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English Journal

Insights into the structure-function relationship of Brugia malayi thymidylate kinase (BmTMK).

Doharey PK1, Singh SK2, Verma P1, Verma A1, Rathaur S3, Saxena JK4.
International journal of biological macromolecules.Int J Biol Macromol.2016 Jul;88:565-71. doi: 10.1016/j.ijbiomac.2016.04.004. Epub 2016 Apr 1.
Lymphatic filariasis is a debilitating disease caused by lymph dwelling nematodal parasites like Wuchereria bancrofti, Brugia malayi and Brugia timori. Thymidylate kinase of B. malayi is a key enzyme in the de novo and salvage pathways for thymidine 5'-triphosphate (dTTP) synthesis. Therefore, B. ma
PMID 27044348

Salt stress induces internalization of plasma membrane aquaporin into the vacuole in Arabidopsis thaliana.

Ueda M1, Tsutsumi N2, Fujimoto M3.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2016 Jun 10;474(4):742-6. doi: 10.1016/j.bbrc.2016.05.028. Epub 2016 May 6.
Salt stress is a major environmental stress for plants, causing hyperosmotic, ionic and drought-like stresses. Plasma membrane intrinsic protein 2;1 (PIP2;1), which forms a water channel that regulates water flux thorough the plasma membrane (PM), is constitutively trafficked between the PM and the
PMID 27163638

Imidazolium Ionic Liquids as Potential Anti-Candida Inhibitors: QSAR Modeling and Experimental Studies.

Hodyna D1, Kovalishyn V, Rogalsky S, Blagodatnyi V, Metelytsia L.
Current drug discovery technologies.Curr Drug Discov Technol.2016 May 10. [Epub ahead of print]
Quantitative structure-activity relationships (QSAR) of imidazolium ionic liquids (ILs) as inhibitors of C. albicans collection strains (IOA-109, KCTC 1940, ATCC 10231) have been studied. Predictive QSAR models were built using different descriptor sets for a set of 88 ionic liquids with known minim
PMID 27160290