WordNet

direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
(often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
the 14th letter of the Roman alphabet (同)n
of or belonging to the epithelium; "epithelial layer"
official routes of communication; "you have to go through channels"

PrepTutorEJDIC

〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
nitrogenの化学記号

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1. 腎集合管ナトリウムチャンネルの遺伝的障害：リドル症候群および偽性低アルドステロン症1型genetic disorders of the collecting tubule sodium channel liddles syndrome and pseudohypoaldosteronism type 1 [show details]
…abnormalities in the function of the collecting tubule sodium channel, also called the epithelial sodium channel (ENaC) or the amiloride-sensitive sodium channel: ENaC function is increased in Liddle syndrome …
2. 低アルドステロン症（4型RTA）の病因、診断、および治療 etiology diagnosis and treatment of hypoaldosteronism type 4 rta [show details]
…PHA 1: Autosomal recessive PHA 1 (MIM #264350), affects the collecting tubule sodium channel (also called the epithelial sodium channel, or ENaC). The defect is permanent and affects all aldosterone target …
3. 成人における高カリウム血症の原因および評価causes and evaluation of hyperkalemia in adults [show details]
…increasing the size of the potassium secretory pool . Increased activity of apical epithelial sodium channels (ENaC), through both aldosterone-independent and aldosterone-dependent mechanisms . This induction …
4. 腎でのマグネシウム処理における利尿剤の有効性effect of diuretics on magnesium handling by the kidney [show details]
…diuretics (amiloride, triamterene, and spironolactone) decrease sodium entry mediated by epithelial sodium channels in the connecting tubule and cortical collecting tubule , an effect that enhances magnesium …
5. 利尿剤とカルシウムバランスdiuretics and calcium balance [show details]
…triamterene block sodium entry into the tubular cell by closing luminal sodium channels (called epithelial sodium channels). Spironolactone and eplerenone block the mineralocorticoid receptor. Amiloride increases…

English Journal

A spatial model of fluid recycling in the airways of the lung.

Sharp K1, Crampin E2, Sneyd J3.
Journal of theoretical biology.J Theor Biol.2015 Oct 7;382:198-215. doi: 10.1016/j.jtbi.2015.06.050. Epub 2015 Jul 10.
The genetic disease cystic fibrosis (CF) is a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and results in viscous mucus and impaired mucociliary clearance leading to chronic recurring pulmonary infections. Although extensive experimental research has been conducte
PMID 26169010

Airway hydration and COPD.

Ghosh A1, Boucher RC1, Tarran R2.
Cellular and molecular life sciences : CMLS.Cell Mol Life Sci.2015 Oct;72(19):3637-52. doi: 10.1007/s00018-015-1946-7. Epub 2015 Jun 12.
Chronic obstructive pulmonary disease (COPD) is one of the prevalent causes of worldwide mortality and encompasses two major clinical phenotypes, i.e., chronic bronchitis (CB) and emphysema. The most common cause of COPD is chronic tobacco inhalation. Research focused on the chronic bronchitic pheno
PMID 26068443

Estrogen, progesterone, and genistein differentially regulate levels of expression of α-, β-, and γ-epithelial sodium channel (ENaC) and α-sodium potassium pump (Na(+)/K(+)-ATPase) in the uteri of sex steroid-deficient rats.

Chinigarzadeh A1, Muniandy S2, Salleh N3.
Theriogenology.Theriogenology.2015 Oct 1;84(6):911-26. doi: 10.1016/j.theriogenology.2015.05.029. Epub 2015 Jun 6.
Estrogen, progesterone, and genistein could induce changes in uterine fluid volume and Na(+) concentration. Progesterone upregulates expression of epithelial sodium channel (ENaC) and Na(+)/K(+)-ATPase which contributed toward these changes. However, effects of estrogen and genistein were unknown. T
PMID 26154487