multisystem atrophy

出典: meddic

多系統萎縮症 MSA multiple system atrophy

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/10/09 23:46:04」(JST)

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  • Lack of effect of sacral nerve stimulation for incontinence in patients with systemic sclerosis.
  • Butt SK1, Alam A1, Cohen R1, Krogh K2, Buntzen S3, Emmanuel A1.
  • Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.Colorectal Dis.2015 Oct;17(10):903-907. doi: 10.1111/codi.12969.
  • AIM: Systemic sclerosis (SSc) is a multisystem disorder of unknown aetiology leading to the deposition of excessive connective tissue in the skin, blood vessels and internal organs. Gastrointestinal involvement occurs in 90% of cases and the prevalence of faecal incontinence (FI) is 38%. This study
  • PMID 25850948
  • White matter differences between multiple system atrophy (parkinsonian type) and Parkinson's disease: A diffusion tensor image study.
  • Ji L1, Wang Y2, Zhu D1, Liu W3, Shi J4.
  • Neuroscience.Neuroscience.2015 Oct 1;305:109-16. doi: 10.1016/j.neuroscience.2015.07.060. Epub 2015 Jul 26.
  • The clinical differential diagnosis between the Parkinson variant of multiple system atrophy (MSA-P) and Parkinson's disease (PD) is difficult in early stages. To identify objective markers for differential diagnosis, we combined the novel tract-based spatial statistics (TBSS) and region of interest
  • PMID 26215920
  • Failure of Neuroprotection Despite Microglial Suppression by Delayed-Start Myeloperoxidase Inhibition in a Model of Advanced Multiple System Atrophy: Clinical Implications.
  • Kaindlstorfer C1, Sommer P, Georgievska B, Mather RJ, Kugler AR, Poewe W, Wenning GK, Stefanova N.
  • Neurotoxicity research.Neurotox Res.2015 Oct;28(3):185-94. doi: 10.1007/s12640-015-9547-7. Epub 2015 Jul 21.
  • Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disease. Post-mortem hallmarks of MSA neuropathology include oligodendroglial α-synuclein (αSYN) inclusions, striatonigral degeneration, olivopontocerebellar atrophy, and increased microglial activation that accompanies the w
  • PMID 26194617


  • シンポジウム23‐2 医師不足時代の神経内科医療の在り方‐都市と田舎での医療デバイド 青森県における神経内科医療事情について
  • 冨山 誠彦
  • 臨床神経学 50(11), 1063-1065, 2010
  • … The percentage of people having medical care certificate for six specified neurological disorders (multiple sclerosis, myasthenia gravis, amyotrophic lateral sclerosis, spinocerebellar degeneration, Parkinson disease and related disorders, and multisystem atrophy) in Aomori was comparable to the nationwide average. …
  • NAID 130004504618
  • An Autopsy Case of Myotonic Dystrophy. With Special Reference to Tongue Muscles.:With Special Reference to Tongue Muscles
  • 熊本 裕行,大家 清
  • 日本口腔科学会雑誌 41(1), 37-41, 1992
  • … Myotonic dystrophy is a hereditary multisystem disease characterized by myotonia and muscle atrophy. … An autopsied tongue macroscopically showed atrophy in the anterior region with yellowish cut surfaces. … Histological examination revealed severe atrophy of tongue muscles with nuclear and myofibrillar changes and replacement by fat cells. …
  • NAID 130004114192
  • Bilateral vocal cord abductor impairment in a patient with spino-cerebellar degeneration with a detailed report on relatively acute laryngeal symptoms.
  • 小山内 龍一,林田 哲郎,磯崎 英治,室伏 利久,水野 正浩,山根 雅昭,田邊 等
  • 耳鼻咽喉科臨床 83(11), 1679-1686, 1990
  • A 57-year-old male patient with spino-cerebellar degeneration and slowly progressive cerebellar ataxia, pyramidal tract signs, extrapyramidal tract signs and autonomic failure of 9 years duration fina …
  • NAID 130001811444


Multisystem atrophy (MSA) is a group of rare, multisystem degenerative diseases that have several clinical features of Parkinson's disease and are sometimes referred to as the Parkinsonism-plus syndromes.
multiple-system atrophy An uncommon (5/105) neurodegenerative disorder (”tauopathy”) with incomplete penetrance, characterised by: (1) Parkinsonism, ... In Alzheimer's, as well as in progressive supranuclear palsy and multisystem atrophy ...


 Cerebellar Signs and Multisystem AtrophyMultiple System AtrophyDysautonomia, Multisystem Atrophy and Multisystem atrophy (MSA) | Image Multisystem atrophy (MSA) | Image Multisystem atrophy (MSA) | Image

先読みmultiple system atrophy

multiple system atrophy」

  [★] 多系統萎縮症 MSA



multiple system atrophy, MSA, multisystem atrophy



  • 3疾患は進行すると共通した病理像を呈する。
  • 脳幹のグリアや神経細胞の細胞質内に特徴的な封入体(glial cytoplasmic inclusion, GCI、neuronal cytoplasmic inclusion, NCI)が存在する





  • n.

WordNet   license wordnet

「a decrease in size of an organ caused by disease or disuse」
wasting, wasting away

WordNet   license wordnet

「undergo atrophy; "Muscles that are not used will atrophy"」

WordNet   license wordnet

「any weakening or degeneration (especially through lack of use)」

PrepTutorEJDIC   license prepejdic

「(栄養不良などによる)萎縮(いしゅく) / (一般的に)衰退,退化 / 萎縮する,衰退する / …'を'萎縮させる,衰退させる」