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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/28 06:29:23」(JST)

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1. 止血の概要 overview of hemostasis
2. 血栓溶解異常による血栓性および出血性疾患 thrombotic and hemorrhagic disorders due to abnormal fibrinolysis
3. 第ⅩＩ因子欠乏症 factor xi deficiency
4. 外傷に伴う凝固障害 coagulopathy associated with trauma
5. 静脈血栓症の原因の概要 overview of the causes of venous thrombosis

Effect of single nucleotide polymorphism in thrombin-activatable fibrinolysis inhibitor on the risk of diabetic macrovascular disease.

Zheng C1, Li X, Kong C, Ke S, Peng C, Cui T, Gao M, Zhou Y, Guo W, Huang L, Petersen RB, Huang K.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.Blood Coagul Fibrinolysis.2014 Nov 13. [Epub ahead of print]
Hypofibrinolysis is commonly found in patients with diabetes mellitus and is associated with the increased risk for many diabetic complications. An important inhibitor of fibrinolysis, thrombin-activatable fibrinolysis inhibitor (TAFI), participates in hypofibrinolysis in diabetes mellitus and may b
PMID 25396763

Effects of a TAFI-Inhibitor Combined with a Suboptimal Dose of rtPA in a Murine Thromboembolic Model of Stroke.

Durand A1, Chauveau F, Cho TH, Kallus C, Wagner M, Boutitie F, Maucort-Boulch D, Berthezène Y, Wiart M, Nighoghossian N.
Cerebrovascular diseases (Basel, Switzerland).Cerebrovasc Dis.2014 Nov 13;38(4):268-275. [Epub ahead of print]
Background: Since thrombolysis is the only approved intervention for ischemic stroke, improving its efficacy and safety is a therapeutic aim of considerable interest. The activated form of thrombin activatable fibrinolysis inhibitor (TAFI) has antifibrinolytic effects, and inhibition of TAFI might t
PMID 25401979

Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation.

Rancourt RC1, Ahmad A, Veress LA, Rioux JS, Garlick RB, White CW.
American journal of respiratory cell and molecular biology.Am J Respir Cell Mol Biol.2014 Oct;51(4):559-67. doi: 10.1165/rcmb.2014-0012OC.
Acute lung injury in response to mustard gas (sulfur mustard [SM]) inhalation results in formation of fibrin casts, which obstruct the airway. The objective of this study was to identify fibrinolytic pathways that could be contributing to the persistence of airway casts after SM exposure. Rats were
PMID 24796565

三浦徳,細野崇,関泰一郎
日本血栓止血学会誌 25(4), 512-515, 2014
Points①TAF（I 56 kDa）は，活性化ペプチド（Phe1-Arg92; 20 kDa）と触媒ドメイン（Ala93-Val401; 36 kDa）から構成されている．②活性化ペプチドは，4 つのβシートと2 つのαヘリックスからなるα/βサンドイッチ構造（Phe1-Val76），部分的にαヘリックス構造を形成したリンカー領域（Gln77-Arg92）に分けられる．③トロンビンはArg92 …
NAID 130004687767

Increase in plasma thrombin-activatable fibrinolysis inhibitor may not contribute to thrombotic tendency in antiphospholipid syndrome because of inhibitory potential of antiphospholipid antibodies toward TAFI activation

IEKO Masahiro,YOSHIDA Mika,NAITO Sumiyoshi,NAKABAYASHI Toru,KANAZAWA Kaoru,MIZUKAMI Kazuhiro,MUKAI Masaya,ATSUMI Tatsuya,KOIKE Takao
International journal of hematology 91(5), 776-783, 2010-06-15
… Objective: To clarify the mechanism, we measured plasma levels of thrombin-activatable fibrinolysis inhibitor (TAFI) in APS patients. … Methods and Results: Both the TAFI antigen (TAFI:Ag) level measured with an ELISA, and thrombin-thrombomodulin-dependent TAFI activity (TAFI:Ac) were elevated in 68 APS patients as compared with those in 66 healthy controls, though they were lower than those in 46 patients with autoimmune diseases. …
NAID 10026511025