WordNet

stated explicitly or in detail; "needed a specific amount"
a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria"
(sometimes followed by `to'
being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements"
relating to or distinguishing or constituting a taxonomic species; "specific characters"
wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
a fully differentiated structural and functional unit in an animal that is specialized for some particular function
a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
a periodical that is published by a special interest group; "the organ of the communist party"
an antibody acting against tissues of the organism that produces it

PrepTutorEJDIC

《名詞の前にのみ用いて》『特定の』,一定の・『明確な』,明白な・(そのものに)『特有の』,独特の《+『to』+『名』》・〈C〉(…の)特効薬《+『for』+『名』》・《複数形で》明細,細部(details)
『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関

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Klocke K1, Sakaguchi S2, Holmdahl R1, Wing K3.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2016 Apr 26;113(17):E2383-92. doi: 10.1073/pnas.1603892113. Epub 2016 Apr 11.
Cytotoxic T lymphocyte antigen-4 (CTLA-4) is essential for immunological (self-) tolerance, but due to the early fatality of CTLA-4 KO mice, its specific function in central and peripheral tolerance and in different systemic diseases remains to be determined. Here, we further examined the role of CT
PMID 27071130

Positivity rates of antithyroid antibody, antinuclear antibody and thyroid peroxidase antibody in different types of vitiligo.

Lim HK1, Bae MI1, Jeong KH1, Shin MK1, Lee MH1.
Clinical and experimental dermatology.Clin Exp Dermatol.2016 Apr;41(3):242-7. doi: 10.1111/ced.12771. Epub 2015 Oct 9.
BACKGROUND: Vitiligo is associated with various autoimmune disorders, and organ-specific autoantibodies are frequently found in patients with this disorder. Vitiligo is classically divided into segmental vitiligo (SV) and nonsegmental vitiligo (NSV), and it is believed that the pathogenesis differs
PMID 26452586

Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men.

Panimolle F1, Tiberti C2, Granato S2, Semeraro A2, Gianfrilli D2, Anzuini A2, Lenzi A2, Radicioni A2.
Endocrine.Endocrine.2016 Apr;52(1):157-64. doi: 10.1007/s12020-015-0613-y. Epub 2015 May 3.
The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter's syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison's disease (AD), Hashimoto thyroiditis (HT), and autoimmune chronic atrophic
PMID 25935328

千田奈津子,小林一郎
日本臨床免疫学会会誌 38(3), 142-149, 2015
中枢性免疫寛容の異常によって生じるAutoimmune polyendocrinopathy, candidiasis, ectodermal dystrophy（APECED）と末梢性免疫寛容の異常によって生じるImmunedysregulation, polyendocrinopathy, enteropathy, X-linked syndrome（IPEX症候群）は共に多彩な自己免疫疾 …
NAID 130005089219

川﨑英二,江口勝美
Biomedical Research on Trace Elements 21(1), 13-16, 2010
… Type 1 diabetes is an organ-specific autoimmune disease characterized by T-cell mediated destruction of pancreatic β-cells and the circulating autoantibodies to multiple islet autoantigens. … These results indicate that variant residue at aa325 is a key determinant of humoral autoreactivity to ZnT8, SLC30A8 genotype is an important determinant of autoantibody specificity, and ZnT8 auoantibodies are an additional useful marker for Japanese type 1 diabetes. …
NAID 130004456891

Pelletier-Morel Lorraine,Fabien Nicole,Mouhoub Yamina,Boitard Christian,Larger Etienne
Internal Medicine 47(21), 1911-1915, 2008
… In this context of two associated organ-specific autoimmune diseases we searched for autoantibodies directed to parathyroid tissue and to calcium-sensing receptor. … Anti-parathyroid autoantibodies were detected by indirect immunofluorescence on parathyroid adenomas, and autoantibody against a peptide of the extracellular domain of the calcium-sensing receptor were detected by immunoblotting. …
NAID 130000079590