WordNet

hand over one and receive another, approximately equivalent; "exchange prisoners"; "exchange employees between branches of the company"
chemical process in which one atom or ion or group changes places with another
reciprocal transfer of equivalent sums of money (especially the currencies of different countries); "he earns his living from the interchange of currency" (同)interchange
the act of changing one thing for another thing; "Adam was promised immortality in exchange for his disobedience"; "there was an interchange of prisoners" (同)interchange
(chess) gaining (or losing) a rook in return for a knight or bishop; "black lost the exchange"
(chess) the capture by both players (usually on consecutive moves) of pieces of equal value; "the endgame began after the exchange of queens"
a workplace for buying and selling; open only to members
the act of giving something in return for something received; "deductible losses on sales or exchanges of property are allowable"
a mutual expression of views (especially an unpleasant one); "they had a bitter exchange"
give to, and receive from, one another; "Would you change places with me?"; "We have been exchanging letters for a year" (同)change, interchange
a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
a nonmetallic univalent element that is normally a colorless and odorless highly flammable diatomic gas; the simplest and lightest and most abundant element in the universe (同)H, atomic number 1
one whose business is to exchange the money of one country for that of another country (同)money changer

PrepTutorEJDIC

…‘を'『取り替える』;(…と)…‘を'取り替える《+『名』+『for』+『名』》 / …‘を'『取り交わす』;(人と)…‘を'取り交わす《+『名』+『with』+『名』〈人〉》 / (化幣が)両替される / 〈U〉〈C〉(物の物との)『取り替え』《+『of』+『名』+『for』+『名』》;(相手と物を)『交換すること』《+『of』+『名』(複数)+『with』+『名』〈人〉》 / 〈C〉交換物,取り替え品 / 〈C〉取引所;(電話の)交換局 / 〈U〉両替;為替(かわせ),為替相場 / 〈C〉=employment exchange
ソジウム,ナトリウム(金属元素;化学記号はNa)
『水素』(化学記号は『H』)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/01/13 05:32:30」(JST)

wiki en

[Wiki en表示]

The sodium–hydrogen antiporter or sodium–hydrogen exchanger is a membrane protein found in many cells, and especially in those of the nephron of the kidney. Specifically in the intercalary cells of the collecting duct. The membrane pump is primarily responsible for maintaining the balance of sodium.^[1]

Isoforms

There are several isoforms of the antiporter:

Sodium–hydrogen antiporter 1
Sodium–hydrogen antiporter 2
Sodium–hydrogen antiporter 3
Sodium–hydrogen antiporter 5
Sodium–hydrogen antiporter 6
Sodium–hydrogen antiporter 8

References

^ VI. Mechanisms of Salt & Water Reabsorption

External links

Sodium-Hydrogen Exchanger at the US National Library of Medicine Medical Subject Headings (MeSH)

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

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1. 赤血球水分量の制御 control of red blood cell hydration
2. 幼児および小児における尿細管性アシドーシスの病因および臨床症状 etiology and clinical manifestations of renal tubular acidosis in infants and children
3. 心臓の虚血性再潅流障害 ischemic reperfusion injury of the heart
4. 低リン血症の原因 causes of hypophosphatemia
5. 利尿剤によって誘発された高尿酸血症および痛風 diuretic induced hyperuricemia and gout

English Journal

Expression of sodium/hydrogen exchanger 3 and cation-chloride cotransporters in the kidney of Japanese eel acclimated to a wide range of salinities.

Teranishi K, Mekuchi M, Kaneko T.SourceDepartment of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan. Electronic address: teranishi@marine.fs.a.u-tokyo.ac.jp.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.Comp Biochem Physiol A Mol Integr Physiol.2013 Feb;164(2):333-43. doi: 10.1016/j.cbpa.2012.11.011. Epub 2012 Nov 21.
Reabsorption of monovalent ions in the kidney is essential for adaptation to freshwater and seawater in teleosts. To assess a possible role of Na(+)/H(+) exchanger 3 (NHE3) in renal osmoregulation, we first identified a partial sequence of cDNA encoding NHE3 from the Japanese eel kidney. For compari
PMID 23178812

Gastrin Induces Sodium-Hydrogen Exchanger 3 Phosphorylation and mTOR Activation via a Phosphoinositide 3-Kinase-/Protein Kinase C-Dependent but AKT-Independent Pathway in Renal Proximal Tubule Cells Derived From a Normotensive Male Human.

