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Yersiniosis is an infectious disease caused by a bacterium of the genus Yersinia. In the United States, most yersiniosis infections among humans are caused by Yersinia enterocolitica. The infection by Y. enterocolitica is also known as pseudotuberculosis.^[1] Yersiniosis is mentioned as a specific zoonotic disease to prevent outbreaks in European Council Directive 92/117/EEC.^[2]

Infection with Y. enterocolitica occurs most often in young children.^{[citation needed]} The infection is thought to be contracted through the consumption of undercooked meat products, unpasteurized milk, or water contaminated by the bacteria. It has been also sometimes associated with handling raw chitterlings.^[3]

Another bacterium of the same genius, Yersinia pestis, is the cause of Plague.

Symptoms

Infection with Y. enterocolitica can cause a variety of symptoms depending on the age of the person infected, therefore it's often referred to as "monkey of diseases". Common symptoms in children are fever, abdominal pain, and diarrhea, which is often bloody. Symptoms typically develop 4 to 7 days after exposure and may last 1 to 3 weeks or longer. In older children and adults, right-sided abdominal pain and fever may be the predominant symptoms, and may be confused with appendicitis. In a small proportion of cases, complications such as skin rash, joint pains, ileitis, erythema nodosum, and sometimes septicemia, acute arthritis^[1] or the spread of bacteria to the bloodstream (bacteremia) can occur.

Treatment

Treatment for gastroenteritis due to Y. enterocolitica is not needed in the majority of cases. Severe infections with systemic involvemenet (sepsis and bacteremia) often requires aggressive antibiotic therapy; the drugs of choice are doxycycline and an aminoglycoside. Alternatives include cefotaxime, co-trimoxazole and fluoroquinolones such as ciprofloxacin.^[4]^[5]

References

^ ^a ^b "Yersiniosis". Medical Dictionary. Retrieved 2013-01-28.
^ European Council Directive 92/117/EEC
^ Jones TF (August 2003). "From pig to pacifier: chitterling-associated yersiniosis outbreak among black infants". Emerging Infectious Diseases 9 (8): 1007–9. doi:10.3201/eid0908.030103. PMC 3020614. PMID 12967503.
^ Torok E. Oxford MHandbook of Infect Dis and Microbiol, 2009
^ Collins FM (1996). Pasteurella, and Francisella. In: Barron's Medical Microbiology (Barron S et al., eds.) (4th ed.). Univ of Texas Medical Branch. ISBN 0-9631172-1-1. (via NCBI Bookshelf).

UpToDate Contents

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1. エルシニア感染症の臨床症状および診断 clinical manifestations and diagnosis of yersinia infections
2. 腸炎エルシニアおよび偽結核菌感染症の治療および予防 treatment and prevention of yersinia enterocolitica and yersinia pseudotuberculosis infection
3. エルシニア症の疫学 epidemiology of yersiniosis
4. エルシニア感染の微生物学および病因 microbiology and pathogenesis of yersinia infections
5. 菊池病 kikuchi disease

English Journal

A history of fish vaccination: Science-based disease prevention in aquaculture.

Gudding R, Van Muiswinkel WB.SourceNorwegian Veterinary Institute, P.O. Box 750, 0106 Oslo, Norway. Electronic address: roar.gudding@vetinst.no.
Fish & shellfish immunology.Fish Shellfish Immunol.2013 Dec;35(6):1683-8. doi: 10.1016/j.fsi.2013.09.031. Epub 2013 Oct 5.
Disease prevention and control are crucial in order to maintain a sustainable aquaculture, both economically and environmentally. Prophylactic measures based on stimulation of the immune system of the fish have been an effective measure for achieving this goal. Immunoprophylaxis has become an import
PMID 24099805

Comparison of Cytokine Immune Responses to Brucella abortus and Yersinia enterocolitica Serotype O:9 Infections in BALB/c Mice.

Gu W, Wang X, Qiu H, Cui B, Zhao S, Zheng H, Xiao Y, Liang J, Duan R, Jing H.SourceNational Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, China.
Infection and immunity.Infect Immun.2013 Dec;81(12):4392-8. doi: 10.1128/IAI.00856-13. Epub 2013 Sep 16.
Brucella abortus and Yersinia enterocolitica serotype O:9 serologically cross-react in the immune response with the host; therefore, our aim was to compare the immune responses to these two pathogens. We selected typical B. abortus and Y. enterocolitica O:9 strains to study the cytokine immune respo
PMID 24042115

The Limitations of Pulsed-Field Gel Electrophoresis for Analysis of Yersinia enterocolitica Isolates.

