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1. 新生児における赤血球輸血red blood cell transfusions in the newborn [show details]
… hemolytic transfusion reaction. In these cases, red cells that are negative for the antigen, against which the antibody is directed, are used. RBCs are used for replacement during surgery, RBC loss, and …
2. 乳児や小児への赤血球輸血：血液製剤の選択red blood cell transfusion in infants and children selection of blood products [show details]
… discussed in separate topic reviews: RBCs is the blood product of choice for replacement during surgery, red cell loss, and sporadic transfusion therapy. The hematocrit of the unit varies depending …
3. 術中に成人に行う成分輸血intraoperative transfusion of blood products in adults [show details]
… achieved. If RBC units have not been made available and the need is emergent, the transfusion service can provide "immediate release" blood without pretransfusion testing. Decisions to transfuse RBCs weigh …
4. 鎌状赤血球症における赤血球輸血red blood cell transfusion in sickle cell disease [show details]
… severely anemic and hypovolemic, RBC transfusion can be used if performed promptly (eg, within minutes); however, volume replacement should not be delayed while awaiting transfusion. Accelerated hemolysis …
5. 大量輸血massive blood transfusion [show details]
… Massive transfusion, historically defined as the replacement by transfusion of 10 units of red cells in 24 hours, is a response to massive and uncontrolled hemorrhage. With more rapid and effective therapy …

English Journal

The impact of pre-operative intravenous iron on quality of life after colorectal cancer surgery: outcomes from the intravenous iron in colorectal cancer-associated anaemia (IVICA) trial.

Keeler BD, Dickson EA, Simpson JA, Ng O, Padmanabhan H, Brookes MJ, Acheson AG, .
Anaesthesia. 2019 Jun;74(6)714-725.
Anaemia is associated with a reduction in quality of life, and is common in patients with colorectal cancer . We recently reported the findings of the intravenous iron in colorectal cancer-associated anaemia (IVICA) trial comparing haemoglobin levels and transfusion requirements following intravenou
PMID 30963552

High prevalence and poor linkage to care of transfusion-transmitted infections among blood donors in Dar-es-Salaam, Tanzania.

Mohamed Z, Kim JU, Magesa A, Kasubi M, Feldman SF, Chevaliez S, Mwakale P, Taylor-Robinson SD, Thursz MR, Shimakawa Y, Rwegasha J, Lemoine M.
Journal of viral hepatitis. 2019 Jun;26(6)750-756.
Blood transfusion is one of the most commonly relied upon therapies in sub-Saharan Africa. Existing safeguards recommended include systematic screening for transfusion-transmitted infections and restricted voluntary nonremunerated blood donor selection. We report the transfusion-transmitted infectio
PMID 30712273

Hemolytic reaction in the washed salvaged blood of a patient with paroxysmal nocturnal hemoglobinuria.

Kawamoto Y, Nishihara T, Watanabe A, Nakanishi K, Hamada T, Konishi A, Abe N, Kitamura S, Ikemune K, Toda Y, Yorozuya T.
BMC anesthesiology. 2019 May;19(1)83.
In patients with paroxysmal nocturnal hemoglobinuria (PNH), the membrane-attack complex (MAC) formed on red blood cells (RBCs) causes hemolysis due to the patient's own activated complement system by an infection, inflammation, or surgical stress. The efficacy of transfusion therapy for patients wit
PMID 31113379

Japanese Journal

胸骨圧迫によって下行大動脈に偽腔破裂を呈したと考えられた急性大動脈解離術後の1救命例

有馬大輔,梅木昭秀,山本哲史
日本心臓血管外科学会雑誌 48(1), 73-76, 2019
<p>心肺蘇生の際の胸骨圧迫に伴うさまざまな合併症が報告されている．大動脈解離術後に心肺停止に陥り胸骨圧迫による偽腔破裂を呈したと考えらえた症例を経験した．症例は79歳の女性．上行大動脈にentryを呈した急性大動脈解離（Stanford A型，DeBakey I型）の診断で，緊急手術を施行した．術後は特に問題なく経過し，POD 5にICUを退室するも，POD 6に痰詰まりから心肺停止 …
NAID 130007586929

心拍動下冠動脈バイパス術においてhydroxyethyl starch 70/0.5の代わりにhydroxyethyl starch 130/0.4を用いた輸液管理は，血液製剤投与必要性を低下させる

佐藤美浩,小林隆史,本郷修平,鈴木健二
岩手医学雑誌 70(1), 13-25, 2018
本邦にて2013年10月，第3世代人工膠質液hydroxyethyl starch (HES) 130/0.4が使用可能となり，これまでのHES 70/0.5と比較して，より高用量の投与が可能となった．今回我々はHES 70/0.5の代わりにHES 130/0.4を用いた輸液管理が，術中の血液製剤投与必要性に及ぼした影響を，後ろ向きに調査した．対象は2012年10月から2014年12月の間に，岩手 …
NAID 130007473016

外科周術期管理に関連した，血小板・血液凝固領域における最新の知見

小川覚,竹下秀祐
日本臨床麻酔学会誌 38(4), 519-530, 2018
<p>抗血栓療法の多様化に伴い，外科周術期における抗血栓薬の取り扱いに苦慮する機会は少なくない．高い抗血栓性を有した次世代drug-eluting stentの普及に伴い，ステント血栓症の発生数は低下傾向にあり，ステント挿入後に開始したP2Y12受容体遮断薬の中断時期は3〜6カ月間程度に短縮される傾向にある．ビタミンKや新鮮凍結血漿にかわり，ワルファリンの緊急拮抗にはプロトロンビン複合 …
NAID 130007468193