retinoblastoma

出典: meddic

網膜芽細胞腫

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「malignant ocular tumor of retinal cells; usually occurs before the third year of life; composed of primitive small round retinal cells」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/14 23:16:45」(JST)

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英文文献

  • CDK4/6 inhibitors in breast cancer.
  • Dukelow T1, Kishan D, Khasraw M, Murphy CG.
  • Anti-cancer drugs.Anticancer Drugs.2015 Sep;26(8):797-806. doi: 10.1097/CAD.0000000000000249.
  • Deregulation of the cyclin-dependent kinase (CDK) 4/6-retinoblastoma (RB) axis can occur through a number of mechanisms and contributes towards the unrestrained growth witnessed in a variety of cancers including breast cancers. Recent years have seen the development of selective CDK4/6 inhibitors, w
  • PMID 26053278
  • Universal ocular screening of 1021 term infants using wide-field digital imaging in a single public hospital in India - a pilot study.
  • Vinekar A1, Govindaraj I1, Jayadev C1, Kumar AK1, Sharma P1, Mangalesh S1, Simaldi L2, Avadhani K1, Shetty B1, Bauer N3.
  • Acta ophthalmologica.Acta Ophthalmol.2015 Aug;93(5):e372-6. doi: 10.1111/aos.12685. Epub 2015 Feb 26.
  • PURPOSE: Universal eye screening of neonates is currently not standard of care. Early detection of abnormalities could offer prompt management and a reduction in visual morbidity. We report a pilot study using wide-field digital imaging to screen all infants at birth to explore its feasibility as a
  • PMID 25721891
  • Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells.
  • Takebayashi S1,2, Tanaka H1, Hino S1, Nakatsu Y1, Igata T1, Sakamoto A1, Narita M3, Nakao M1,2,4.
  • Aging cell.Aging Cell.2015 Aug;14(4):689-97. doi: 10.1111/acel.12351. Epub 2015 May 25.
  • Metabolism is closely linked with cellular state and biological processes, but the mechanisms controlling metabolic properties in different contexts remain unclear. Cellular senescence is an irreversible growth arrest induced by various stresses, which exhibits active secretory and metabolic phenoty
  • PMID 26009982

和文文献

  • 腫瘍(網膜芽細胞腫を含む) (特集 小児眼科診療のコツと注意点)
  • 網膜芽細胞腫の患児と家族の看護に関する国内文献の検討
  • 永吉 美智枝,廣瀬 幸美
  • 小児保健研究 = The journal of child health 74(4), 579-587, 2015-07
  • NAID 40020545496
  • 知っておきたい小児眼科の最新知識(7)これだけは知っておきたい網膜芽細胞腫治療の最新知識

関連リンク

Retinoblastoma (Rb) is a rapidly developing cancer that develops in the cells of retina, the light-detecting tissue of the eye. In the developed world, Rb has one of the best cure rates of all childhood cancers (95-98%), with more than nine out of ...

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★リンクテーブル★
リンク元網膜芽細胞腫」「sporadic retinoblastoma」「hereditary retinoblastoma」「eye tumor
拡張検索familial retinoblastoma」「retinoblastoma-like protein p130」「intraocular retinoblastoma

網膜芽細胞腫」

  [★]

retinoblastoma
内長性網膜芽細胞腫

概念

  • 網膜の悪性腫瘍

疫学

  • 発生頻度は1/20000
  • 通常、生後3年以内に発症。5歳以降ではまれ

病因

  • 1. 散発性
  • 2. 遺伝性:RB遺伝子の異常と関連(13q14)

病型

  • 家族性
両眼性で多発病巣
  • 孤発性
片眼性で単発病変

病態

  • 眼底に黄白色の腫瘤がみられ,周囲に網膜剥離を伴う

治療

放射線治療、レーザー光凝固、化学療法、眼球摘出など



sporadic retinoblastoma」

  [★]

散発性網膜芽細胞種

familial retinoblastomahereditary retinoblastomaretinoblastoma

hereditary retinoblastoma」

  [★]

遺伝性網膜芽細胞腫

familial retinoblastomaretinoblastomasporadic retinoblastoma


eye tumor」

  [★]

retinoblastoma
retinoblastoma


familial retinoblastoma」

  [★]

家族性網膜芽細胞腫

hereditary retinoblastomaretinoblastomasporadic retinoblastoma


retinoblastoma-like protein p130」

  [★] 網膜芽細胞腫様タンパク質p130


intraocular retinoblastoma」

  [★]

眼球内網膜芽細胞腫




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