WordNet

any of the salts of hydrobromic acid; formerly used as a sedative but now generally replaced by safer drugs

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〈U〉臭化物(鎮静剤・睡眠剤として用いる) / 〈C〉《話》陳腐なことば

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/10/25 18:39:45」(JST)

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Timepidium bromide (INN) is an anticholinergic. The quaternary nitrogen prevents it from crossing the blood brain barrier, so it is peripherally acting with no central side effects.

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1. 成人における感冒：治療および予防 the common cold in adults treatment and prevention
2. 代謝性アシドーシス以外の状況における血清アニオンギャップ serum anion gap in conditions other than metabolic acidosis
3. 12歳未満の小児における慢性喘息：発作治療剤 chronic asthma in children younger than 12 years quick relief agents
4. 小児における喘息の急性増悪：外来管理 acute asthma exacerbations in children outpatient management
5. 成人における亜急性および慢性咳嗽の治療 treatment of subacute and chronic cough in adults

English Journal

Multiple granulomatous inflammation in the minor salivary glands: a proposed new entity, allergic granulomatous sialadenitis.

Irié T1, Maeda Y, Aida T, Sumitani K, Nagumo M, Tachikawa T.
Pathology international.Pathol Int.2004 Nov;54(11):850-3.
We report a patient who presented with multiple small submucosal nodules with granulomatous inflammation in the minor salivary glands of the oral cavity. A 43-year-old woman presented with a 1-week history of multiple small submucosal nodules in her oral cavity after having taken medicine for abdomi
PMID 15533228

Eosinophilic pustular folliculitis induced by allopurinol and timepidium bromide.

Maejima H, Mukai H, Hikaru E.
Acta dermato-venereologica.Acta Derm Venereol.2002;82(4):316-7.
PMID 12361147

[Comparative study of effects of gastrointestinal-motility control agents on rats and human colon].

Sasaki D, Kawakami S, Yoshida Y.
Nihon Heikatsukin Gakkai zasshi.Nihon Heikatsukin Gakkai Zasshi.1990 Apr;26(2):85-8.
PMID 2273693

Japanese Journal

後発医薬品の製剤学的同等性の検討(2)

高橋修二,豊口禎子,東海林徹,仲川義人
病院薬学 23(5), 431-436, 1997-10-10
… e. timepidium bromide and ketotifen fumarate. … However, significant differences were found among the products in the dissolution test for timepidium bromide. …
NAID 110001799683

Ｔｉｑｕｉｚｉｕｍ　ｂｒｏｍｉｄｅ（ＨＳＲ‐９０２）の抗潰よう薬としての評価

森川宏二 [他],荒谷隆幸,水谷藤恵,加藤日出男,伊藤安夫
日本薬理学雑誌 90(5), 273-283, 1987
… 抗ムスカリン作用薬であるtiquizium bromide (HSR-902)の各種胃・十二指腸損傷，胃液分泌，瞳孔径ならびに唾液分泌に対する作用をラットを用いて検討し，その作用を，抗潰瘍薬であるpirenzepine・2HCl(pirenzepine)あるいは鎮痙薬であるtimepidium bromide (timepidium)と比較した．1)HSR-902は10～100mg/kgの経口投与により，水浸ストレス，aspirin，indomethacin，serotoninおよびreserplneによ …
NAID 130000759425

腎・尿管結石に対する臭化チメピジウム(SA-504)細粒の使用経験

松田聖士,村中幸二,酒井俊助,清水保夫
泌尿器科紀要 30(6), 845-848, 1984-06
… Ninety mg per day of timepidium bromide subtle granules was given orally to 17 patients with renal or ureteral calculi for no less than fourteen days. …
NAID 120002158726

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★リンクテーブル★

リンク元	「チメピジウム」
拡張検索	「timepidium bromide hydrate」
関連記事	「bromide」「timepidium」「bromides」

「チメピジウム」

Timepidium bromide
Systematic (IUPAC) name
	3-(di-2-thienylmethylene)-5-methoxy-1,1-dimethylpiperidinium bromide
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	SC, IM, IV
Identifiers
CAS number	35035-05-3
ATC code	A03AB19
PubChem	CID 160243
UNII	8R9E4766V4
Chemical data
Formula	C17H22BrNOS2
Mol. mass	400.39 g/mol
	SMILES C[N+]1(CC(CC(=C(C2=CC=CS2)C3=CC=CS3)C1)OC)C.[Br-];
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