glycosylphosphatidylinositol-specific phospholipase C

グリコシルホスファチジルイノシトール特異的ホスホリパーゼC

関

glycosylphosphatidylinositol diacylglycerol-lyase、GPI-PLC

WordNet

1. stated explicitly or in detail; "needed a specific amount"
2. a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria"
3. (sometimes followed by `to'
4. being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements"
5. relating to or distinguishing or constituting a taxonomic species; "specific characters"
6. the 3rd letter of the Roman alphabet (同)c
7. (music) the keynote of the scale of C major
8. a general-purpose programing language closely associated with the UNIX operating system

PrepTutorEJDIC

1. 《名詞の前にのみ用いて》『特定の』,一定の・『明確な』,明白な・(そのものに)『特有の』,独特の《+『to』+『名』》・〈C〉(…の)特効薬《+『for』+『名』》・《複数形で》明細,細部(details)
2. carbonの化学記号
3. cesiumの化学記号
4. cadmiumの化学記号

UpToDate Contents

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• 1. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation
• 2. 血小板生物学 platelet biology
• 3. 発作性夜間血色素尿症の病因 pathogenesis of paroxysmal nocturnal hemoglobinuria
• 4. 先天性乳児ネフローゼ症候群 congenital and infantile nephrotic syndrome
• 5. 心筋における興奮収縮連関 excitation contraction coupling in myocardium

English Journal

• Determinants of GPI-PLC localisation to the flagellum and access to GPI-anchored substrates in trypanosomes.

• Sunter J1, Webb H, Carrington M.
• PLoS pathogens.PLoS Pathog.2013;9(8):e1003566. doi: 10.1371/journal.ppat.1003566. Epub 2013 Aug 22.
• In Trypanosoma brucei, glycosylphosphatidylinositol phospholipase C (GPI-PLC) is a virulence factor that releases variant surface glycoprotein (VSG) from dying cells. In live cells, GPI-PLC is localised to the plasma membrane where it is concentrated on the flagellar membrane, so activity or access
• PMID 23990786

• The receptor for urokinase regulates TLR2 mediated inflammatory responses in neutrophils.

• Liu G1, Yang Y, Yang S, Banerjee S, De Freitas A, Friggeri A, Davis KI, Abraham E.
• PloS one.PLoS One.2011;6(10):e25843. doi: 10.1371/journal.pone.0025843. Epub 2011 Oct 5.
• The urokinase-type plasminogen activator receptor (uPAR), a glycosylphosphatidylinositol (GPI) anchored membrane protein, regulates urokinase (uPA) protease activity, chemotaxis, cell-cell interactions, and phagocytosis of apoptotic cells. uPAR expression is increased in cytokine or bacteria activat
• PMID 21998707

• Trypanosoma brucei: reduction of GPI-phospholipase C protein during differentiation is dependent on replication of newly transformed cells.

• Subramanya S1, Armah DA, Mensa-Wilmot K.
• Experimental parasitology.Exp Parasitol.2010 Jul;125(3):222-9. doi: 10.1016/j.exppara.2010.01.014. Epub 2010 Jan 28.
• The protozoan parasite Trypanosoma brucei lives in the bloodstream of vertebrates or in a tsetse fly. Expression of a GPI-phospholipase C polypeptide (GPI-PLCp) in the parasite is restricted to the bloodstream form. Events controlling the amount of GPI-PLCp expressed during differentiation are not c
• PMID 20109448

Japanese Journal

• 癌・CEAは分泌型で、正常大腸粘膜上皮・CEAは膜結合型であり、この違いはそれぞれの細胞におけるGPI-PLD発現の有無によるという仮説の提唱

• 日本分子腫瘍マーカー研究会誌 18, 28-29, 2002
• NAID 130004436288

• ラット歯髄アルカリ性ホスファターゼの電気泳動的解析

• 歯科基礎医学会雑誌 43(1), 17-33, 2001-02-20
• NAID 110003166763

• ラット歯髄アルカリ性ホスファターゼの電気泳動的解析

• 歯科基礎医学会雑誌 43(1), 17-33, 2001
• NAID 130003815455

Related Links

• Cysteine-less glycosylphosphatidylinositol-specific ...

Glycosylphosphatidylinositol (GPI)-specific phospholipases are highly valuable for studying the structure and function of GPIs. GPI-specific phospholipase C (GPI-PLC) from Trypanosoma brucei and phosphatidylinositol-specific ...

• Glycosylphosphatidylinositol-anchored proteins: structure ...

1. Biochem Cell Biol. 2002;80(5):535-49. Glycosylphosphatidylinositol-anchored proteins: structure, function, and cleavage by phosphatidylinositol-specific phospholipase C. Sharom FJ(1), Lehto MT. Author ...

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★リンクテーブル★

リンク元	「GPI-PLC」「グリコシルホスファチジルイノシトール特異的ホスホリパーゼC」「glycosylphosphatidylinositol diacylglycerol-lyase」
関連記事	「specific」「C」「glycosylphosphatidylinositol」「Cs」「Cd」

「GPI-PLC」

　　[★]

• グリコシルホスファチジルイノシトール特異的ホスホリパーゼC

関

glycosylphosphatidylinositol diacylglycerol-lyase、glycosylphosphatidylinositol-specific phospholipase C

「グリコシルホスファチジルイノシトール特異的ホスホリパーゼC」

　　[★]

英

glycosylphosphatidylinositol-specific phospholipase C、GPI-PLC

関

グリコシルホスファチジルイノシトールジアシルグリセロールリアーゼ

「glycosylphosphatidylinositol diacylglycerol-lyase」

　　[★]

グリコシルホスファチジルイノシトールジアシルグリセロールリアーゼ

関

glycosylphosphatidylinositol-specific phospholipase C、GPI-PLC

「specific」

　　[★]

• adj.

• (～に関して)明確な、はっきりとした(exact precise)、具体的な(in, about)
• (比較)(限定)特定の(particular)、一定の(⇔general)
• (～に)特有の、独特の(to)
• (比較)(医学)(～に)渡航のある(for)。特殊な
• (生物)(生物)種の
• 医学)特異の
• (物理)比の。物質固有の。単位質量・長さ・面積・容積で

n.

関

specifically、specificity

　 　 　 　 　 　

「C」

　　[★]

• 炭素 carbon
• シトシン cytosine
• システイン cysteine
• シチジン
• セルシウス度 摂氏 degrees Celsius degree C
• 産婦人科領域で「子宮外頚 子宮外頚部 exocervix」を表現するための略語

　 　 　 　

「glycosylphosphatidylinositol」

　　[★]

グリコシルホスファチジルイノシトール

関

glycosyl-phosphatidylinositol、glycosylphosphatidylinositol anchor、GPI

「Cs」

　　[★] セシウム, caesium, cesium 　

「Cd」

　　[★] カドミウム

関

cadmium