1. (通名縮小した)(…の)『模型』,ひな型《+『of』+『名』》 / 《単数形で》(…の)『模範』,手本《+『of』+(『for』)+『名』》 / (美術家・作家などの)モデル,ファッションモデル / (自動車・服装などの)型,式《+『of』+『名』》 / 《英》《単数形で》(…と)そっくりな人(物),(…の)生き写し《+『of』+『名』》 / 『模型の』,見本の / 『日範的な』,申し分のない / (ある材料で)…‘の'模型を作る,‘を'型どる《+『名』+『in』+『名』〈材料〉》 / (手本・型に合わせて)…‘を'作る《+『名』+『after』(『on, upon』)+『名』(a person's do『ing』)》 / 〈洋装・髪型などの〉‘の'モデルをする / (…で)(原型)を作る《+『in』+『名』》 / (ファッションショーなどで)モデルをする
2. 『ハツカネズミ』(英米の家によく出没する小型のネズミ;ほが国の家に出没する大型のネズミはrat) / 《話》臆病者,内気な人 / 《猫が》ネズミを捜す(捕らえる) / 《人が》(…を)あさり歩く《+『about』+『名』》
3. 〈C〉(…の)『方法』,やり方,流儀《+『of』+『名』(do『ing』)》 / 〈U〉〈C〉(服装などの)『流行』,モード / 〈C〉(動詞の)法,叙法(mood) / 音階(scale)
4. モッズふうな(服装・音楽などについて伝統にとらわれない考え方の一つ)[modernの短縮形]

UpToDate Contents

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• 1. 遺伝学およびゲノミクスのためのツール：研究用に育種された遺伝子改変マウス tools for genetics and genomics specially bred and genetically engineered mice
• 2. 筋萎縮性側索硬化症の病態修飾療法 disease modifying treatment of amyotrophic lateral sclerosis
• 3. 筋萎縮性側索硬化症の疫学および病因 epidemiology and pathogenesis of amyotrophic lateral sclerosis
• 4. 内皮：プライマー the endothelium a primer
• 5. 慢性骨髄性白血病の細胞生物学および分子生物学 cellular and molecular biology of chronic myeloid leukemia

English Journal

• Transgenic Expression of Osteoactivin/gpnmb Enhances Bone Formation In Vivo and Osteoprogenitor Differentiation Ex Vivo.

• Frara N1, Abdelmagid SM2, Sondag GR3,4, Moussa FM3,4, Yingling VR5, Owen TA6, Popoff SN1, Barbe MF1, Safadi FF3,4.
• Journal of cellular physiology.J Cell Physiol.2016 Jan;231(1):72-83. doi: 10.1002/jcp.25020.
• Initial identification of osteoactivin (OA)/glycoprotein non-melanoma clone B (gpnmb) was demonstrated in an osteopetrotic rat model, where OA expression was increased threefold in mutant bones, compared to normal. OA mRNA and protein expression increase during active bone regeneration post-fracture
• PMID 25899717

• Lack of support for bexarotene as a treatment for Alzheimer's disease.

• O'Hare E1, Jeggo R2, Kim EM3, Barbour B4, Walczak JS5, Palmer P6, Lyons T7, Page D8, Hanna D9, Meara JR10, Spanswick D11, Guo JP12, McGeer EG12, McGeer PL13, Hobson P14.
• Neuropharmacology.Neuropharmacology.2016 Jan;100:124-30. doi: 10.1016/j.neuropharm.2015.04.020. Epub 2015 May 27.
• Bexarotene has been reported to reduce brain amyloid-β (Aβ) levels and to improve cognitive function in transgenic mouse models of Alzheimer's disease (AD). Four groups failed to fully replicate the primary results but the original authors claimed overall support for the general conclusions. Becau
• PMID 26025659

• Color-Coded Imaging of Breast Cancer Metastatic Niche Formation in Nude Mice.

• Suetsugu A1,2,3, Momiyama M2,3, Hiroshima Y2,3, Shimizu M1, Saji S1, Moriwaki H1, Bouvet M3, Hoffman RM2,3.
• Journal of cellular biochemistry.J Cell Biochem.2015 Dec;116(12):2730-4. doi: 10.1002/jcb.25227.
• We report here a color-coded imaging model in which metastatic niches in the lung and liver of breast cancer can be identified. The transgenic green fluorescent protein (GFP)-expressing nude mouse was used as the host. The GFP nude mouse expresses GFP in all organs. However, GFP expression is dim in
• PMID 25981355

Japanese Journal

• Expression of Microsomal Prostaglandin E Synthase-1 in the Spinal Cord in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

• Miyagishi Hiroko,Kosuge Yasuhiro,Ishige Kumiko [他]
• Journal of pharmacological sciences 118(2), 225-236, 2012-02
• NAID 40019161605

• A Novel Diabetes Mellitus Mouse Model, MAFA-Deficient and Beta Cell-Specific MAFK-Overexpressing Hybrid Transgenic Mice, Developed Severe Diabetic Nephropathy and Improved with TCV-116 (Candesartan Cilexetil) Treatment

• FUJITA Akiko,YOH Keigyou,SHIMOHATA Homare [他]
• Experimental animals 61(1), 49-57, 2012-01
• NAID 40019144961

Related Links

• Transgenic mouse : transgenesis history, transgenesis ...

Transgenic Mouse Since the first gene transfers into mice were successfully executed in 1980, transgenic mice have allowed researchers to observe experimentally the roles of genes in development, physiology and disease. ...

• モデルマウス｜株式会社トランスジェニック

株式会社トランスジェニックの小胞体ストレス可視化マウス、酸化ストレス可視化マウス、夜型モデルマウス（Clock変異マウス）。ERAI遺伝子で小胞体ストレスを可視化する小胞体ストレス可視化マウス（ERAI-Lucマウス）。OKD遺伝子で ...

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★リンクテーブル★

リンク元	「形質転換マウスモデル」「遺伝子導入マウスモデル」「トランスジェニックマウスモデル」
関連記事	「transgenic」「mode」「model」「mouse model」

「形質転換マウスモデル」

　　[★]

英

transgenic mouse model

関

遺伝子導入マウスモデル、トランスジェニックマウスモデル

「遺伝子導入マウスモデル」

　　[★]

英

transgenic mouse model

関

トランスジェニックマウスモデル、形質転換マウスモデル

「トランスジェニックマウスモデル」

　　[★]

英

transgenic mouse model

関

遺伝子導入マウスモデル、形質転換マウスモデル

「transgenic」

　　[★]

• adj.

• 遺伝子導入の、形質転換の、遺伝子組換えの、トランスジェニック

関

congenic、gene transfer、genetic transformation、Tg、transform、transformation、transforming、transgenesis、transgenically

「mode」

　　[★]

• n.

• モード、型、機序、方法

関

fashion、form、manner、means、mechanism、method、pattern、procedure、process、type、typed、way

　 　 　 　

「model」

　　[★]

• n.

• モデル、模型

　 　 　 　 　 　 　 　 　 　 　 　 　 　

「mouse model」

　　[★]

• マウスモデル

関

murine model