Gilpin BJ, Robson B, Lin S, Hudson JA, Weaver L, Dufour M, Strydom H.SourceInstitute of Environmental Science and Research, Christchurch Science Centre, Christchurch, New Zealand.
Zoonoses and public health.Zoonoses Public Health.2013 Nov 15. doi: 10.1111/zph.12085. [Epub ahead of print]
This study describes the analysis of 432 isolates of Yersinia enterocolitica by pulsed-field gel electrophoresis (PFGE). PFGE had a high level of discrimination with biotype 1A isolates (Simpson's Diversity Index 0.997), but with the clinically important biotypes 2, 3 and 4, the discriminatory abili
PMID 24237638

Japanese Journal

Epidemiological Findings on Yersiniosis in Nonhuman Primates in Zoological Gardens in Japan

IWATA Taketoshi,HAYASHIDANI Hideki
Japan Agricultural Research Quarterly: JARQ 45(1), 83-90, 2011
… Yersiniosis, which is caused by pathogenic <I>Yersinia enterocolitica</I> … In this review, we will describe the epidemiology of yersiniosis in breeding nonhuman primates in Japan. …
NAID 130002147918

Spontaneous Yersiniosis Due to Yersinia pseudotuberculosis Serotype 7 in a Squirrel Monkey

Nakamura Shin-Ichi,Hayashidani Hideki,Iwata Taketoshi [他],TAKADA Mariko,UNE Yumi
Journal of Veterinary Medical Science 71(12), 1657-1659, 2009
A captive male Bolivian squirrel monkey (Saimiri boliviensis) of less than 1 year of age died following diarrhea and debilitation on the day of death. At necropsy, necrotizing enteritis accompanied wi …
NAID 130000149995

臨床報告開腹術によって病悩期間が短縮できた,Yersinia感染症に合致する腸間膜リンパ節炎の1例

遠藤秀彦,松田望,遠野千尋 [他]
臨床外科 63(3), 443-446, 2008-03
NAID 40015864597

Related Pictures

★リンクテーブル★

リンク元	「結節性紅斑」「エルシニア症」

「結節性紅斑」

Yersinia enterocolitica
Classification and external resources
ICD-10	A04.6, A04.6
ICD-9	008.44
DiseasesDB	14218
eMedicine	article/970186
MeSH	D015009

　　[★]

英: erythema nodosum EN
関

概念ツリー

皮下脂肪組織疾患

脂肪組織炎 panniculitis

疫学

成人女性に多い
上気道感染が先行することがある

病理

皮下脂肪隔壁への炎症細胞浸潤(septal panniculitis)がみられ、小葉は保たれる(小葉が冒されるのは硬結性紅斑)。通常は血管炎を伴わない。

http://dermatology.cdlib.org/144/drugs/erythemanodosum/3.jpg

症状

下腿伸側を中心、左右対称性、境界不明瞭な淡紅色の紅斑
大きさは1-10cm
わずかから盛り上がる硬結、熱覚、圧痛・自発痛、潰瘍は形成しない。

原因

細菌、真菌、ウイルスによる感染アレルギー

NDE.307

疾患	所見
細菌，真菌，ウイルスによる感染アレルギー	各種感染症の他症状
ベーチェット病	ほかの所見の存在（口腔内アフタ、眼ぶどう膜炎、外陰部潰瘍）、針反応
結核	ツ反、組織にて結核性肉芽腫、胸部Xp
サルコイドーシス	胸部XpにてBHL、眼ぶどう膜炎、血中Ca・ACE、リゾチームの高値、ツ反陰性化
薬疹	薬剤内服歴の調査
潰瘍性大腸炎，Crohn病	便潜血、消化管検査
骨髄異形成症候群	骨髄および末梢血の血球像の異型性、染色体異常
Hansen病	組織所見、レプロミン反応、神経学的所見

結節性紅斑と硬結性紅斑

NDE.305

	結節性紅斑	硬結性紅斑
圧痛	○	×
潰瘍	×	○
病理	皮下脂肪組織隔壁の炎症	小葉性脂肪織炎
病因	感染アレルギーベーチェット病結核サルコイドーシス薬疹潰瘍性大腸炎、クローン病骨髄異形成症候群ハンセン病	結核によるアレルギー(結核疹)