WordNet

increase in price or value; "the news caused a general advance on the stock market" (同)rise
an amount paid before it is earned (同)cash advance
rise in rate or price; "The stock market gained 24 points today" (同)gain
pay in advance; "Can you advance me some money?"
situated ahead or going before; "an advance party"; "at that time the most advanced outpost was still east of the Rockies" (同)advanced, in advance
being ahead of time or need; "gave advance warning"; "was beforehand with her report" (同)beforehand
cause to move forward; "Can you move the car seat forward?" (同)bring forward
move forward, also in the metaphorical sense; "Time marches on" (同)progress, pass_on, move on, march on, go_on
move forward; "we have to advance clocks and watches when we travel eastward" (同)set ahead
bring forward for consideration or acceptance; "advance an argument" (同)throw out
develop further; "We are advancing technology every day"
farther along in physical or mental development; "the childs skeletal age was classified as `advanced"; "children in the advanced classes in elementary school read far above grade average"
ahead of the times; "the advanced teaching methods"; "had advanced views on the subject"; "a forward-looking corporation"; "is British industry innovative enough?" (同)forward-looking, innovative, modern
far along in time; "a man of advanced age"; "advanced in years"; "a ripe old age"; "the ripe age of 90" (同)ripe
ahead in development; complex or intricate; "advanced technology"; "a sophisticated electronic control system" (同)sophisticated
(of societies) highly developed especially in technology or industry; "advanced societies"; "an advanced country technologically"
at a higher level in training or knowledge or skill; "an advanced degree"; "an advanced text in physics"; "special seminars for small groups of advanced students at the University"
comparatively late in a course of development; "the illness had reached an advanced stage"; "an advanced state of exhaustion"
relating to or applicable to or concerned with the administration of a city or town or district rather than a larger area; "local taxes"; "local authorities"
public transport consisting of a bus or train that stops at all stations or stops; "the local seemed to take forever to get to New York"
affecting only a restricted part or area of the body; "local anesthesia"
of or belonging to or characteristic of a particular locality or neighborhood; "local customs"; "local schools"; "the local citizens"; "a local point of view"; "local outbreaks of flu"; "a local bus line"
type genus of the family Cancridae (同)genus Cancer
the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 (同)Cancer the Crab, Crab
(astrology) a person who is born while the sun is in Cancer (同)Crab
a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
by a particular locality; "it was locally decided"
to a restricted area of the body; "apply this medicine topically" (同)topically

PrepTutorEJDIC

…'を'『前進させる』,前に出す / 〈事〉'を'『進める』,促進する / (ある階級・地位などに)〈人〉'を'昇進させる《+『名』〈人〉+『to』+『名』》 / 《『advance』+『名』〈人〉+『名』〈金〉=『advance』+『名』〈金〉+『to』+『名』〈人〉》〈人〉‘に'〈金〉'を'前払いする,融資する / 〈時間・期日〉'を'早める;〈時計〉‘の'時間を早める / (…に向かって)『前進する』,進む《+『on』(『upon, toward』)+『名』》 / (…に)昇進する《+『to』(『in』)+『名』》 / 〈事が〉進歩する,はかどる / 〈時が〉進む / 〈値段・価値が〉上がる / 〈U〉〈C〉『進むこと』,前進 / 〈U〉(…の)流れ,進行《+『of』+『名』》 / 〈U〉〈C〉(…の)進歩,発達《+『of』+『名』》 / 〈U〉〈C〉(…への)昇進,出世《+『to』+『名』》 / 〈C〉(…の)前払い,前払い金《+『on』+『名』》 / 《複数形で》(人に)言い寄ること,取り入ること《+『to』+『名』》 / 前進している / 前もっての
進出した,前進した / 進歩した / 上級の,高等の / (時が)進んだ,進行した
『一地方の』,ある土地の,(特に)自分の住んでいる土地の;地方に特有な / (全体からみて)『部分的な』,局部の,狭い部分の / 《米》各駅停車の / 《話》《しばしば複数形で》その土地に住んでいる人々 / 《米話》(新聞の)地方記事 / 《話》(各駅停車の)列車,電車,バス / 《米》(労働組合などの)支部
低カロリーの
地方的に,局部的に;近くに

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1. 限局進行性および切除可能境界膵外分泌癌に対する初回化学療法および放射線治療 initial chemotherapy and radiation for nonmetastatic locally advanced unresectable borderline resectable and potentially resectable exocrine pancreatic cancer
2. 進行膵外分泌癌に対する支持療法 supportive care of the patient with advanced exocrine pancreatic cancer
3. 悪性膵胆管閉塞に対する内視鏡下ステント留置術 endoscopic stenting for malignant pancreaticobiliary obstruction
4. 成人における胃流出路閉塞 gastric outlet obstruction in adults
5. 治療を目的とした超音波内視鏡 therapeutic endoscopic ultrasound

English Journal

Posterior 'superior mesenteric artery first' approach for resection of locally advanced pancreatic cancer.

