terminal deoxynucleotide transferase

出典: meddic

ターミナルデオキシヌクレオチジルトランスフェラーゼ TdT


  • Assessment of the viability of embryos stored in liquid nitrogen produced commercially using culture medium as a complementary test for stereoscopic microscopy.
  • Godinez B, Galina CS, Leon H, Gutierrez M, Moreno-Mendoza N.SourceDepartamento de Reproducción Animal Facultad de Medicina Veterinaria y Zootecnia, Universidad, Nacional Autónoma de México, Mexico.
  • Zygote (Cambridge, England).Zygote.2013 May;21(2):110-4. doi: 10.1017/S0967199411000669. Epub 2011 Nov 9.
  • Summary The objective of the present study was to evaluate the viability of frozen embryos obtained from various private farmers in a culture medium for 4 h. Forty-seven embryos were used that had been previously graded as good and fair. These embryos were evaluated using stereoscopic microscopy by
  • PMID 22067745
  • Changes in DNA fragmentation during sperm preparation for intracytoplasmic sperm injection over time.
  • Rougier N, Uriondo H, Papier S, Checa MA, Sueldo C, Alvarez Sedó C.SourceCEGYR-Reproductive Medicine, Buenos Aires, Argentina; Department of Obstetrics and Gynecology, Parc de Salut Mar, Universitat Autonoma de Barcelona, Barcelona, Spain.
  • Fertility and sterility.Fertil Steril.2013 Apr 2. pii: S0015-0282(13)00406-8. doi: 10.1016/j.fertnstert.2013.03.005. [Epub ahead of print]
  • OBJECTIVE: To compare the DNA fragmentation of semen samples established by terminal deoxynucleotide transferase-mediated dUTP nick-end labeling (TUNEL) after incubation in polyvinylpyrrolidone (PVP) and hyaluronic acid (HA) for different time periods.DESIGN: Comparative prospective study.SETTING: C
  • PMID 23561542
  • Mystery of idiopathic male infertility: is oxidative stress an actual risk?
  • Aktan G, Doğru-Abbasoğlu S, Küçükgergin C, Kadıoğlu A, Ozdemirler-Erata G, Koçak-Toker N.SourceDepartment of Urology, Istanbul Medical Faculty, Istanbul University, Çapa, Istanbul, Turkey.
  • Fertility and sterility.Fertil Steril.2013 Apr;99(5):1211-5. doi: 10.1016/j.fertnstert.2012.11.045. Epub 2012 Dec 17.
  • OBJECTIVE: To study the role of oxidative stress in sperm dysfunction in Turkish idiopathic infertile men.DESIGN: Prospective study.SETTING: Medical laboratory.PATIENT(S): Semen samples from 28 idiopathic infertile men and 14 fertile men.INTERVENTION(S): Sperm DNA fragmentation and reactive oxygen s
  • PMID 23254182


  • Apoptosis-inducing Activity of Hot Water Extracts from the Sea Cucumber in Human Colon Tumor Cells
  • OGUSHI Mariko,YOSHIE STARK Yumiko,SUZUKI Takeshi
  • Food science and technology research 12(4), 290-294, 2006-11-01
  • … We demonstrated the induction of apoptosis using phosphatidylserine translocation (APOPercentage Assay kit), terminal deoxynucleotide transferase-mediated dUTP-biotin nick-end labeling (TUNEL), and DNA fragmentation observed as DNA ladder. …
  • NAID 10018441263
  • Calcium Antagonist Inhibits Glomerular Cell Apoptosis and Injuries of L-NAME Exacerbated Nephrosclerosis in SHR.
  • WATANABE Shigeko,ONO Hidehiko,ISHIMITSU Toshihiko,MATSUOKA Hiroaki,ONO Yuko,FUJIMORI Takahiro
  • Hypertension Research 23(6), 683-691, 2000
  • … Apoptosis in non-sclerotic glomeruli was quantified by terminal deoxynucleotide transferase-mediated dUTP nick-end labeling. …
  • NAID 130003456487




関連記事terminal」「transferase」「deoxynucleotide transferase」「deoxynucleotide」「transferases



terminal deoxynucleotidyl transferase, TdT
  • lymphoi-speciic emzyme
  • adds nucleotides randomly to the single-strand ends.
  • TCRやBCRの各鎖をコードする遺伝子のV,D,Jセグメントの遺伝子再構成において、altermisによってニックが入った末端はヌクレアーゼやTdTにより塩基が付与されたりする。これによって多様性が生じる


  [★] ターミナルデオキシヌクレオチジルトランスフェラーゼ terminal deoxynucleotidyl transferase




terminal deoxynucleotide transferase



  • n.
  • adj.
  • 終端の、終末の、末期の
distalendend stageendingextremityfull-blownterminal regionterminal stageterminallyterminiterminus

WordNet   license wordnet

「relating to or occurring in a term or fixed period of time; "terminal examinations"; "terminal payments"」

PrepTutorEJDIC   license prepejdic

「『終りの』,末端の / 毎期の,定期の;学期末の / 『死に至る』, / 末端 / (電池の)端子 / (町の中心に近い)空港バス発着場;(一般に,鉄道・バスの)終点,終着駅」

WordNet   license wordnet

「a contact on an electrical device (such as a battery) at which electric current enters or leaves」

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「station where transport vehicles load or unload passengers or goods」
terminus, depot

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「electronic equipment consisting of a device providing access to a computer; has a keyboard and display」

WordNet   license wordnet

「being or situated at an end; "the endmost pillar"; "terminal buds on a branch"; "a terminal station"; "the terminal syllable"」

WordNet   license wordnet

「causing or ending in or approaching death; "a terminal patient"; "terminal cancer"」

WordNet   license wordnet

「of or relating to or situated at the ends of a delivery route; "freight pickup is a terminal service"; "terminal charges"」



  • n.

WordNet   license wordnet

「any of various enzymes that move a chemical group from one compound to another compound」

deoxynucleotide transferase」


terminal deoxynucleotide trans ferase (TdT)





  [★] トランスフェラーゼ