WordNet

any creature of exceptional size
someone or something that is abnormally large and powerful (同)goliath, behemoth, monster, colossus
a very large person; impressive in size or qualities (同)hulk, heavyweight, whale
an imaginary figure of superhuman size and strength; appears in folklore and fairy tales
an unusually large enterprise; "Walton built a retail giant"
acquire pigment; become colored or imbued
any substance whose presence in plant or animal tissues produces a characteristic color
color or dye with a pigment; "pigment a photograph"
dry coloring material (especially a powder to be mixed with a liquid to produce paint, etc.)
present at birth but not necessarily hereditary; acquired during fetal development (同)inborn, innate

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Hydrosurgery, a new therapeutic perspective in early care of giant congenital nevi: a preliminary series of four cases.

Coyette M1, Elajmi A1, Bayet B1, Lengelé B2.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS.J Plast Reconstr Aesthet Surg.2014 Aug;67(8):1063-9. doi: 10.1016/j.bjps.2014.04.019. Epub 2014 May 2.
BACKGROUND: Congenital melanocytic nevi are present at birth or may appear in the first weeks of life. Small and medium-size lesions are relatively common, affecting approximately 1% of newborns; large or giant melanocytic nevi occur in 1/20,000-1/500,000 births. The main concern raised by these les
PMID 24880574

Insight into evolution of a giant congenital nevomelanocytic nevus over 14 years.

Sathyanarayana BD1, Basavaraj HB, Nischal KC, Swaroop MR, Lavanya MS, Okram S.
Indian journal of dermatology, venereology and leprology.Indian J Dermatol Venereol Leprol.2014 May-Jun;80(3):243-6. doi: 10.4103/0378-6323.132252.
Giant congenital nevomelanocytic nevus (GCNN) is a rare variant of congenital melanocytic nevus measuring >20 cm in size that often has a garment-like distribution. Regular follow up is recommended because of a risk of melanoma transformation of 4.6%. We report a 14-year-old boy with gradual regr
PMID 24823402

Skin of patients with large/giant congenital melanocytic nevi shows increased mast cells.

Salgado CM1, Silver RB, Bauer BS, Basu D, Schmitt L, Khakoo Y, Reyes-Múgica M.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.Pediatr Dev Pathol.2014 May-Jun;17(3):198-203. doi: 10.2350/14-02-1444-OA.1. Epub 2014 Mar 28.
Nevocytes (NC) and mastocytes (MC) have different progenitors but share stem cell factor as regulator/activator of NC and for differentiation/proliferation of MC. Both cell types express stem cell factor receptor CD117. We hypothesize that large/giant congenital melanocytic nevi (L/GCMN) may associa
PMID 24679055

松田就人
慶應醫學 80(4), 141-150, 2003-12-25
… 原著Both nevus cells and melanocytes are derived from the neural crest. … The etiology of giant congenital nevus cell nevus(GCNN) is thought to be the cloned proliferation of melanoblasts, the precursors of melanocytes, during development and distribution in a restricted area. … Nevus cells, however, are unable to migrate into the epidermis, and many of them remain in the dermis. …
NAID 120001129311

河野太郎,野崎幹弘,菊池雄二,大久保麗,岩坂督,堀圭二朗
THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE 23(1), 11-14, 2002
… A 1-year-old Asian girl with a congenital melanocytic nevus on her back was seen at the outpatient clinic. … Clinical examination revealed a dark brown melanocytic nevus that measured 13×11cm. … Histological findings showed superficial compound nevus and there is no evidence of malignancy. …
NAID 130004630698

山本明史,山崎直也,田口理史,石原和之
Ｓｋｉｎ　Ｃａｎｃｅｒ 11(2), 184-188, 1996
… Precursor lesions of congenital giant pigmented nevus existed in 4 out of 15 cases (26.4%), but not definitely in other 11 cases. …
NAID 130001078031