Rose JB1, Rocha F, Alseidi A, Helton S.
Annals of surgical oncology.Ann Surg Oncol.2014 Jun;21(6):1927-8. doi: 10.1245/s10434-013-3431-6. Epub 2013 Dec 27.
BACKGROUND: En bloc resection of the superior mesenteric vein (SMV), portal vein (PV), and/or splenic vein (SV) with concomitant venous reconstruction is required in 11-65 % of cases of locally advanced pancreatic cancer.1 Early retropancreatic dissection of the superior mesenteric artery (SMA) fro
PMID 24370905

Management options in locally advanced pancreatic cancer.

Mian OY1, Ram AN, Tuli R, Herman JM.
Current oncology reports.Curr Oncol Rep.2014 Jun;16(6):388. doi: 10.1007/s11912-014-0388-y.
Pancreatic ductal adenocarcinoma is a highly lethal cancer that is rarely curable at the time of presentation. Unfortunately, most patients are diagnosed with either metastatic or locally advanced disease, which is not amenable to surgery owing to the high likelihood of incomplete resection. Given t
PMID 24740136

Phase 1 pharmacogenetic and pharmacodynamic study of sorafenib with concurrent radiation therapy and gemcitabine in locally advanced unresectable pancreatic cancer.

Chiorean EG1, Schneider BP2, Akisik FM3, Perkins SM4, Anderson S5, Johnson CS4, DeWitt J5, Helft P2, Clark R2, Johnston EL2, Spittler AJ2, Deluca J6, Bu G3, Shahda S2, Loehrer PJ2, Sandrasegaran K3, Cardenes HR7.
International journal of radiation oncology, biology, physics.Int J Radiat Oncol Biol Phys.2014 Jun 1;89(2):284-91. doi: 10.1016/j.ijrobp.2014.02.024. Epub 2014 Apr 11.
PURPOSE: To define the safety, efficacy, and pharmacogenetic and pharmacodynamic effects of sorafenib with gemcitabine-based chemoradiotherapy (CRT) in locally advanced pancreatic cancer.METHODS AND MATERIALS: Patients received gemcitabine 1000 mg/m(2) intravenously weekly × 3 every 4 weeks per
PMID 24726286

Japanese Journal

切除不能局所進行膵がんに対する化学療法のエビデンス (特集新しい標準治療による膵がん治療成績の向上)

福冨晃
腫瘍内科 = Clinical oncology 15(6), 575-579, 2015-06
NAID 40020510958

Gemcitabine-induced CXCL8 expression counteracts its actions by inducing tumor neovascularization

Song Yao,Baba Tomohisa,Li Ying-Yi,Furukawa Kaoru,Tanabe Yamato,Matsugo Seiichi,Sasaki Soichiro,Mukaida Naofumi
Biochemical and Biophysical Research Communications 458(2), 341-346, 2015-03-02
… Patients with pancreatic ductal adenocarcinoma (PDAC) are frequently complicated with metastatic disease or locally advanced tumors, and consequently need chemotherapy. … The capacity of gemcitabine to generate reactive oxygen species (ROS) in human pancreatic cancer cells, prompted us to examine its effects on the expression of pro-inflammatory cytokines and chemokines. …
NAID 120005593940

13　臨床例―適応疾患と治療成績　5)膵臓・下部消化管

岡本雅彦,清原浩樹,岡野奈緒子
RADIOISOTOPES 64(6), 432-437, 2015
消化器に発生したがんは，消化管の耐容線量の低さから従来根治的な放射線治療の対象にはならなかった。しかし粒子線の良好な空間的線量分布により，消化管に原発したがんは依然として根治的な治療は難しいものの，消化管に囲まれるような臓器や領域の腫瘍へ治療の適応が広がっている。膵癌では切除可能例の術前照射，局所進行切除不能膵癌で，陽子線，重粒子(炭素イオン)線の有用性が報告されている。また直腸癌術後の再発病変に …
NAID 130005083507