glia maturation factor

グリア成熟因子

WordNet

1. be a contributing factor; "make things factor into a companys profitability"
2. any of the numbers (or symbols) that form a product when multiplied together
3. an independent variable in statistics
4. anything that contributes causally to a result; "a number of factors determined the outcome"
5. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
6. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
7. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
8. a concept whose truth can be proved; "scientific hypotheses are not facts"
9. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
10. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
11. coming to full development; becoming mature (同)ripening, maturement

PrepTutorEJDIC

1. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
2. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
3. 成熟,円熟

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/01/31 20:39:22」(JST)

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[Wiki en表示]

glia maturation factor, beta
Identifiers
Symbol	GMFB
Entrez	2764
HUGO	4373
OMIM	601713
RefSeq	NM_004124
UniProt	P60983
Other data
Locus	Chr. 14 q22.1

glia maturation factor, gamma
Identifiers
Symbol	GMFG
Entrez	9535
HUGO	4374
OMIM	604104
RefSeq	NM_004877
UniProt	O60234
Other data
Locus	Chr. 19 q13.2

Glia maturation factor is a nerve growth factor implicated in nervous system development, angiogenesis and immune function.

The structures of mouse glia maturation factors beta and gamma, solved by both crystallography and NMR, reveal similarities and critical differences with ADF-H (actin depolymerization factor homology) domains and suggest new means of experimentally addressing the function of this protein family.

References

See also

Stereo ribbon diagram of the crystal structure of GMFG. Spectral coloring is from blue (N-terminus) to red (C-terminus). Secondary structural elements are indicated

• Glia maturation factor at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

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• 1. 血友病患者における第VIIIおよび第IX因子阻害物質 factor viii and factor ix inhibitors in patients with hemophilia
• 2. 骨髄造血の制御 regulation of myelopoiesis
• 3. 直接トロンビン阻害剤および直接Xa因子阻害剤による抗凝固療法 anticoagulation with direct thrombin inhibitors and direct factor xa inhibitors
• 4. 血管新生阻害剤の概要 overview of angiogenesis inhibitors
• 5. 後天性の凝固因子阻害物質 acquired inhibitors of coagulation

English Journal

• A new method for generating high purity motoneurons from mouse embryonic stem cells.

• McCreedy DA1, Brown CR, Butts JC, Xu H, Huettner JE, Sakiyama-Elbert SE.
• Biotechnology and bioengineering.Biotechnol Bioeng.2014 Oct;111(10):2041-55. doi: 10.1002/bit.25260. Epub 2014 Jun 4.
• A common problem with using embryonic stem (ES) cells as a source for analysis of gene expression, drug toxicity, or functional characterization studies is the heterogeneity that results from many differentiation protocols. The ability to generate large numbers of high purity differentiated cells fr
• PMID 24842774

• Suppression of glia maturation factor expression prevents 1-methyl-4-phenylpyridinium (MPP(+))-induced loss of mesencephalic dopaminergic neurons.

• Khan MM1, Zaheer S1, Nehman J1, Zaheer A2.
• Neuroscience.Neuroscience.2014 Sep 26;277:196-205. doi: 10.1016/j.neuroscience.2014.07.003. Epub 2014 Jul 10.
• Inflammation mediated by glial activation appears to play a critical role in the pathogenesis of Parkinson disease (PD). Glia maturation factor (GMF), a proinflammatory protein predominantly localized in the central nervous system was isolated, sequenced and cloned in our laboratory. We have previou
• PMID 25016212

• The complex morphology of reactive astrocytes controlled by fibroblast growth factor signaling.

• Kang K1, Lee SW, Han JE, Choi JW, Song MR.
• Glia.Glia.2014 Aug;62(8):1328-44. doi: 10.1002/glia.22684. Epub 2014 May 3.
• Astrocytes are the most abundant cell-type of the human brain and play a variety of roles in brain homeostasis and synaptic maturation, under normal conditions. However, astrocytes undergo dramatic pathological changes in response to brain injury, such as reactive gliosis and glial scar formation. A
• PMID 24796693

Japanese Journal

• Diminished degradation of myelin basic protein by anti-sulfatide antibody and interferon-γ in myelin from glia maturation factor-deficient mice

• Neuroscience research : the official journal of the Japan Neuroscience Society 58(2), 156-163, 2007-06-01
• NAID 10024415078

• Lithium : Potential Therapeutics Against Acute Brain Injuries and Chronic Neurodegenerative Diseases

• Journal of pharmacological sciences 99(4), 307-321, 2005-12-20
• NAID 10025731486

• 遺伝子発現の網羅的解析を応用した疾患関連遺伝子探索

• 神戸女子大学家政学部紀要 37, 25-28, 2004-03
• NAID 40006235091

Related Links

• Glia maturation factor. - ResearchGate

Overexpression of glia maturation factor reinstates susceptibility to myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in glia maturation factor deficient mice Smita Zaheer, Yanghong Wu, , ...

• Glia Maturation Factor -Neoscientific|peptide service|gmp ...

Neoscientific| Study proteins in their cellular context - detect, measure and explore protein expression, identity and function using Neoscientific Protein Biology Products. ... +1888.754.5670 +1857.259.4898 (Int’l) +44 020.8123.1558 ...

Related Pictures

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★リンクテーブル★

リンク元	「グリア成熟因子」
関連記事	「fact」「factor」「maturation」

「グリア成熟因子」

　　[★]

英

glia maturation factor

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「maturation」

　　[★]

• n.

• 成熟

関

maturational、mature、maturing、ripening