Biphasic effect of danazol on human vascular endothelial cell permeability and f-actin cytoskeleton dynamics.
Thomas GW, Rael LT, Bar-Or R, Mains CW, Slone DS, Boyd SR, Bar-Or D.SourceSwedish Medical Center, Trauma Research Laboratory, Englewood, CO, USA.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2012 Apr 21. [Epub ahead of print]
Breakdown of endothelial barrier function is a hallmark event across a variety of pathologies such as inflammation, cancer, and diabetes. It has also been appreciated that steroid hormones impart direct biological activity on endothelial cells at many levels. The purpose of this investigation was to
The Cell Adhesion Molecule Neuroplastin-65 Is a Novel Interaction Partner of γ-Aminobutyric Acid Type A Receptors.
Sarto-Jackson I, Milenkovic I, Smalla KH, Gundelfinger ED, Kaehne T, Herrera-Molina R, Thomas S, Kiebler MA, Sieghart W.SourceFrom the Center for Brain Research, Department of Biochemistry and Molecular Biology of the Nervous System, Medical University of Vienna, 1090 Vienna, Austria.
The Journal of biological chemistry.J Biol Chem.2012 Apr 20;287(17):14201-14. Epub 2012 Mar 2.
γ-Aminobutyric acid type A (GABA(A)) receptors are pentameric ligand-gated ion channels that mediate fast inhibition in the central nervous system. Depending on their subunit composition, these receptors exhibit distinct pharmacological properties and differ in their ability to interact with protei
… Pour a mixture of jel-foam, glycerin and 0.9% saline solution into the eustachian tube.Grade II: Grade I plus autophonia and tympanic membrane movement during Toynbee's or Valsalva's maneuver.Therapy·In addition to that proposed for Grade I, submembranous injection of dimethyl polysiloxan or aterocollagen into the nasopharyngeal tubal orifice.Grade III: Most severe case.Therapy·In addition to that proposed for Grade II, insertion of KOBAYASHI's eustachian tube pin into the tympanic orifice of the eustachian tube. …