出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/03/31 12:30:31」(JST)[Wiki en表示]
- Lovastatin-Mediated Changes in Human Tendon Cells.
- Kuzma-Kuzniarska M1, Cornell HR1, Moneke MC1, Carr AJ1, Hulley PA1.
- Journal of cellular physiology.J Cell Physiol.2015 Oct;230(10):2543-51. doi: 10.1002/jcp.25010.
- Statins are among the most widely prescribed drugs worldwide. Numerous studies have shown their beneficial effects in prevention of cardiovascular disease through cholesterol-lowering and anti-atherosclerotic properties. Although some statin patients may experience muscle-related symptoms, severe si
- PMID 25846724
- Mitochondria to nucleus signaling and the role of ceramide in its integration into the suite of cell quality control processes during aging.
- Jazwinski SM1.
- Ageing research reviews.Ageing Res Rev.2015 Sep;23(Pt A):67-74. doi: 10.1016/j.arr.2014.12.007. Epub 2014 Dec 31.
- Mitochondria to nucleus signaling has been the most extensively studied mode of inter-organelle communication. The first signaling pathway in this category of information transfer to be discovered was the retrograde response, with its own set of signal transduction proteins. The finding that this pa
- PMID 25555678
- Calcium is an organizer of cell polarity in plants.
- Himschoot E1, Beeckman T2, Friml J3, Vanneste S4.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Sep;1853(9):2168-2172. doi: 10.1016/j.bbamcr.2015.02.017. Epub 2015 Feb 25.
- Cell polarity is a fundamental property of pro- and eukaryotic cells. It is necessary for coordination of cell division, cell morphogenesis and signaling processes. How polarity is generated and maintained is a complex issue governed by interconnected feed-back regulations between small GTPase signa
- PMID 25725133
- 西田 基宏,外山 喬士,熊谷 嘉人,沼賀(冨田) 拓郎
- YAKUGAKU ZASSHI 134(12), 1239-1243, 2014
- … The switching mechanism of NO-mediated signaling includes formation of endogenous NO-derived electrophilic byproducts such as 8-nitroguanosine 3′,5′-cyclic monophosphate (8-nitro-cGMP), which selectively targets an oncogenic small GTPase H-Ras at Cys-184, leading to cardiac cell senescence via covalent modification (S-guanylation) and activation of H-Ras. …
- NAID 130004712987
- RhoJ defines angiogenic endothelial cell motility by integrating VEGF and Sema3E signals
- Uemura Akiyoshi,Fukushima Yoko,Nishiyama Koichi,Ogura Yuichiro,Nishikawa Shin-Ichi
- Microvascular Reviews and Communications 7(1), 37-37, 2014
- … Here, we show that the small GTPase RhoJ is an EC-intrinsic integrator of VEGF and Sema3E signals. …
- NAID 130004678475
- Epigallocatechin gallate suppresses LPS endocytosis and nitric oxide productionby reducing Rab5-caveolin-1 interaction
- HAGIWARA Makoto,MATSUSHITA Kenji
- Biomedical Research 35(2), 145-151, 2014
- … We also investigated themechanism with focus on the effect of EGCG on interaction between small GTPase Rab5 and caveolin-1. …
- NAID 130004470860
- Small GTPases (EC 18.104.22.168) are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP). They are a type of G-proteins found in the cytosol that are homologous to the alpha subunit of heterotrimeric ...
- Most Small GTPases Are Highly Conserved Regulators of Intracellular Trafficking The small GTPase superfamily is divided into at least five families, including Ras, Rho, Rab, Arf, and Ran (Bischoff et al., 1999; Takai et al., 2001). The ...
- small guanosine triphosphatase、small GTPase