出典: meddic


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「a soft silver-white univalent element of the alkali metal group; the lightest metal known; occurs in several minerals」
Li, atomic number 3

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/04/04 06:21:18」(JST)

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  • Characterization of conducting cellulose acetate based polymer electrolytes doped with "green" ionic mixture.
  • Ramesh S, Shanti R, Morris E.SourceCentre for Ionics University of Malaya, Department of Physics, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address:
  • Carbohydrate polymers.Carbohydr Polym.2013 Jan 2;91(1):14-21. doi: 10.1016/j.carbpol.2012.07.061. Epub 2012 Jul 31.
  • Polymer electrolytes were developed by solution casting technique utilizing the materials of cellulose acetate (CA), lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) and deep eutectic solvent (DES). The DES is synthesized from the mixture of choline chloride and urea of 1:2 ratios. The increasing
  • PMID 23044100
  • Differential responses to distinct psychotropic agents of selectively bred dominant and submissive animals.
  • Nesher E, Gross M, Lisson S, Tikhonov T, Yadid G, Pinhasov A.SourceDepartment of Molecular Biology, Ariel University Center, Ariel, Israel; Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel.
  • Behavioural brain research.Behav Brain Res.2013 Jan 1;236(1):225-35. doi: 10.1016/j.bbr.2012.08.040. Epub 2012 Sep 7.
  • Dominance and submissiveness are two opposite poles of behavior representing important functional elements in the development of social interactions. We previously demonstrated the inheritability of these traits by selective breeding based upon the dominant-submissive relationships (DSR) food compet
  • PMID 22982068
  • Application of visible light-based projection stereolithography for live cell-scaffold fabrication with designed architecture.
  • Lin H, Zhang D, Alexander PG, Yang G, Tan J, Cheng AW, Tuan RS.SourceCenter for Cellular and Molecular Engineering, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
  • Biomaterials.Biomaterials.2013 Jan;34(2):331-9. doi: 10.1016/j.biomaterials.2012.09.048. Epub 2012 Oct 22.
  • One-step scaffold fabrication with live cell incorporation is a highly desirable technology for tissue engineering and regeneration. Projection stereolithography (PSL) represents a promising method owing to its fine resolution, high fabrication speed and computer-aided design (CAD) capabilities. How
  • PMID 23092861


  • リチウムイオン二次電池の蓄電容量を高めるバインダー (特集 スマートフォン・タブレット端末を支えるテクノロジー)
  • Nitrergic, glutamatergic and gabaergic systems in lithium toxicity
  • Yamanturk-Celik Pinar,Unlucerci Yesim,Sevgi Serhan [他]
  • The Journal of toxicological sciences 37(5), 1017-1023, 2012-10
  • NAID 40019458209
  • リチウムイオン電池の開発動向について (特別小特集 関西の伝統文化と先端産業技術) -- (関西の先端産業技術)
  • 湯浅 浩次
  • 電子情報通信学会誌 95(10), 878-880, 2012-10
  • NAID 40019453872


16 Jun 2009 ... Music video by Nirvana performing Lithium. (C) 1992 Geffen Records.
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Lithium promotes longevity Lithium zeigen einen metallischen GlanzWhat is Lithium?Baare me Electron shell 003 lithium.pngElectron configurationsLithium Backpack ($47.36) HiCap Lithium Lithium Small lithium batteryLithium

拡張検索lithium-induced postural tremor



炭酸リチウム lithium carbonate


mood stabilizer

  • 5-HT、NEが受容体に結合
  • inositol monophosphatase, IMPase
  • wingless:ショウジョウバエ、ハネの発生に関する
  • Int-1:マウス乳癌
  • Wnt:相同遺伝子。分泌蛋白
  • 作用箇所
  • リン酸化GSK-3(不活型)-phosphatase(←Liにより抑制される)→GSK
  • GSK-3βはインスリン受容体の下流にも存在する。インスリンのGタンパク質を介したシグナルがPKA,PKC,Akt,p90RSKに伝わり、さらにGSK-3βを介して(p-ser9が介在)下流に伝わる
  • インスリンを経鼻投与すると海馬における学習や記憶力が向上するかもしれない


  • 急性リチウム中毒
  • 悪心、嘔吐、下痢、腎不全、神経筋機能不全、失行、振戦、混乱(confusion)、昏迷(deliriumてんかん発作 → may require dialysis
  • 低ナトリウム血症、NSAIDの投与 → 近位尿細管でのLi取り込み↑ → 血漿リチウム濃度上昇
  • (筋細胞)血漿リチウム濃度↑ → K+の細胞内の移動が妨げられる → 再分極の阻害 → 高カリウム血症 → 突然死
  • リチウム↑ → ADHTSHのシグナル伝達系下流に存在するadenylyl cyclaseを阻害 → 腎性尿崩症 and ( hypothyroidism and/or goiter)


  • 初期 1.5-2.5mEq/L 粗大振戦、失調、悪心、嘔吐、鎮静
  • 中度 2.5-3.5mEq/L 耳鳴り
  • 重度 3 -5 mEq/L 昏睡、血圧低下、腎障害



chronic interstitial nephritis, CIN
慢性尿細管間質性腎炎 chronic tubulointerstitial nephritis
  • 腎・泌尿器 081208I


  • hereditary renal diseases
  • exogenous toxins
  • metabolic toxins
  • autoimmune disorders
  • neoplastic disorders
  • miscellaneous disorders


  [★] リチウム


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lithium-induced postural tremor」

  [★] リチウム誘発性姿勢振戦

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