protein degradation

出典: meddic

proteolysesproteolysisproteolyticproteolytic degradationproteolyze

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/05 06:12:09」(JST)

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  • Elongated oligonucleotide-linked immunosorbent assay for sensitive detection of a biomarker in a microwell plate-based platform.
  • Han KC, Yang EG, Ahn DR.SourceCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea. Electronic address:
  • Biosensors & bioelectronics.Biosens Bioelectron.2013 Dec 15;50:421-4. doi: 10.1016/j.bios.2013.07.012. Epub 2013 Jul 17.
  • The immunoassay is a representative method for detecting disease biomarkers and pathogenic biological agents. While the conventional enzyme-linked immunosorbent assay (ELISA) has been routinely used for the analysis of biological samples, methods with higher sensitivity are still in demand because t
  • PMID 23896521
  • Effect of protein oxidation on the in vitro digestibility of soy protein isolate.
  • Chen N, Zhao M, Sun W.SourceCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, China.
  • Food chemistry.Food Chem.2013 Dec 1;141(3):3224-9. doi: 10.1016/j.foodchem.2013.05.113. Epub 2013 Jun 4.
  • Soy protein isolate (SPI) was modified by 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH) oxidation pretreatment, and the in vitro digestibility of oxidised SPI was investigated. Results indicated that oxidation induced amino acid modification. The amount of most amino acids decreased, accompa
  • PMID 23871081
  • Effect of citric acid deamidation on in vitro digestibility and antioxidant properties of wheat gluten.
  • Qiu C, Sun W, Cui C, Zhao M.SourceCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, China.
  • Food chemistry.Food Chem.2013 Dec 1;141(3):2772-8. doi: 10.1016/j.foodchem.2013.05.072. Epub 2013 May 24.
  • The effects of citric acid deamidation on the physiochemical properties of wheat gluten were investigated. In vitro digestion was carried out to determine changes of molecular weight distribution, amino acids composition and antioxidant efficacy of wheat gluten hydrolysates. Results indicated that c
  • PMID 23871023


  • Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein.
  • Masaki So,Yoshimoto Rei,Kaida Daisuke,Hata Asuka,Satoh Takayuki,Ohno Mutsuhito,Kataoka Naoyuki
  • International journal of molecular sciences 16(2), 3705-3721, 2015-02-09
  • … Here, we report protein interaction between human Debranching enzyme 1 (hDbr1) and several factors found in the Intron Large (IL) complex, which is an intermediate complex of the intron degradation pathway. … The hDbr1 protein specifically interacts with xeroderma pigmentosum, complementeation group A (XPA)-binding protein 2 (Xab2). …
  • NAID 120005555507
  • An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease
  • Kizuka Yasuhiko,Kitazume Shinobu,Fujinawa Reiko,Saito Takashi,Iwata Nobuhisa,Saido Takaomi C.,Nakano Miyako,Yamaguchi Yoshiki,Hashimoto Yasuhiro,Staufenbiel Matthias,Hatsuta Hiroyuki,Murayama Shigeo,Manya Hiroshi,Endo Tamao,Taniguchi Naoyuki
  • EMBO Molecular Medicine 7(2), 175-189, 2015-02-01
  • … The β-site amyloid precursor protein cleaving enzyme-1 (BACE1), an essential protease for the generation of amyloid-β (Aβ) peptide, is a major drug target for Alzheimer's disease (AD). … Analysis of knockout mice lacking the biosynthetic enzyme for bisecting GlcNAc, GnT-III (Mgat3), revealed that cleavage of Aβ-precursor protein (APP) by BACE1 is reduced in these mice, resulting in a decrease in Aβ plaques and improved cognitive function. …
  • NAID 120005549837
  • 大豆たんぱく質の酵素分解に及ぼすグアーガムの影響
  • 吉村 美紀,原口 朋子,加藤 陽二 [他]
  • 兵庫県立大学環境人間学部研究報告 (17), 51-55, 2015
  • NAID 40020411525


The intracellular degradation of protein may be achieved in two ways - proteolysis in lysosome, or a ubiquitin-dependent process which targets unwanted proteins to proteasome. The autophagy-lysosomal pathway is normally a non-selective ...
Individual cellular proteins turn over (are degraded and re-synthesized) at different rates. For example .... Selective protein degradation occurs in the proteasome, a large protein complex located in the nucleus and cytosol of eukaryotic cells.


Ubiquitin + HS-E1 +ATP----> Ubiquitin—C , the proteasome and protein degradation protein degradationroles of intracellular protein-degradation Protein degradation systems in viral Figure 1 : Boosting protein degradation to




protein degradationproteolysesproteolyticproteolytic degradationproteolyze

WordNet   license wordnet

「the hydrolysis of proteins into peptides and amino acids by cleavage of their peptide bonds」



  • タンパク分解性の、タンパク分解の、タンパク質分解の
protein degradationproteolysesproteolysisproteolytic degradationproteolyticallyproteolyze

WordNet   license wordnet

「of or relating to proteolysis」



proteolysisprotein degradationproteolytic degradationproteolysesproteolytic



proteolysisproteolysesprotein degradationproteolyzeproteolytic




protein degradationproteolysisproteolyticproteolytic degradationproteolyze



  • n.

WordNet   license wordnet

「changing to a lower state (a less respected state)」

PrepTutorEJDIC   license prepejdic

「(地位の)格下げ / (品位などの)下落」


  [★] 蛋白質

WordNet   license wordnet

「any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"」

PrepTutorEJDIC   license prepejdic