Liu T, Jose PA.SourceMD, PhD, or Tianbing Liu, PhD, Center for Molecular Physiology Research, Children's Research Institute, Children's National Medical Center, 111 Michigan Avenue, Washington, DC 20010. pjose@medicine.umaryland.edu; or tianbingliu@uwalumni.com.
Endocrinology.Endocrinology.2013 Feb;154(2):865-75. doi: 10.1210/en.2012-1813. Epub 2012 Dec 28.
Gastrin is natriuretic, but its renal molecular targets and signal transduction pathways are not fully known. In this study, we confirmed the existence of CCKBR (a gastrin receptor) in male human renal proximal tubule cells and discovered that gastrin induced S6 phosphorylation, a downstream compone
PMID 23275470

Quinine Treatment Selects the pfnhe-1 ms4760-1 Polymorphism in Malian Patients with Falciparum Malaria.

Kone A, Mu J, Maiga H, Beavogui AH, Yattara O, Sagara I, Tekete MM, Traore OB, Dara A, Dama S, Diallo N, Kodio A, Traoré A, Björkman A, Gil JP, Doumbo OK, Wellems TE, Djimde AA.SourceMalaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy, and Odonto-Stomatology, University of Science, Techniques and Technology, Bamako, Mali.
The Journal of infectious diseases.J Infect Dis.2013 Feb;207(3):520-7. doi: 10.1093/infdis/jis691. Epub 2012 Nov 16.
Background. The mechanism of Plasmodium falciparum resistance to quinine is not known. In vitro quantitative trait loci mapping suggests involvement of a predicted P. falciparum sodium-hydrogen exchanger (pfnhe-1) on chromosome 13. Methods. We conducted prospective quinine efficacy studies in 2
PMID 23162138

Japanese Journal

Estrogen-dependent regulation of sodium/hydrogen exchanger-3 (NHE3) expression via estrogen receptor β in proximal colon of pregnant mice

Choijookhuu Narantsog,Sato Yoko,Nishino Tomoya,Endo Daisuke,Hishikawa Yoshitaka,Koji Takehiko
Histochemistry and Cell Biology 137(5), 575-587, 2012-05
… These results indicate that ERβ regulates the expression of NHE3 in the proximal colon of pregnant mice through estrogen action, suggesting the involvement of increased sodium absorption by up-regulated NHE3 in constipation during pregnancy. …
NAID 120004814258

Genomic structure and sequence of a chicken homolog (chNthl1) of Escherichia coli endonuclease III with those of the adjacent parts of chTsc2 and chSlc9a3r2 genes

Seki Shuji,Sarker Altaf H.,Nakamura Takashi,Seki Yuichi,Ikeda Shogo
Chugokugakuen journal 6, 23-27, 2007
… Downstream of the chNthl1 gene, the gene for the regulatory factor 2 (chSlc9a3r2) of the solute carrier family 9 (sodium/hydrogen exchanger), isoform A3, lies in a 3'-to-3' orientation. …
NAID 110007124424

Effects of [5-(2-Methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32560), a Novel Sodium/Hydrogen Exchanger-1 Inhibitor, on Myocardial Infarct Size and Ventricular Arrhythmias in a Rat Model of Ischemia/Reperfusion Heart Injury

Park Jung-Woo,Roh Hui-Yul,Jung In-Sang [他],YUN Yeo-Pyo,YI Kyu-Yang,YOO Sung-Eun,KWON Suk-Hyung,CHUNG Hun-Jong,SHIN Hwa-Sup
Journal of pharmacological sciences 98(4), 439-449, 2005-08-20
… The cardioprotective effects of the novel sodium/hydrogen exchanger-1 (NHE-1) inhibitor KR-32560 {[5-(2-methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine} were studied in an anesthetized rat model of 30-min ischemia / 2.5-h reperfusion heart injury. …
NAID 10025729772

Related Pictures

★リンクテーブル★

リンク元	「sodium-hydrogen antiporter」「Na+/H+交換輸送体」「Na-H exchanger」「Na-H antiporter」「Na+-H+ exchanger」
関連記事	「exchange」「exchanger」