muscarinic agonist

出典: meddic

muscarinicmuscarinic cholinergic agonistmuscarinic receptor agonist

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/04/30 22:56:12」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.


  • Scopolamine and amphetamine produce similar decision-making deficits on a rat gambling task via independent pathways.
  • Silveira MM1, Malcolm E2, Shoaib M2, Winstanley CA3.
  • Behavioural brain research.Behav Brain Res.2015 Mar 15;281:86-95. doi: 10.1016/j.bbr.2014.12.029. Epub 2014 Dec 18.
  • Disorders characterized by disturbed cholinergic signaling, such as schizophrenia, exhibit impaired performance on measures of real-world cost/benefit decision-making. Whether the cholinergic system contributes to the choice deficits observed is currently unknown. We therefore determined the effects
  • PMID 25529186
  • In vitro recordings of human neocortical oscillations.
  • Florez CM1, McGinn RJ1, Lukankin V1, Marwa I1, Sugumar S1, Dian J1, Hazrati LN2, Carlen PL3, Zhang L4, Valiante TA5.
  • Cerebral cortex (New York, N.Y. : 1991).Cereb Cortex.2015 Mar;25(3):578-97. doi: 10.1093/cercor/bht235. Epub 2013 Sep 17.
  • Electrophysiological oscillations are thought to create temporal windows of communication between brain regions. We show here that human cortical slices maintained in vitro can generate oscillations similar to those observed in vivo. We have characterized these oscillations using local field potenti
  • PMID 24046077
  • Solabegron : a potential future addition to the β-3 adrenoceptor agonist armamentarium for the management of overactive bladder.
  • Ellsworth P1, Fantasia J.
  • Expert opinion on investigational drugs.Expert Opin Investig Drugs.2015 Mar;24(3):413-419. Epub 2015 Jan 5.
  • Introduction: Overactive bladder (OAB) affects many women and men worldwide and has a significant adverse effect on a person's quality of life. Historically, behavioral therapy and anti-muscarinic agents have been the primary therapies used in the management of OAB. However, persistence with anti-mu
  • PMID 25557359


  • Selective M_3 Muscarinic Receptor Antagonist Inhibits Small-Cell Lung Carcinoma Growth in a Mouse Orthotopic Xenograft Model
  • AMI Nozomi,KOGA Kazumi,FUSHIKI Hiroshi,UENO Yoko,OGINO Yoshio,OHTA Hisashi
  • Journal of pharmacological sciences 116(1), 81-88, 2011-05-20
  • … In small cell lung carcinoma (SCLC), acetylcholine (ACh) is synthesized and secreted, and it acts as an autocrine growth factor through activation of its receptors, muscarinic receptor (mAChR) and nicotinic receptor (nAChR). … We used a highly selective M3 muscarinic antagonist, N-(2-[3-([3R]-1-(cyclohexylmethyl)-3-piperidinyl]methylamino)-3-oxopropyl]amino-2-oxoethyl)-3,3,3-triphenyl-propioamide (J-115311). …
  • NAID 10029894058
  • Decreased Motility of the Lower Esophageal Sphincter in a Rat Model of Gastroesophageal Reflux Disease May Be Mediated by Reductions of Serotonin and Acetylcholine Signaling
  • Saegusa Yayoi,Takeda Hiroshi,Muto Shuichi,Oridate Nobuhiko,Nakagawa Koji,Sadakane Chiharu,Nahata Miwa,Harada Yumi,Iizuka Mizuki,Hattori Tomohisa,Asaka Masahiro
  • Biological & Pharmaceutical Bulletin 34(5), 704-711, 2011
  • … The in vivo motility proximal to LES (% motility index) in conscious rats was decreased by atropine treatment and increased by cisapride (5-HT4 receptor agonist) treatment. … The mRNA expressions of 5-HT4 and muscarinic acetylcholine 3 receptors were significantly reduced in esophageal LES strips of GERD rats compared with sham-operated rats. …
  • NAID 130000657784


Overview A muscarinic receptor agonist is an agent that enhances the activity of the muscarinic acetylcholine receptor. The muscarinic receptor has different subtypes, labelled M1-M5, allowing for further differentiation. In the form of pilocarpine ...
Cevimeline (AF102B) (Evoxac ) is a muscarinic agonist that is an Food and Drug Administration (FDA)-approved drug and used for the management of dry mouth in Sjögren's syndrome. Muscarinic versus nicotinic activity Edit [6] ...



リンク元ムスカリン作用薬」「ムスカリン受容体刺激薬」「ムスカリン作動薬」「ムスカリンアゴニスト」「muscarinic cholinergic agonist



muscarinic agonistmuscarinic



muscarinic agonistmuscarinic receptor agonistmuscarinic cholinergic agonist



muscarinic agonist, muscarinic cholinergic agonist



muscarinic agonist

muscarinic cholinergic agonist」


muscarinic agonistmuscarinic receptor agonist


  [★] 作動薬

WordNet   license wordnet

「(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction」

WordNet   license wordnet

「a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"」

WordNet   license wordnet

「someone involved in a contest or battle (as in an agon)」



  • adj.
  • ムスカリン性の、ムスカリンの
  • n.
cholinergiccholinergic agentcholinergic drugcholinomimeticmuscarinemuscarinic agentmuscarinic agonist