renin-angiotensin-aldosterone system

出典: meddic

レニン-アンギオテンシン-アルドステロン系 RAAS

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/11/29 06:41:24」(JST)

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英文文献

  • Direct renin inhibitor ameliorates insulin resistance by improving insulin signaling and oxidative stress in the skeletal muscle from post-infarct heart failure in mice.
  • Fukushima A1, Kinugawa S2, Takada S1, Matsumoto J1, Furihata T1, Mizushima W1, Tsuda M1, Yokota T1, Matsushima S1, Okita K3, Tsutsui H1.
  • European journal of pharmacology.Eur J Pharmacol.2016 May 15;779:147-56. doi: 10.1016/j.ejphar.2016.03.022. Epub 2016 Mar 14.
  • Insulin resistance can occur as a consequence of heart failure (HF). Activation of the renin-angiotensin system (RAS) may play a crucial role in this phenomenon. We thus investigated the effect of a direct renin inhibitor, aliskiren, on insulin resistance in HF after myocardial infarction (MI). MI a
  • PMID 26988296
  • Nodular glomerulosclerosis and renin angiotensin system in Chinese patients with type 2 diabetes.
  • Wang M1, Zhang X1, Song X2, Zou X1, Wu W1, Wang Y1, Lin B1, Li R3, Hu F4, Zhao H5.
  • Molecular and cellular endocrinology.Mol Cell Endocrinol.2016 May 15;427:92-100. doi: 10.1016/j.mce.2016.03.008. Epub 2016 Mar 10.
  • BACKGROUND: Diabetic nephropathy (DN) is a multifactorial and polygenic disease with nodular glomerulosclerosis (NGS) pathognomonic for diabetes and hypertension. Patients with type 2 diabetes and hypertension have characteristic renin-angiotensin system (RAS) gene polymorphisms.METHODS AND RESULTS:
  • PMID 26973293
  • A Radical Sodium Reduction Policy Is Not Supported by Randomized Controlled Trials or Observational Studies: Grading the Evidence.
  • Graudal N1.
  • American journal of hypertension.Am J Hypertens.2016 May;29(5):543-8. doi: 10.1093/ajh/hpw006. Epub 2016 Jan 27.
  • Several health institutions recommend sodium intake be reduced to below 2,300mg, which means that 6-7 billion individuals should alter their diet to accommodate. Such a radical recommendation should be based on solid evidence. However, this review reveals that (i) there are no randomized controlled
  • PMID 26817656

和文文献

  • Hyperinsulinemia Leads the Elevation of Plasma Aldosterone Concentration Independently with Obesity, Dyslipidemia, and Insulin Resistance in Patients with Type 2 Diabetes Mellitus
  • Kimura Yuki,Matsui Jun,Matsumura Koki,Murakami Hiroshi,Yamashita Maki,Tanabe Jutaro,Murakami Hiroshi,Tamasawa Naoki,Daimon Makoto
  • 弘前医学 65(1), 35-42, 2014-04-15
  • … The study was to define plasma insulin level with the association of renin-angiotensin-aldosterone system activity in patients with type 2 diabetes. … Plasma aldosterone concentration(PAC) was signifi cantly higher in type 2 diabetics than that in non-diabetic subjects(10.4±4.9 vs. 7.4±3.7 ng/dl;p=0.004); … however plasma renin activity(PRA) did not diff er signifi cantly between the two groups. …
  • NAID 120005429840
  • 脳RAA系と認知機能 (特集 生活習慣病と認知機能 : 認知症の予防を見据えた生活習慣病の治療を目指して) -- (基礎知見)
  • hANP(カルペリチド) (特集 利尿薬およびそれに関連する話題)
  • 森 慶太,笠原 正登
  • 循環器内科 75(3), 280-287, 2014-03
  • NAID 40020021036

関連リンク

renin [re´nin] a proteolytic enzyme synthesized, stored, and secreted by the juxtaglomerular cells of the kidney; it plays a role in regulation of blood ... Inhibition of the renin-angiotensin-aldosterone system (RAAS) improves survival in ...
This animation focuses on the renin angiotensin aldosterone system (RAAS), a classic endocrine system that helps to regulate long-term blood pressure and extracellular volume in the body. Many aspects of ...

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★リンクテーブル★
リンク元アンジオテンシンII」「レニン-アンギオテンシン-アルドステロン系」「RAA」「レニン・アンジオテンシン・アルドステロン系」「RAAS
関連記事system」「angiotensin」「aldosterone」「renin

アンジオテンシンII」

  [★]

angiotensin II, AT II
renin-angiotensin-aldosterone system輸出細動脈#調節


標的組織

受容体 (PPC.348,SP.612)

  • AT1受容体:血管、副腎皮質、脳室周囲器官 (SP.612)
血管収縮、アルドステロン分泌(副腎皮質)、交感神経刺激作用、心肥大・血管肥厚
  • AT2受容体:脳その他の臓器に存在し、NOの産生を介して血管を弛緩させるなどAT1受容体の機能に拮抗 (SP.612)
NO遊離(血管拡張)、アポトーシス

作用

  • Na+再吸収を促進→血漿量↑→血圧↑



レニン-アンギオテンシン-アルドステロン系」

  [★]

renin-angiotensin-aldosterone system RAA
レニン-アルドステロン系 renin-aldosterone system
アンギオテンシノゲンアンギオテンシンIアンギオテンシンIIアンギオテンシンIIIレニン-アンギオテンシン系



RAA」

  [★]


レニン・アンジオテンシン・アルドステロン系」

  [★]

renin-angiotensin-aldosterone system
レニン・アンジオテンシン系 renin-angiotensin system


RAAS」

  [★] レニン-アンギオテンシン-アルドステロン系 renin-angiotensin-aldosterone system


system」

  [★]

  • n.
methodseriesstrain


WordNet   license wordnet

「(physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"」

WordNet   license wordnet

「a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going"」
scheme

WordNet   license wordnet

「a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender"」
system of rules

WordNet   license wordnet

「a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"」

WordNet   license wordnet

「a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"」

WordNet   license wordnet

「the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"」

PrepTutorEJDIC   license prepejdic

「〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身」

WordNet   license wordnet

「instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"」


angiotensin」

  [★] アンジオテンシン

WordNet   license wordnet

「any of several vasoconstrictor substances (trade name Hypertensin) that cause narrowing of blood vessels」
angiotonin, Hypertensin


aldosterone」

  [★] アルドステロン

WordNet   license wordnet

「a corticosteroid hormone that is secreted by the cortex of the adrenal gland; regulates salt (sodium and potassium) and water balance」


renin」

  [★] レニン

WordNet   license wordnet

「a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure」




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