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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/12 15:37:32」(JST)

English Journal

Retraction. A Prospective Randomized Trial to Compare the Efficacy of Tramazoline and Cocaine for Nasal Vasoconstriction before Nasal Surgery.

Zhang JX1, Li ZY1, Zhao L1, Li G1, Cao GL1, Zhang CY1.
Drug research.Drug Res (Stuttg).2015 Dec;65(12):672. doi: 10.1055/s-0034-1387769. Epub 2014 Sep 4.
J.-X. Zhang, Z.-Y. Li, L. Zhao, G. Li, G.-L. Cao, C.-Y. Zhang are retracting their paper, entitled A Prospective Randomized Trial to Compare the Efficacy of Tramazoline and Cocaine for Nasal Vasoconstriction before Nasal Surgery [Drug Res 2014, epub ahead of print. September 4, 2014], claiming lack
PMID 25188610

Treatment of acute rhinitis with a nasal spray containing tramazoline and essential oils: a multicenter, uncontrolled, observational trial.

Katona G1, Sultész M1, Farkas Z1, Gyimesi A2, Hirschberg A2, Huszka J3, Radvánszky F3, Simon Á3, Fülöp G3, Láng J3, Ablonczy M4, Nirnberger G5, Holm C6.
Clinical and translational allergy.Clin Transl Allergy.2015 Nov 4;5:38. doi: 10.1186/s13601-015-0084-5. eCollection 2015.
BACKGROUND: In this observational trial, data were collected on the effectiveness and tolerability/safety of a nasal spray containing tramazoline and essential oils (trade name Rhinospray(®) Plus) used for symptomatic treatment of acute rhinitis due to common cold.METHODS: The trial was performed i
PMID 26539289

The effect of nasal tramazoline with dexamethasone in obstructive sleep apnoea patients.

Koutsourelakis I1, Minaritzoglou A, Zakynthinos G, Vagiakis E, Zakynthinos S.
The European respiratory journal.Eur Respir J.2013 Oct;42(4):1055-63. doi: 10.1183/09031936.00142312. Epub 2013 Feb 8.
Although there is a strong correlation between oral/oro-nasal breathing and apnoea/hypopnoea index in patients with obstructive sleep apnoea and normal nasal resistance at wakefulness, it remains unknown whether the pharmacological prevention of potential nasal obstruction during sleep could decreas
PMID 23397296

竹野幸夫,川本浩子,平田したう,福島典之,夜陣紘治
日本耳鼻咽喉科學會會報 101(7), 900-907, 1998-07-20
… In this prospective clinical study, we investigated the effect of the nasal decongestant tramazoline on nasal airway patency in 30 subjects with perennial nasal allergy to housedust mites and in six non-allergic volunteers who served as controls. …
NAID 10005598313

リンク元	「トラマゾリン」
拡張検索	「tramazoline hydrochloride」

Tramazoline
Systematic (IUPAC) name
	N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	1082-57-1
ATC code	R01AA09
PubChem	CID 5524
UNII	SLE31693IV
ChEMBL	CHEMBL32573
Chemical data
Formula	C13H17N3
Molar mass	215.294 g/mol
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