出典: meddic

corticosteroid-binding globulin

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/08/27 17:14:37」(JST)

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  • Corticosteroid-binding globulin cleavage may be pathogen-dependent in bloodstream infection.
  • Nenke MA1, Lewis JG2, Rankin W3, Shaw D4, Torpy DJ5.
  • Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2017 Jan;464:176-181. doi: 10.1016/j.cca.2016.11.033. Epub 2016 Nov 22.
  • OBJECTIVE: The process of enzymatic cleavage of high- to low-affinity corticosteroid-binding globulin (haCBG to laCBG) by neutrophil elastase leads to local tissue release of cortisol. Recently Pseudomonas aeruginosa was shown to instigate CBG cleavage with release of free cortisol in vitro. Hence,
  • PMID 27887960
  • Emerging Role of Corticosteroid-Binding Globulin in Glucocorticoid-Driven Metabolic Disorders.
  • Moisan MP1, Castanon N1.
  • Frontiers in endocrinology.Front Endocrinol (Lausanne).2016 Dec 19;7:160. doi: 10.3389/fendo.2016.00160. eCollection 2016.
  • Glucocorticoid hormones (GCs) are critical for survival since they ensure the energy supply necessary to the body in an ever challenging environment. GCs are known to act on appetite, glucose metabolism, fatty acid metabolism, and storage. However, to be beneficial to the body, GC levels should be m
  • PMID 28066325
  • Enhanced Activity of Topical Hydrocortisone by Competitive Binding of Corticosteroid-Binding Globulin.
  • Bodor ET1, Wu WM2, Chandran VR3, Bodor N2.
  • Journal of pharmaceutical sciences.J Pharm Sci.2016 Sep;105(9):2873-8. doi: 10.1016/j.xphs.2016.03.028. Epub 2016 May 11.
  • Atopic dermatitis of sensitive areas such as the face, particularly in children, is a difficult disease to treat as the standard therapeutic, topical steroids, is contraindicated for this application in children. Hydrocortisone (HC) can be used in these instances because it has been shown to be safe
  • PMID 27179671


  • Acute hepatotoxicity of DDT : Effect on glucocorticoid receptors and serum transcortin
  • The Influence of Transcortin on Adrenocorticotropin-Stimulated Corticosterone Production in Monolayer Cultured Rat Adrenal Cells.
  • Comparative study of primates' transcortin: Immunoreactivity and steroid-binding activity.


Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is an alpha- globulin. Contents. 1 Function; 2 Binding; 3 Synthesis; 4 Clinical significance; 5 See ...



先読みcorticosteroid-binding globulin

corticosteroid-binding globulin」


CBG/ transcortin