spinal cord neoplasm

脊髄腫瘍、脊髄新生物

関

spinal cord tumor

WordNet

1. work natural fibers into a thread; "spin silk"
2. prolong or extend; "spin out a visit" (同)spin out
3. the act of rotating rapidly; "he gave the crank a spin"; "it broke off after much twisting" (同)twirl, twist, twisting, whirl
4. a distinctive interpretation (especially as used by politicians to sway public opinion); "the campaign put a favorable spin on the story"
5. a short drive in a car; "he took the new car for a spin"
6. a swift whirling motion (usually of a missile)
7. revolve quickly and repeatedly around ones own axis; "The dervishes whirl around and around without getting dizzy" (同)spin around, whirl, reel, gyrate
8. form a web by making a thread; "spiders spin a fine web"
9. make up a story; "spin a yarn"
10. stream in jets, of liquids; "The creek spun its course through the woods"
11. twist and turn so as to give an intended interpretation; "The Presidents spokesmen had to spin the story to make it less embarrassing"
12. stack in cords; "cord firewood"
13. a unit of amount of wood cut for burning; 128 cubic feet
14. a cut pile fabric with vertical ribs; usually made of cotton (同)corduroy
15. a light insulated conductor for household use (同)electric cord
16. a line made of twisted fibers or threads; "the bundle was tied with a cord"
17. bind or tie with a cord
18. of or relating to the spine or spinal cord; "spinal cord"; "spinal injury"

PrepTutorEJDIC

1. (羊毛などから)〈糸など〉‘を'『紡ぐ』《+『名』+『out of』+『名』〈羊毛〉》,(糸などに)〈羊毛など〉‘を'紡ぐ《+『名』〈羊毛〉+『into』+『名』》 / 〈クモ・カイコなどが〉〈糸〉‘を'『吐く』;〈巣・繭〉‘を'かける / …‘を'くるくる回す / 〈物語など〉‘を'作る,話す / 『糸を紡ぐ』;〈クモ・カイコなどが〉糸を吐く / 〈こまなどが〉くるくる回る / 〈車などが〉疾走する / 〈頭などが〉くらくらする / 〈C〉〈U〉くるくる回すこと;回転 / 〈C〉《単数形で》(車などの)一走り / 〈C〉(飛行機の)きりもみ降下 / 〈C〉《単数形で》(価値などの)急落
2. 〈U〉〈C〉『綱,ひも』(stringより太くropeより細い) / 〈U〉〈C〉束縛,きずな / 〈C〉〈U〉(電気の)『コード』,線 / (またchord)〈C〉(動物体の)索状組織,腱(けん) / 〈C〉うね織り,(特に)コールテン;(うね織りの)うね;《複数形で》コールテンのズボン / 〈C〉コード(材木の容積の単位で約6.25m) / …'を'綱(ひも)で縛る
3. 背骨の / せき髄麻酔
4. (体内にできる)新生物;腫瘍(しゅよう)
5. (驚いて)わあっ,えっ

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/09/20 10:49:47」(JST)

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[Wiki en表示]

Spinal tumors
Classification and external resources
Specialty	oncology
ICD-10	C72.0
ICD-9-CM	192.2
DiseasesDB	31483
MedlinePlus	001403
eMedicine	orthoped/49 med/2993, radio/169
MeSH	C04.557.465.220

Spinal tumors are neoplasms located in the spinal cord. Extradural tumors are more common than intradural neoplasms.

Depending on their location, the spinal cord tumors can be:

• Extradural - outside the dura mater lining (most common)
• Intradural - part of the dura
  • Intramedullary - inside the spinal cord
  • Extramedullary- inside the dura, but outside the spinal cord

Pathology

Extradural tumors are mostly metastases from primary cancers elsewhere (commonly breast, prostate and lung cancer). Intradural tumours can be classified as intramedullary (within the spinal parenchyma) or extramedullary (within the dura, but outside the spinal parenchyma). Extramedullary tumours are more common than intramedullary tumours. Common extramedullary tumours include meningiomas, schwannomas, extramedullary ependymomas, haemangioblastomas, while intramedullary tumours include astrocytomas and intramedullary ependymomas.

Symptoms

Pain is the most common symptom at presentation. The symptoms seen are due to spinal nerve compression and weakening of the vertebral structure. Incontinence and decreased sensitivity in the saddle area (buttocks) are generally considered warning signs of spinal cord compression by the tumor. Other symptoms of spinal cord compression include lower extremity weakness, sensory loss,numbness in hands and legs and rapid onset paralysis. The diagnosis of primary spinal cord tumors is very difficult, mainly due to its symptoms, which tend to be wrongly attributed to more common and benign degenerative spinal diseases.

Spinal cord compression is commonly found in patients with metastatic malignancy. Back pain is a primary symptom of spinal cord compression in patients with known malignancy. It may prompt a bone scan to confirm or exclude spinal metastasis. Rapid identification and intervention of malignant spinal tumors, often causing spinal cord compression, is key to maintaining quality of life in patients.

Diagnosis

The diagnosis of primary spinal cord tumors is difficult, mainly due to their symptoms, which in early stages mimic more common and benign degenerative spinal diseases. MRI and bone scanning are used for diagnostic purposes. This assesses not only the location of the tumor(s) but also their relationship with the spinal cord and the risk of cord compression.

Treatment

• Steroids (e.g. corticosteroids) may be administered if there is evidence of spinal cord compression. These do not affect the tumoral mass itself, but tend to reduce the inflammatory reaction around it, and thus decrease the overall volume of the mass impinging on the spinal cord.
• Radiotherapy may be administered to patients with malignant tumors. Radiation is usually delivered to the involved segment in the spinal cord as well as to the uninvolved segment above and below the involved segment.
• Surgery is sometimes possible. The goals of surgical treatment for spinal tumors can include histologic diagnosis, tumor local control or oncological cure, pain relief, spinal cord decompression and restoration of neurological function, restoration of spine stability, and deformity rectification. Extramedullary tumours are more amenable to resection than intramedullary tumours.
• The combination of minimally invasive surgery and radiation or chemotherapy is a new technique for treating spinal tumors. This treatment can be tailored to the particular tumor of the spine, either metastatic or primary.

numbness in the legs and arms, Some suggest that direct decompressive surgery combined with postoperative radiotheranumbness in the legs and arms,py provide better outcomes than treatment with radiotherapy alone for patients with spinal cord compression due to metastatic cancer. It is also important to take into consideration the prognosis of the patients and their ambulation status at diagnosis, and treat accordingly.

References

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 脊髄腫瘍 spinal cord tumors
• 2. 小児における中枢神経系腫瘍の臨床症状および診断 clinical manifestations and diagnosis of central nervous system tumors in children
• 3. 馬尾症候群などの腫瘍による硬膜外脊髄圧迫の臨床的特徴および診断 clinical features and diagnosis of neoplastic epidural spinal cord compression including cauda equina syndrome
• 4. 小児における中枢神経系腫瘍の疫学 epidemiology of central nervous system tumors in children
• 5. 血管芽細胞腫 hemangioblastoma

English Journal

• Comparison of intensity modulated radiotherapy with simultaneous integrated boost (IMRT-SIB) and a 3-dimensional conformal parotid gland-sparing radiotherapy (ConPas 3D-CRT) in treatment of nasopharyngeal carcinoma: a mono-institutional experience.

• Bišof V1,2, Rakušić Z3,4, Bibić J3, Grego T3, Soče M3.
• La Radiologia medica.Radiol Med.2018 Mar;123(3):217-226. doi: 10.1007/s11547-017-0824-9. Epub 2017 Nov 1.
• PMID 29094268

• A rare case of spinal cord compression due to cervical spine metastases from paraganglioma of the jugular foramen-how should it be treated?

• Kapetanakis S1, Chourmouzi D2, Gkasdaris G3, Katsaridis V4, Eleftheriadis E5, Givissis P6.
• Journal of surgical case reports.J Surg Case Rep.2018 Feb 3;2018(2):rjy005. doi: 10.1093/jscr/rjy005. eCollection 2018 Feb.
• PMID 29423169

• Comparison of Two Radiotherapy Regimens for Metastatic Spinal Cord Compression: Subgroup Analyses from a Randomized Trial.

• Rades D1, Conde-Moreno AJ2, Cacicedo J3, Šegedin B4, Stanic K4, Metz M5, Rudat V6, Schild SE7.
• Anticancer research.Anticancer Res.2018 Feb;38(2):1009-1015.
• PMID 29374734

Japanese Journal

• 脊椎骨腫瘍の塞栓術

• 日本インターベンショナルラジオロジー学会雑誌 30(3), 235-241, 2015
• NAID 130005113950

• Melanotic Schwannoma of the Cervicall Spine Progressing With Pulmonary Metastasis : Case Report

• Neurologia medico-chirurgica = 神経外科 53(10), 712-716, 2013-10-15
• NAID 10031191643

• Myxopapillary Ependymoma in the Third Ventricle Area and Sacral Canal : Dropped or Retrograde Metastasis? -Case Report-

• Neurologia medico-chirurgica = 神経外科 53(4), 237-241, 2013-04-15
• NAID 10031151338

Related Links

• Spinal Cord Neoplasms - Diseases & Conditions - Medscape ...

Neoplastic disease that involves the spine with spinal cord compression may be devastating. Primary spinal cord tumors arise from the different elements of the CNS, including neurons, supporting glial cells, and ...

• Disease | Genetic and Rare Diseases Information Center ...

FDA-Approved Treatments The medication(s) listed below have been approved by the Food and Drug Administration (FDA) as orphan products for treatment of this ... ClinicalTrials.gov lists trials that are studying or have studied Spinal ...

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★リンクテーブル★

リンク元	「spinal cord tumor」「脊髄新生物」
関連記事	「cord」「spinal」「neoplasm」「cor」「spin」

「spinal cord tumor」

　　[★]

脊髄腫瘍

関

spinal cord neoplasm

同

脊髄腫瘍

「脊髄新生物」

　　[★]

英

spinal cord neoplasm

関

脊髄腫瘍

「cord」

　　[★]

• n.

• コード、ひも、索、腱

関

chorda、chordae、chordal、code、tendon、trabecula、trabeculae

　 　 　 　 　 　 　

「spinal」

　　[★]

• adj.

• 脊髄の、脊髄性の、脊柱の

関

dorsal spine、rachis、spinal column、spinal cord、spine、vertebral column

　 　

「neoplasm」

　　[★]

• n.

• 新生物、腫瘍

関

benign neoplasm、cancer、neoplasia、neoplastic、onco、oncologic、tumor、tumour

　

「cor」

　　[★]

• n. (pl. cordia

• 心臓

関

(n.)precordia 前胸部、(adj.)precordial 前胸部の

　

「spin」

　　[★]

• スピン